Maria Nicolà D'Errico
University of Bari
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Publication
Featured researches published by Maria Nicolà D'Errico.
Journal of Environmental Monitoring | 2011
Piero Lovreglio; Maria Nicolà D'Errico; Silvia Fustinoni; Ignazio Drago; Anna Barbieri; Laura Sabatini; Mariella Carrieri; Pietro Apostoli; Leonardo Soleo
The urinary excretion of t,t-muconic acid (t,t-MA), S-phenylmercapturic acid (SPMA) and urinary benzene and the influence of a smoking habit and of exposure to urban traffic on the urinary excretion of these biomarkers were investigated in 137 male adults from the general population. All subjects were not occupationally exposed to benzene and resident in two cities in Puglia (Southern-Italy). Environmental exposure to benzene was measured using passive personal samplers. The biomarkers t,t-MA, SPMA and urinary benzene were determined in urine samples collected from each subject at the end of the environmental sampling. The percentage of cases above the limit of detection was higher for SPMA and urinary benzene in smokers than in non-smokers, and for airborne benzene and urinary benzene in subjects exposed to urban traffic. Airborne benzene was correlated with the time spent in urban traffic during the environmental sampling. Among the biomarkers, urinary benzene was found to be correlated with airborne benzene only in non-smokers, and with the time spent in urban traffic, both in smokers and non-smokers considered together, and in non-smokers only. Finally, multiple regression analysis showed that the urinary excretion of all the biomarkers was dependent on the number of cigarettes smoked per day and, for urinary benzene, also on the time spent in urban traffic. In conclusion, urinary benzene seems to be a more valid biomarker than t,t-MA and SPMA to assess environmental exposure to extremely low concentrations of benzene. Cigarette smoking prevailed over traffic exhaust fumes in determining the internal dose of benzene.
International Journal of Immunopathology and Pharmacology | 2012
Maria Nicolà D'Errico; G. De Tullio; M. Di Gioacchino; Piero Lovreglio; Antonella Basso; Ignazio Drago; R. Serra; Pietro Apostoli; Angelo Vacca; Leonardo Soleo
Polychlorinated biphenyls (PCB) have been shown to exert some immune effects. Here we analysed their effects also on immune parameters not previously studied such as TCR α-β, TCR γ-δ and regulatory T cells (Treg), taking into account the specific and cumulative interference of smoking and alcohol. The study subjects consisted of 26 male workers in a steelworks factory, employed in the electrical maintenance sector, with previous exposure to a mixture of PCB (exposed subjects), and 30 male workers with no occupational exposure to PCB (controls). All subjects were given a questionnaire and peripheral venous blood samples were taken to determine serum PCB (33 congeners), total cholesterol and triglycerides, leukocytes, total lymphocytes and the T lymphocyte subpopulations (TCR α-β, TCRγ-δ, CD4+ and Treg lymphocytes). PCB, even though at a very low concentration, were significantly higher in exposed subjects than controls, and were significantly correlated with age. Monocytes% and CD4+ were significantly reduced in the exposed subjects as compared to the controls. The serum concentration of PCB positively correlated with TCR α-β, and negatively with TCRγ-δ. Treg lymphocytes showed a positive dependence on tobacco smoking, while the monocytes% and CD4+ showed a negative and positive dependence, respectively, on alcohol intake. Our results seem to show some effects of slight exposure to PCB in particular reducing the relative concentration of TCRγ-δ. This effect can favour indirectly the increase in Treg induced by smoking, the anti-inflammatory or proinflammatory/fibrogenetic/angiogenetic effect of which, exerted by produced cytokines, particularly TGF-β, deserves further clarification.
Giornale italiano di medicina del lavoro ed ergonomia | 2011
Piero Lovreglio; Mariella Carrieri; Anna Barbieri; Laura Sabatini; Maria Enrica Fracasso; Denise Doria; Iavicoli S; Ignazio Drago; Maria Nicolà D'Errico; Imbriani M; Francesco Saverio Violante; Giovanni Battista Bartolucci; Leonardo Soleo
Giornale italiano di medicina del lavoro ed ergonomia | 2013
Piero Lovreglio; Mariella Carrieri; Anna Barbieri; Laura Sabatini; Silvia Fustinoni; Roberta Andreoli; Maria Nicolà D'Errico; Antonella Basso; Giovanni Battista Bartolucci; Leonardo Soleo
Giornale italiano di medicina del lavoro ed ergonomia | 2012
Leonardo Soleo; Piero Lovreglio; Panuzzo L; Maria Nicolà D'Errico; Antonella Basso; Me Gilberti; Ignazio Drago; Tomasi C; Pietro Apostoli
Medicina Del Lavoro | 2012
Piero Lovreglio; Maria Nicolà D'Errico; Paolo De Pasquale; Maria Enrica Gilberti; Ignazio Drago; Panuzzo L; Antonella Lepera; R. Serra; Francesco Ferrara; Pietro Apostoli; Leonardo Soleo
Giornale italiano di medicina del lavoro ed ergonomia | 2010
Piero Lovreglio; G. Cancanelli; Anna Barbieri; Laura Sabatini; Maria Nicolà D'Errico; L. Scicolone; Roberta Ghitti; Francesco Saverio Violante; Pietro Apostoli; Leonardo Soleo
Medicina Del Lavoro | 2013
Piero Lovreglio; Maria Nicolà D'Errico; Antonella Basso; Ferrara E; Panuzzo L; Pietro Apostoli; Leonardo Soleo
Medicina Del Lavoro | 2013
Piero Lovreglio; Maria Nicolà D'Errico; Antonella Basso; Francesco Ferrara; Panuzzo L; Pietro Apostoli; Leonardo Soleo
Giornale italiano di medicina del lavoro ed ergonomia | 2013
Leonardo Soleo; Emanuele Cannizzaro; Piero Lovreglio; Antonella Basso; Maria Nicolà D'Errico; Enrico Pira