M R N Roxann Neumann

Predicting the survival of bladder carcinoma patients treated with radical cystectomy

Clinical outcomes vary for patients treated with radical cystectomy. The authors sought to identify factors associated with the survival of patients treated with radical cystectomy for urothelial carcinoma of the urinary bladder.

Survival of patients with carcinoma in situ of the urinary bladder

To the authors knowledge, the long term follow‐up of patients with carcinoma in situ of the urinary bladder is limited.

Substaging of T1 bladder carcinoma based on the depth of invasion as measured by micrometer: A new proposal.

A significant number of T1 bladder carcinoma patients are understaged by transurethral resection of the bladder (TURB), indicating a substantial need for more accurate staging.

Papillary urothelial neoplasms of low malignant potential. Clinical and biologic implications.

Knowledge of the long term outcomes of patients with papillary urothelial neoplasms of low malignant potential (LMP) is limited.

Cancer heterogeneity and its biologic implications in the grading of urothelial carcinoma

Urothelial carcinoma of the bladder often contains areas with different histologic grades. The influence of cancer heterogeneity on grading and its relation to patient outcome is uncertain.

Flat intraepithelial lesions of the urinary bladder

In the 1998 World Health Organization and International Society of Urologic Pathology (WHO/ISUP) classification system for bladder neoplasms, flat intraepithelial lesions of the urinary bladder were categorized as reactive atypia, atypia of unknown significance, dysplasia, and carcinoma in situ. The clinical outcomes of patients diagnosed with these atypical urothelial proliferations are uncertain.

Tumor Size Predicts the Survival of Patients with Pathologic Stage T2 Bladder Carcinoma A Critical Evaluation of the Depth of Muscle Invasion

Accurate examination of radical cystectomy specimens is critical for stratifying patients into prognostically important groups and determining the need for adjuvant treatment. Evidence has accumulated that cancers invading the superficial muscle wall (T2a) behave similarly to those invading the deep muscle wall (T2b). Quantitative analysis of the depth of invasion in relation to patient outcome is needed.

Predictors of survival for prostate carcinoma patients treated with salvage radical prostatectomy after radiation therapy

Salvage radical prostatectomy is a treatment option for patients with recurrent cancer following radiation therapy. This study was conducted to identify predictors of survival for patients treated with salvage radical prostatectomy.

Urothelial papilloma of the bladder: Clinical and biologic implications

An international consensus has been reached regarding diagnostic criteria for papilloma of the urinary bladder. However, the incidences of recurrence and progression in patients with urothelial papilloma are uncertain.

p53 Protein overexpression is associated with increased cell proliferation in patients with locally recurrent prostate carcinoma after radiation therapy

The biologic changes in recurrent prostate carcinoma following radiation therapy are not fully understood. The authors sought to determine the level of p53 protein overexpression and its association with cellular proliferation (Ki‐67 labeling index), glutathione S‐transferase‐π (GST‐π) expression, and other clinical pathologic findings in patients with locally persistent prostate carcinoma after radiation therapy.