Mary Louise Mandich

External source Fourier transform ion cyclotron resonance mass spectrometry by using a split-pair magnet

Abstract A new instrument has been designed, built, and tested for high performance Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS) that allows operation at gas pressures of up to ∼20 Torr in the ion source and up to ∼0.01 Torr in the ion trap. FTICRMS performance is not compromised at these pressures due to an external, high throughput ion source and pulsed gas introduction/rapid gas evacuation of the vacuum chamber at the trapped ion cell. This system is the first to retain ions at 0.01-Torr gas pressure in the ion trap with high sensitivity. This performance is achieved while obtaining high mass resolution and ppm mass accuracies.