Maria J Maynard

Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohort

Objective: To examine the association between childhood diet and cardiovascular mortality. Design: Historical cohort study. Setting: 16 centres in England and Scotland. Participants: 4028 people (from 1234 families) who took part in Boyd Orr’s survey of family diet and health in Britain between 1937 and 1939 followed up through the National Health Service central register. Exposures studied: Childhood intake of fruit, vegetables, fish, oily fish, total fat, saturated fat, carotene, vitamin C, and vitamin E estimated from household dietary intake. Main outcome measures: Deaths from all causes and deaths attributed to coronary heart disease and stroke. Results: Higher childhood intake of vegetables was associated with lower risk of stroke. After controlling for age, sex, energy intake, and a range of socioeconomic and other confounders the rate ratio between the highest and lowest quartiles of intake was 0.40 (95% confidence interval 0.19 to 0.83, p for trend 0.01). Higher intake of fish was associated with higher risk of stroke. The fully adjusted rate ratio between the highest and lowest quartile of fish intake was 2.01 (95% confidence interval 1.09 to 3.69, p for trend 0.01). Intake of any of the foods and constituents considered was not associated with coronary mortality. Conclusions: Aspects of childhood diet, but not antioxidant intake, may affect adult cardiovascular risk.

Ethnic differences in overweight and obesity in early adolescence in the MRC DASH study: the role of adolescent and parental lifestyle

BACKGROUND Ethnicity is a consistent correlate of excess weight in youth. We examine the influence of lifestyles on ethnic differences in excess weight in early adolescence in the UK. METHOD Data were collected from 6599 pupils, aged 11-13 years in 51 schools, on dietary practices and physical activity, parental smoking and overweight, and on overweight and obesity (using International Obesity Task Force criteria). RESULTS Skipping breakfast [girls odds ratio (OR) 1.74, 95% confidence interval (CI) 1.30-2.34; boys OR 2.06; CI 1.57-2.70], maternal smoking (girls OR 2.04, CI 1.49-2.79; boys OR 1.63, CI 1.21-2.21) and maternal overweight (girls OR 2.01, CI 1.29-3.13; boys OR 2.47, CI 1.63-3.73) were associated with obesity. Skipping breakfast, more common among girls, was associated with other poor dietary practices. Compared with White UK peers, Black Caribbeans (girls OR 1.62, CI 1.24-2.12; boys OR 1.49, CI 1.15-1.95) and Black Africans (girls OR 1.96, CI 1.52-2.53; boys OR 2.50, CI 1.92-3.27) were more likely to skip breakfast and engage in other poor dietary practices, and Indians were least likely. White Other boys reported more maternal smoking (OR 1.37, CI 1.03-1.82). All these reports were more common among those born in the UK than those born elsewhere. Black Caribbean girls were more likely to be overweight (OR 1.38, CI 1.02-1.87) and obese (OR 1.65, CI 1.05-2.58), Black African girls to be overweight (OR 1.35, CI 1.02-1.79) and White Other boys to be overweight (OR 1.37, CI 1.00-1.88) and obese (OR 1.86, CI 1.15-3.00). Adverse dietary habits and being born in the UK contributed to these patterns. CONCLUSION These findings signal a potential exacerbating effect on ethnic differences in obesity if adverse dietary habits persist. Combined adolescent and parent-focused interventions should be considered.

Overweight, obesity and high blood pressure in an ethnically diverse sample of adolescents in Britain: the Medical Research Council DASH study

