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Featured researches published by Marjolein A. M. Mulders.


Journal of Hand Surgery (European Volume) | 2017

Analysis of variation in the surgical treatment of patients with distal radial fractures in the Netherlands

Monique M. J. Walenkamp; Marjolein A. M. Mulders; J. C. Goslings; G. P. Westert; N.W.L. Schep

The purpose of this study was to examine the variation in surgical treatment rates of patients with distal radius fractures across Dutch hospitals. We obtained all reimbursement data for the treatment of distal radius fractures for 2012 and 2013 categorized by hospital. The surgical rate across hospitals was corrected for possible explanatory variables using linear regression analyses. We analysed a total of 95,754 reimbursements. The operative rate ranged from 0% to 23%, with a mean of 9.6%. Hospital type, the percentage of females, the percentage of patients over 65, the mean age, average socioeconomic status and the total number of patients treated explained only 2.6% of the observed differences in the operative rate among hospitals in 2012 and 11.6% in 2013. Our results suggest that subjective factors, such as surgeon’s opinions and preferences, significantly influence therapeutic decisions in patients with distal radius fractures. Level of evidence: III


Injury-international Journal of The Care of The Injured | 2017

Corrective osteotomy is an effective method of treating distal radius malunions with good long-term functional results

Marjolein A. M. Mulders; P.N. d’Ailly; B.I. Cleffken; N.W.L. Schep

INTRODUCTION Malunion occurs in approximately 23% of non-operatively treated and 11% of operatively treated distal radius fractures. The decision whether to correct a malunion is primarily based on functional impairment and wrist pain. The purpose of this study was to assess the long-term functional outcomes of corrective osteotomies for symptomatic malunited distal radius fractures. METHODS All consecutive corrective osteotomies of the distal radius performed in one centre between January 2009 and January 2016 were included. The primary outcome was the functional outcome assessed with the Disability of the Arm, Shoulder and Hand (DASH) and the Patient-Rated Wrist Evaluation (PRWE) score. Secondary outcomes were range of motion, grip strength, pain as indicated on the Visual Analogue Scale (VAS) before and after corrective osteotomy, radiological parameters, time to union and complications. Additionally, we aimed to determine if there were any difference in graft versus no graft usage. RESULTS A total of 48 patients were included. The median age was 54.5 years (IQR 39-66) and 71% was female. The median time to follow-up was 27 months. The median DASH and PRWE score were respectively 10.0 (IQR 5.8-23.3) and 18.5. (6.5-37.0). Except for pronation and supination, range of motion and grip strength of the injured wrist were significantly less compared to the uninjured side. Palmar and dorsal flexion and radial and ulnar deviation of the injured wrist were significantly less compared with the uninjured side. VAS pain scores decreased significantly from 6.5 preoperative to 1.0 postoperative. The median time to union was 23 weeks (IQR 12-29.5). Eighteen patients (38%) had a complication for which additional treatment was required. Except for a significant difference in radial inclination and length after the corrective osteotomy in favour of graft usage, there were no significant differences between graft an no graft usage. CONCLUSIONS Corrective osteotomy is an effective method of treating symptomatic distal radius malunions with good long-term functional results, measured with the DASH and PRWE score, and improvement in radiographic parameters and pain scores. Additionally, no differences in functional outcomes were found between graft and no graft usage.


Acta Orthopaedica | 2017

Normative data for the lower extremity functional scale (LEFS)

Siem A. Dingemans; Suzanne C. Kleipool; Marjolein A. M. Mulders; Jasper Winkelhagen; N.W.L. Schep; J. Carel Goslings; Tim Schepers

Background and purpose — The lower extremity functional scale (LEFS) is a well-known and validated instrument for measurement of lower extremity function. The LEFS was developed in a group of patients with various musculoskeletal disorders, and no reference data for the healthy population are available. Here we provide normative data for the LEFS. Methods — Healthy visitors and staff at 4 hospitals were requested to participate. A minimum of 250 volunteers had to be included at each hospital. Participants were excluded if they had undergone lower extremity surgery within 1 year of filling out the questionnaire, or were scheduled for lower extremity surgery. Normative values for the LEFS for the population as a whole were calculated. Furthermore, the influence of sex, age, type of employment, socioeconomic status, and history of lower extremity surgery on the LEFS were investigated. Results — 1,014 individuals fulfilled the inclusion criteria and were included in the study. The median score for the LEFS for the whole population was 77 (out of a maximum of 80). Men and women had similar median scores (78 and 76, respectively), and younger individuals had better scores. Participants who were unfit for work had worse scores. There were no statistically significant correlations between socioeconomic status and type of employment on the one hand and LEFS score on the other. A history of lower extremity surgery was associated with a lower LEFS score. Interpretation — High scores were observed for the LEFS throughout the whole population, although they did decrease with age. Men had a slightly higher score than women. There was no statistically significant correlation between socioeconomic status and LEFS score, but people who were unfit for work had a significantly worse LEFS score.


