Is this you? Create Your Porfile
Avatar

Manoj Patel

Bristol-Myers Squibb

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Manoj Patel is active.

Explore More

Publication

Featured researches published by Manoj Patel.

Bioorganic & Medicinal Chemistry Letters | 2015

Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors

B. Narasimhulu Naidu; Margaret E. Sorenson; Manoj Patel; Yasutsugu Ueda; Jacques Banville; Francis Beaulieu; Sagarika Bollini; Ira B. Dicker; Helen Higley; Zeyu Lin; Lori Pajor; Dawn D. Parker; Brian Terry; Ming Zheng; Alain Martel; Nicholas A. Meanwell; Mark Krystal; Michael A. Walker

Integration of viral DNA into the host cell genome is an obligatory process for successful replication of HIV-1. Integrase catalyzes the insertion of viral DNA into the target DNA and is a validated target for drug discovery. Herein, we report the synthesis, antiviral activity and pharmacokinetic profiles of several C2-carbon-linked heterocyclic pyrimidinone-4-carboxamides that inhibit the strand transfer step of the integration process.

Archive | 2009

Bridged heterocycles as hiv integrase inhibitors

Francis Beaulieu; Carl Ouellet; B. Narasimhulu Naidu; Manoj Patel; Yasutsugu Ueda; Timothy P. Connolly; Jonathan R. Weiss; Michael A. Walker; Nicholas A. Meanwell; Kevin Peese; Margaret E. Sorenson

Archive | 2015

PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

B. Narasimhulu Naidu; Manoj Patel; Jeffrey L. Romine; R Laurent Denis; Tao Wang; Zhongxing Zhang; John F. Kadow

Archive | 2015

PYRAZOLOPYRIMIDINE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

B. Narasimhulu Naidu; Michael A. Walker; Margaret E. Sorenson; Manoj Patel; Zhizhen Barbara Zheng; John F. Kadow; Bin Zheng; Martin D. Eastgate; Ke Chen; Francisco González-Bobes

Archive | 2017

Inhibidores de la replicación del virus de la inmunodeficiencia humana

B. Narasimhulu Naidu; Manoj Patel; Stanley D'andrea; Zhizhen Barbara Zheng; Timothy P. Connolly; David R. Langley; Kevin Peese; Zhongyu Wang; Michael A. Walker; John F. Kadow

Archive | 2016

DERIVADOS DEL ÁCIDO PIRIDIN-3-ILACÉTICO COMO INHIBIDORES DE LA REPLICACIÓN DEL VIRUS DE INMUNODEFICIENCIA HUMANA

John F. Kadow; Zhongxing Zhang; Tao Wang; Denis R. St. Laurent; Jeffrey L. Romine; Manoj Patel; B. Narasimhulu Naidu

Archive | 2016

MACROCICLOS DE PIRAZOLOPIRIMIDINA COMO INHIBIDORES DE LA REPLICACIÓN DEL VIRUS DE LA INMUNODEFICIENCIA HUMANA

Francisco González-Bobes; Ke Chen; Martin D. Eastgate; Bin Zheng; John F. Kadow; Zhizhen Barbara Zheng; Manoj Patel; Margaret E. Sorenson; Michael A. Walker; B. Narasimhulu Naidu

Archive | 2016

Dérivés de l'acide pyridin-3-yl-acétique utilisés comme inhibiteurs de la réplication du virus de l'immunodéficience humaine

John F. Kadow; B. Narasimhulu Naidu; Manoj Patel; Jeffrey L. Romine; R Laurent Denis; Tao Wang; Zhongxing Zhang

Archive | 2014

Inhibiteurs de la réplication du virus de l'immunodéficience humaine

B. Narasimhulu Naidu; Manoj Patel; Kevin Peese; Zhongyu Wang

Archive | 2014

Replication inhibitors of human immunodeficiency virus

B. Narasimhulu Naidu; Manoj Patel; Kevin Peese; Zhongyu Wang

Explore More

Collaboration

Dive into the Manoj Patel's collaboration.

Top Co-Authors
Avatar

B. Narasimhulu Naidu

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Kevin Peese

Memorial Sloan Kettering Cancer Center

View shared research outputs
Top Co-Authors
Avatar

Michael A. Walker

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

John F. Kadow

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Zhongyu Wang

ViiV Healthcare

View shared research outputs
Top Co-Authors
Avatar

Margaret E. Sorenson

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Timothy P. Connolly

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Zhizhen Barbara Zheng

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

David R. Langley

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Nicholas A. Meanwell

Bristol-Myers Squibb

View shared research outputs
Explore More
Researchain Logo
Decentralizing Knowledge