Objectives:To examine the impact of overweight on mean, high normal and high blood pressure in early adolescence, and how this relates to ethnicity and socio-economic status.Design:Cross-sectional study with anthropometric and blood pressure measurements.Setting:A total of 51 secondary schools in London.Sample:A total of 6407 subjects, 11–13 years of age, including 1204 White UK, 698 Other Whites, 911 Black Caribbeans, 1065 black Africans, 477 Indians and 611 Pakistanis/Bangladeshis.Main outcome measures:Mean, high normal (gender, age and height-percentile-specific 90–94th percentile) and high (⩾95th percentile) blood pressure.Results:Based on the International Obesity Task Force age-specific thresholds, 19% of boys and 23% of girls were overweight, and 8% of each were obese. Overweight and obesity were associated with large increases in the prevalence of high normal and high blood pressures compared with those not overweight. The increases in the prevalence of high systolic pressure associated with overweight were as follows: boys, odds ratio 2.50 (95% confidence intervals 1.73–3.60) and girls 3.39 (2.36–4.85). Corresponding figures for obesity were: boys 4.31 (2.82–6.61) and girls 5.68 (3.61–8.95). Compared with their White British peers, obesity was associated with larger effects on blood pressure measures only among Indians, despite more overweight and obesity among black Caribbean girls and overweight among Black African girls. The effect of socio-economic status was inconsistent.Conclusions:The tendency to high blood pressure among adult Black African origin populations was not evident at these ages. These results suggest that the rise in obesity in adolescence portends a rise in early onset of cardiovascular disease across ethnic groups, with Indians appearing to be more vulnerable.

Anthropometry and blood pressure differences in black caribbean, African, South Asian and white adolescents : the MRC DASH study

Objectives In this first large-scale study of ethnic differences in blood pressure (BP) among British adolescents, we examine the differences in BP levels in adolescence and the extent to which age, sex, body size and stage of maturation affect any observed differences. Method A total of 6365 11–13 year olds (including 1189 white, 907 black Caribbeans and 1056 black Africans, 473 Indians, 605 Pakistanis and Bangladeshis, and 548 of mixed ethnicity) had systolic blood pressure (SBP) and diastolic blood pressure (DBP), anthropometry and pubertal stage measured in 2003. Results Compared with their white UK counterparts, black Caribbean and African boys were taller, and black Caribbean and African girls were taller, larger and matured earlier. Except for DBP among Indian girls, BP in minority groups was generally lower than in white UK children. Adjusted for age, height and body mass index, mean SBP was 109.1 mmHg (95% confidence interval 108.4, 109.8) and DBP 65.7 mmHg (65.2, 66.3) among white UK boys. Black Caribbean boys had lower SBP (−2.0; −3.2, −0.9 mmHg) and DBP (−1.5; −2.3, −0.6), and black African (−2.3; −3.4, −1.2) and mixed ethnicity (−1.6; −2.9, −0.3) boys had lower SBP. Adjusted SBP was 108.5 (107.8, 109.3) and DBP was 67.5 mmHg (66.9, 68.1) among white UK girls. Pakistani (−1.8; −3.2, −0.4) and black African (−1.1; −1.9, −0.3) girls had lower SBP and Indian girls (1.2; 0.1, 2.4) had higher DBP. Unlike African American girls, late puberty was not associated with higher BP in minority groups. Conclusion At these ages, the ethnic-specific patterns in BP in adulthood were not observed. Apart from higher DBP for Indian girls, BP in minority groups was generally lower than their white UK counterparts. Targeting intervention in adolescence may be a critical opportunity for preventing ethnic differences in BP in later life.

Emergence of ethnic differences in blood pressure in adolescence: The Determinants of Adolescent Social Well-Being and Health Study

The cause of ethnic differences in cardiovascular disease remains a scientific challenge. Blood pressure tracks from late childhood to adulthood. We examined ethnic differences in changes in blood pressure between early and late adolescence in the United Kingdom. Longitudinal measures of blood pressure, height, weight, leg length, smoking, and socioeconomic circumstances were obtained from London, United Kingdom, schoolchildren of White British (n=692), Black Caribbean (n=670), Black African (n=772), Indian (n=384), and Pakistani and Bangladeshi (n=402) ethnicity at 11 to 13 years and 14 to 16 years. Predicted age- and ethnic-specific means of blood pressure, adjusted for anthropometry and social exposures, were derived using mixed models. Among boys, systolic blood pressure did not differ by ethnicity at 12 years, but the greater increase among Black Africans than Whites led to higher systolic blood pressure at 16 years (+2.9 mm Hg). Among girls, ethnic differences in mean systolic blood pressure were not significant at any age, but while systolic blood pressure hardly changed with age among White girls, it increased among Black Caribbeans and Black Africans. Ethnic differences in diastolic blood pressure were more marked than those for systolic blood pressure. Body mass index, height, and leg length were independent predictors of blood pressure, with few ethnic-specific effects. Socioeconomic disadvantage had a disproportionate effect on blood pressure for girls in minority groups. The findings suggest that ethnic divergences in blood pressure begin in adolescence and are particularly striking for boys. They signal the need for early prevention of adverse cardiovascular disease risks in later life.

