Marissa Bolson Serafin

Células-tronco adultas no tratamento do diabetes mellitus tipo I: uma revisão de literatura

Objective - to clarify the applicability of cell therapy with adult stem cells in the treatment of type I diabetes mellitus in the national and international scenario. Methodology - exploratory descriptive bibliographic review, developed between March and October 2012. For this purpose, the databases Scielo, PubMed, Lilacs and Bireme were used, being considered original scientific articles published from 2002 to 2012. Results - five papers addressed the proposed theme, which presented the different cell therapy alternatives in type I diabetes mellitus worldwide. Conclusions - this study made it possible to conclude that the practice of cell therapy may be accessible to the entire population within a few years and has greater benefits than possible risks for the treatment of chronic diseases such as type I diabetes, providing improvements in the quality of life of patients. treated patients

RESISTÊNCIA À COLISTINA EM ISOLADOS DE HEMOCULTURAS DE RECÉM-NASCIDOS ADMITIDOS EM UM HOSPITAL ESCOLA

The objective of this study was to evaluate resistance against colistin in isolates of blood cultures from newborns (NB) admitted in a School Hospital in a 4-year period. The identification tests and antimicrobial susceptibility profiles were performed using automated systems. At the period of this study, 923 blood cultures were positive, 92.09% (850/923) were caused by Gram-positive microorganisms and 7.91% (73/923) by Gram-negative. Of these, two isolates were resistant to colistin: Acinetobacter baumannii and Sphingomonas paucimobilis; and a Pseudomonas aeruginosa isolate showed an intermediate profile to this antimicrobial, also presenting resistance to carbapenems. This profile is worrying since these antimicrobials are the last alternative for the treatment of infections caused by multiresistant Gram-negative bacilli. The results of this study indicate the follow-up of the monitoring of this resistance.