Maria Talita Soares Frade

Systemic acanthamoebiasis associated with canine distemper in dogs in the semiarid region of Paraíba, Brazil

Infections by free-living amoebae can cause systemic disease in animals and humans. We describe the epidemiological, clinical and pathological aspects of disseminated acanthamoebiasis associated with canine distemper in three dogs of the semiarid region of Paraiba, Northeastern Brazil. Affected dogs developed progressive neurological and respiratory signs that progressed to death within in two to 20 days. Gross lesions were irregular and with yellow-reddish nodules randomly distributed in the lungs, heart, kidneys, spleen, lymph nodes, adrenals, and intestine. One dog had foci of malacia in the parietal cortex and another one in nucleus of brain basis. Histologically, pyogranulomas with areas of necrosis and hemorrhage in all organs affected were observed, associated with myriads of intralesional amoebic trophozoites. All three cases were concomitant canine distemper, that possibly triggered immunosuppression in the dogs. The diagnosis was performed through microscopic findings of infection by free-living amoebae and confirmed Acanthamoeba sp. by immunohistochemistry

Morte súbita causada por ruptura de aneurisma em aorta em ruminantes

ABSTRACT From a total of 2,088 necropsied ruminants in the Laboratory of Animal Pathology of Federal University of Campina Grande during the period from January 2003 to December 2015, 803 (38.45%) were cattle, 651 (31.18%) sheep, and 634 (30.37%) goats. Of these, two goats (0.31%), one sheep (0.15%) and one bovine (0.12%) were diagnosed with rupture of aorta due to the presence of aneurysms, corresponding to 0.19% of causes of death in ruminants. Case 1 occurred in a goat that had good body condition and was found dead by the owner, case 2 occurred in a goat that had clinical presumptive diagnosis of caseous lymphadenitis, case 3 occurred in a sheep who was found dead by the owner, and case 4 occurred in a cow with a history of recurrent bloating. In all cases, death occurred rapidly by hypovolemic shock. The macroscopic findings at necropsy were hemothorax or hemoperitoneum and the rupture in the aorta artery. In goats, abscesses were viewed microscopically and they were associated with the presence of bacteria, suggesting for