Developing obesity prevention interventions among minority ethnic children in schools and places of worship: The DEAL (DiEt and Active Living) study

BackgroundChildhood obesity is a major public health concern with serious implications for the sustainability of healthcare systems. Studies in the US and UK have shown that ethnicity is consistently associated with childhood obesity, with Black African origin girls in particular being more vulnerable to overweight and obesity than their White peers. Little is known, however, about what promotes or hinders engagement with prevention programmes among ethnic minority children.Methods/DesignThis paper describes the background and design of an exploratory study conducted in London, UK. The aim of the study was to assess the feasibility, efficacy and cultural acceptability of child- and family-based interventions to reduce risk factors for childhood and adolescent obesity among ethnic minorities. It investigated the use of a population approach (in schools) and a targeted approach (in places of worship). We used a mixture of focus group discussions, in-depth interviews and structured questionnaires to explore what children, parents, grandparents, teachers and religious leaders think hinder and promote engagement with healthy eating and active living choices. We assessed the cultural appropriateness of validated measures of physical activity, dietary behaviour and self efficacy, and of potential elements of interventions informed by the data collected. We are also currently assessing the potential for wider community support (local councils, community networks, faith forums etc) of the intervention.DiscussionAnalysis of the data is ongoing but the emergent findings suggest that while the school setting may be better for the main implementation of healthy lifestyle interventions, places of worship provide valuable opportunities for family and culturally specific support for implementation. Tackling the rise in childhood and adolescent obesity is a policy priority, as reflected in a range of government initiatives. The study will enhance such policy by developing the evidence base about culturally acceptable interventions to reduce the risk of obesity in children.

How accurate is self reported birth weight among the elderly

The effect of early life influences on adult health is a central topic in current epidemiological research. For instance, growth and development in utero and in infancy have been linked to cardiovascular disease.1 In empirical research in this field, birth weight is often used as an indicator of health and nutrition in utero. There are two main sources of birthweight data: birth records and the memories of subjects or their families, or both. Where the subjects are elderly, however, early birth records with recorded birth weights are not easy to find and the recovery rate is generally low.2Where there are no surviving birth records with birthweight data and where the subjects parents cannot be asked, the subjects own testimony is the only possible source of such data. But can self reported birth weight be relied upon in the absence of data from clinical or administrative sources? Birth weights recalled by mothers have been found to correlate highly with those found in official records.3 The accuracy of self reported birth weights, however, is less certain—some studies have reported a poor degree of correspondence between birth weights recorded in official records and self reported birth weights.4 Other researchers have found that birth weights from these two sources correlate reasonably well.5 Most investigations of the validity of self reported birth weight have typically used subjects who were middle aged or younger. In the investigation reported here, we use data collected in a study of childhood diet and health and disease in later life to estimate the accuracy of the self reported birth weights for an older age group of 57 to 77 year old women and men. It is important to note that the results reported are only …

Racism, ethnic density and psychological well-being through adolescence : evidence from the Determinants of Adolescent Social Well-Being and Health longitudinal study

Objective. To investigate the effect of racism, own-group ethnic density, diversity and deprivation on adolescent trajectories in psychological well-being. Design. Multilevel models were used in longitudinal analysis of psychological well-being (total difficulties score (TDS) from Goodmans Strengths and Difficulties Questionnaire, higher scores correspond to greater difficulties) for 4782 adolescents aged 11–16 years in 51 London (UK) schools. Individual level variables included ethnicity, racism, gender, age, migrant generation, socio-economic circumstances, family type and indicators of family interactions (shared activities, perceived parenting). Contextual variables were per cent eligible for free school-meals, neighbourhood deprivation, per cent own-group ethnic density, and ethnic diversity. Results. Ethnic minorities were more likely to report racism than Whites. Ethnic minority boys (except Indian boys) and Indian girls reported better psychological well-being throughout adolescence compared to their White peers. Notably, lowest mean TDS scores were observed for Nigerian/Ghanaian boys, among whom the reporting of racism increased with age. Adjusted for individual characteristics, psychological well-being improved with age across all ethnic groups. Racism was associated with poorer psychological well-being trajectories for all ethnic groups (p<0.001), reducing with age. For example, mean difference in TDS (95% confidence interval) between boys who experienced racism and those who did not at age 12 years=1.88 (+1.75 to+2.01); at 16 years=+1.19 (+1.07 to+1.31). Less racism was generally reported in schools and neighbourhoods with high than low own-group density. Own ethnic density and diversity were not consistently associated with TDS for any ethnic group. Living in more deprived neighbourhoods was associated with poorer psychological well-being for Whites and Black Caribbeans (p<0.05). Conclusion. Racism, but not ethnic density and deprivation in schools or neighbourhoods, was an important influence on psychological well-being. However, exposure to racism did not explain the advantage in psychological well-being of ethnic minority groups over Whites.

