Marco Tulio Souza

TCT-366 Predictors of major complications secondary to cardiac catheterization through femoral access in ST elevation in acute myocardial infarction during Pharmaco-Invasive Therapy.

ST elevation acute myocardial infarction (STEMI) and recent use of thrombolytics are risk factors for complications related to catheterism, especially in the femoral access. Our goal is to analyze predictors of major complications due to this invasive procedure in patients with STEMI undergoing

Discordant congenital Zika virus infection in dizygotic twins: a case report

Background: Discordant clinical outcomes in congenital infectious disorders have been described, such as in Cytomegalovirus, toxoplasmosis and HIV infection, most of then in dizygotic twin pregnancies. In Brazil, since 2015, more than 2800 cases of congenital Zika infection (CZI) were confirmed. To date, three cases of discordant CZI infection in twins were reported, one case in monozygotic pregnancy and two cases in dizygotic twin pregnancies. Methods & Materials: Here, we describe a case report with the clinical presentation of discordant twin siblings, one with microcephaly

TCT-525 Initial experience with the use of fractional flow reserve in percutaneous intervention of transplant renal artery stenosis

RESULTS In Cohort 1, CFR was significantly lower (2.12 0.79 vs. 2.56 0.63; p<0.001) and HMR was significantly higher (2.61 1.22 vs. 2.31 0.89; p1⁄40.04) in vessels with CAD than the vessels without CAD, within the same patient. mMR was equivalent in obstructed and nonobstructed vessels: 1.54 0.77 vs. 1.53 0.57; p1⁄40.90. Cohort 2 confirmed these findings, showing a significant relationship for CFR and HMR with diameter stenosis % (b1⁄4-0.013, 95%CI [-0.016 to -0.010]; p<0.001 for CFR and b1⁄40.008, 95%CI [0.004 to 0.011]; p<0.001 for HMR per 1%), while mMR was independent of diameter stenosis % (b1⁄40.002, 95%CI [-0.001 to 0.004] per 1%; p1⁄40.15). No association was found between mMR and any of the risk factors for cardiovascular disease.

TCT-495 A prospective 9-month comparison of the coronary vasomotor response associated with a biodegradable polymer sirolimus-eluting stent and a bare metal stent.

BACKGROUND The BioFreedom (BFD) drug-coated stent (Biosensors, Singapore) is a new polymer/carrier-free technology that incorporates a 316L stainless steel platform, which has been modified with a proprietary surface treatment resulting in a selectively micro-structured abluminal surface which allows adhesion of the antiproliferative agent (Biolimus) to the abluminal surface of the stent without a polymer or binder on a drug dose of 15.6mg per mm of stent length. Our objective was to investigate the efficacy of the BFD stent in inhibiting neointimal hyperplasia (NIH) in patients treated in daily practice with serial angiographic follow-up evaluations.