Trials | 2018

Operative Treatment of Intra-Articular Distal Radius Fractures With versus Without Arthroscopy: study protocol for a randomised controlled trial

Marjolein A. M. Mulders; Caroline A. Selles; Joost W. Colaris; Rolf W. Peters; Mark van Heijl; Berry I. Cleffken; N.W.L. Schep

BackgroundIn the past several years, an increase in open reduction and internal fixation (ORIF) for intra-articular distal radius fractures has been observed. This technique leads to a quicker recovery of function compared to non-operative treatment. However, some patients continue to have a painful and stiff wrist postoperatively. Arthroscopically assisted removal of intra-articular fracture haematoma and debris may improve the functional outcomes following operative treatment of intra-articular distal radius fractures. The purpose of this randomised controlled trial is to determine the difference in functional outcome, assessed with the Patient-Rated Wrist Evaluation (PRWE) score, after ORIF with and without an additional wrist arthroscopy in adult patients with displaced complete articular distal radius fractures.MethodsIn this multicentre trial, adult patients with a displaced complete articular distal radius fracture are randomised between ORIF with an additional wrist arthroscopy to remove fracture haematoma and debris (intervention group) and conventional fluoroscopic-assisted ORIF (control group). The primary outcome is functional outcome assessed with the PRWE score after three months. Secondary outcomes are wrist function assessed with the Disability of the Arm, Shoulder and Hand (DASH) score, postoperative pain, range of motion, grip strength, complications and cost-effectiveness. Additionally, in the intervention group, the quality of reduction, associated ligamentous injuries and cartilage damage will be assessed. A total of 50 patients will be included in this study.DiscussionAlthough ORIF of intra-articular distal radius fractures leads to a quicker resume of function compared to non-operative treatment, some patients continue to have a painful and stiff wrist postoperatively. We hypothesise that, due to the removal of fracture haematoma and debris by an additional arthroscopy, functional outcomes will be better compared to the non-arthroscopically treated group.Trial registrationClinicalTrials.gov, NCT02660515. Registered on 13 January 2016.


Pediatric Radiology | 2017

Erratum to: External validation of clinical decision rules for children with wrist trauma

Marjolein A. M. Mulders; Monique M. J. Walenkamp; Bente F. H. Dubois; Annelie Slaar; J. Carel Goslings; N.W.L. Schep

The published version of this article contained mistakes. Table 6 was published with incorrect table heading and table legend. This has now been corrected.


BMC Musculoskeletal Disorders | 2016

Internal plate fixation versus plaster in displaced complete articular distal radius fractures, a randomised controlled trial

Marjolein A. M. Mulders; Monique M. J. Walenkamp; J. Carel Goslings; N.W.L. Schep


European Journal of Trauma and Emergency Surgery | 2017

Classification and treatment of distal radius fractures: a survey among orthopaedic trauma surgeons and residents

Marjolein A. M. Mulders; Daniel A. Rikli; J. C. Goslings; N.W.L. Schep


Strategies in Trauma and Limb Reconstruction | 2017

Repair of the pronator quadratus after volar plate fixation in distal radius fractures: a systematic review

Marjolein A. M. Mulders; Monique M. J. Walenkamp; Fernande J.M.E. Bos; N.W.L. Schep; J. Carel Goslings


Pediatric Radiology | 2017

External validation of clinical decision rules for children with wrist trauma (vol 47, pg 590, 2017)

Marjolein A. M. Mulders; Monique M. J. Walenkamp; Bente F. H. Dubois; Annelie Slaar; J. Carel Goslings; N.W.L. Schep


Injury-international Journal of The Care of The Injured | 2016

OS4-32 Long-term functional outcomes after corrective osteotomy of distal radius malunions

Marjolein A. M. Mulders; P. d'Ailly; B.I. Cleffken; N.W.L. Schep

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N.W.L. Schep

Academic Medical Center

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G. P. Westert

Radboud University Nijmegen

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Joost W. Colaris

Erasmus University Rotterdam

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