Perceived parenting and psychological well-being in UK ethnic minority adolescents

Background Warm, caring parenting with appropriate supervision and control is considered to contribute to the best mental health outcomes for young people. The extent to which this view on ‘optimal’ parenting and health applies across ethnicities, warrants further attention. We examined associations between perceived parental care and parental control and psychological well-being among ethnically diverse UK adolescents. Methods In 2003 a sample of 4349 pupils aged 11–13 years completed eight self-reported parenting items. These items were used to derive the parental care and control scores. Higher score represents greater care and control, respectively. Psychological well-being was based on total psychological difficulties score from Goodmans Strengths and Difficulties Questionnaire, increasing score corresponding to increasing difficulties. Results All minority pupils had lower mean care and higher mean control scores compared with Whites. In models stratified by ethnicity, increasing parental care was associated with lower psychological difficulties score (better mental health) and increasing parental control with higher psychological difficulties score within each ethnic group, compared with reference categories. The difference in psychological difficulties between the highest and lowest tertiles of parental care, adjusted for age, sex, family type and socio-economic circumstances, was: White UK =−2.92 (95% confidence interval −3.72, −2.12); Black Caribbean =−2.08 (−2.94, −1.22); Nigerian/Ghanaian =−2.60 (−3.58, −1.62); Other African =−3.12 (−4.24, −2.01); Indian =−2.77 (−4.09, −1.45); Pakistani/ Bangladeshi =−3.15 (−4.27, −2.03). Between ethnic groups (i.e. in models including ethnicity), relatively better mental health of minority groups compared with Whites was apparent even in categories of low care and low autonomy. Adjusting for parenting scores, however, did not fully account for the protective effect of minority ethnicity. Conclusions Perceived quality of parenting is a correlate of psychological difficulties score for all ethnic groups despite differences in reporting. It is therefore likely that programmes supporting parenting will be effective regardless of ethnicity.

Does cultural integration explain a mental health advantage for adolescents

Background A mental health advantage has been observed among adolescents in urban areas. This prospective study tests whether cultural integration measured by cross-cultural friendships explains a mental health advantage for adolescents. Methods A prospective cohort of adolescents was recruited from 51 secondary schools in 10 London boroughs. Cultural identity was assessed by friendship choices within and across ethnic groups. Cultural integration is one of four categories of cultural identity. Using gender-specific linear-mixed models we tested whether cultural integration explained a mental health advantage, and whether gender and age were influential. Demographic and other relevant factors, such as ethnic group, socio-economic status, family structure, parenting styles and perceived racism were also measured and entered into the models. Mental health was measured by the Strengths and Difficulties Questionnaire as a ‘total difficulties score’ and by classification as a ‘probable clinical case’. Results A total of 6643 pupils in first and second years of secondary school (ages 11–13 years) took part in the baseline survey (2003/04) and 4785 took part in the follow-up survey in 2005–06. Overall mental health improved with age, more so in male rather than female students. Cultural integration (friendships with own and other ethnic groups) was associated with the lowest levels of mental health problems especially among male students. This effect was sustained irrespective of age, ethnicity and other potential explanatory variables. There was a mental health advantage among specific ethnic groups: Black Caribbean and Black African male students (Nigerian/Ghanaian origin) and female Indian students. This was not fully explained by cultural integration, although cultural integration was independently associated with better mental health. Conclusions Cultural integration was associated with better mental health, independent of the mental health advantage found among specific ethnic groups: Black Caribbean and some Black African male students and female Indian students.