Mario Goessl

IMPACT OF THE COMMERCIAL INTRODUCTION OF TRANSCATHETER MITRAL VALVE REPAIR ON MITRAL SURGICAL PRACTICE

With the commercial introduction of transcatheter mitral valve repair with MitraClip into the U.S. in 2013, there has been uncertainty regarding the effect of this therapy on cardiac surgical practice. The present investigation was undertaken to examine the impact of this introduction in the context

TCT-667 Causes and Clinical Outcomes of Patients with Mitral Regurgitation Who are ineligible for Transcatheter Mitral Valve Replacement

Despite the increasing availability of transcatheter mitral valve replacement (TMVR) under research investigation, patients with mitral regurgitation (MR) frequently are not eligible for such therapy. The characteristics of these patients who fail qualification and their clinical outcomes are

TCT-738 Optimizing cost savings in minimalist transfemoral TAVR – closing the gap

METHODS Retrospective analysis of consecutive TAVR patients for whom pre procedural angles were predicted by cardiac imaging specialists using two methods: manual multiplanar reformations (MR) and the semi-automatic optimal angle graph (OAG). The distributions of predicted versus actual cranial caudal (CRA\CAU, Y axis) and right and left anterior oblique (RAO\LAO, X axis) angles are presented in scatter plots. Paired analysis was used to compare the distributions and means following definition of equal distribution as the null hypothesis. The difference between the two dimensional distributions and means were compared to a zero bivariate normal distribution and mean.

RETENTION OF OSTEOGENIC CD14–MONOCYTES WITHIN THE CORONARY CIRCULATION CORRELATES WITH CORONARY CALCIFICATION

Myeloid calcifying cells (from monocyte/macrophage linage expressing Osteocalcin [OCN+]) were found to play a major role in diabetic carotid atherosclerosis. We hypothesized a link between CD14+/OCN+–cells and degree of coronary calcification using virtual histology–intravascular ultrasound (VH

OSTEOCALCIN POSITIVE CD133p/CD34-/KDRp PROGENITOR CELLS ARE ASSOCIATED WITH POOR GLYCEMIC CONTROL

Vascular calcification, an important feature of diabetic vasculopathy, may be mediated by a sub-type of endothelial progenitor cells (EPCs) co-expressing the osteoblastic marker osteocalcin (OCN). In this study we tested the hypothesis that there is an association of these cells with HbA1c, a

OSTEOCALCIN POSITIVE CD133p/CD34-/KDRp PROGENITOR CELLS AS MARKERS OF CORONARY ARTERY DISEASE AND PROGNOSIS

CD133p/CD34-/KDRp cells may represent less mature progenitors than CD34p/KDRp cells. In patients with coronary artery disease (CAD), a large fraction of progenitors carry the osteoblastic marker osteocalcin, which may mediate vascular calcification and abnormal repair. We