Masahiko Kusunose
Kindai University
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Publication
Featured researches published by Masahiko Kusunose.
Journal of Pharmacy and Pharmacology | 2007
Guangchen Sun; Yixiu Zhang; Daisuke Takuma; Masahide Onogawa; Junko Yokota; Atsuhide Hamada; Saburo Yoshioka; Masahiko Kusunose; Mitsuhiko Miyamura; Shojiro Kyotani; Yutaka Nishioka
The anti‐allergic activity of Eriobotrya japonica seeds extract (ESE) was investigated. Oral administration of ESE dramatically inhibited ear swelling due to allergic contact dermatitis caused by repeated application of two antigens, 4‐ethoxymethylene‐2‐phenyl‐2‐oxazolin‐5‐one (oxazolone) and dinitrofluorobenzene (DNFB), respectively. The increase of histamine content in inflamed ear tissue induced by oxazolone and DNFB was significantly antagonized by orally administered ESE. Eosinophil peroxidase and myeloperoxidase activity in both models was suppressed by orally administered ESE. Tumour necrosis factor‐α in the inflamed region caused by repeated application of DNFB was also significantly suppressed. The findings suggest that ESE may be effective for treating allergic contact dermatitis.
Journal of Pharmacy and Pharmacology | 2009
Masahide Onogawa; Guangchen Sun; Daisuke Takuma; Atsuhide Hamada; Junko Yokota; Saburo Yoshioka; Masahiko Kusunose; Mitsuhiko Miyamura; Shojiro Kyotani; Yutaka Nishioka
Objectives The potent antioxidant activity of Eriobotrya japonica seed extract (ESE) and its usefulness in the prevention and treatment of various disorders has been reported previously. Its antioxidant activity associated with β‐sitosterol and polyphenols contained in the extract was also validated. In this study, anti‐allergic activity of Eriobotrya japonica seed extract was investigated.
Biological & Pharmaceutical Bulletin | 2004
Mitsuhiko Miyamura; Saburo Yoshioka; Atsuhide Hamada; Daisuke Takuma; Junko Yokota; Masahiko Kusunose; Shojiro Kyotani; Hirohisa Kawakita; Kazuhiro Odani; Yasuyuki Tsutsui; Yutaka Nishioka
Biological & Pharmaceutical Bulletin | 2003
Saburo Yoshioka; Atsuhide Hamada; Tailin Cui; Junko Yokota; Sayaka Yamamoto; Masahiko Kusunose; Mitsuhiko Miyamura; Shojiro Kyotani; Ryou Kaneda; Yasuyuki Tsutsui; Kazuhiro Odani; Ichiro Odani; Yutaka Nishioka
Biological & Pharmaceutical Bulletin | 2006
Junko Yokota; Daisuke Takuma; Atsuhide Hamada; Masahide Onogawa; Saburo Yoshioka; Masahiko Kusunose; Mitsuhiko Miyamura; Shojiro Kyotani; Yutaka Nishioka
Biological & Pharmaceutical Bulletin | 2004
Atsuhide Hamada; Saburo Yoshioka; Daisuke Takuma; Junko Yokota; Tailine Cui; Masahiko Kusunose; Mitsuhiko Miyamura; Shojiro Kyotani; Yutaka Nishioka
Biological & Pharmaceutical Bulletin | 2002
Masahiko Kusunose; Bing Qiu; Tailin Cui; Atsuhide Hamada; Saburo Yoshioka; Masahide Ono; Mitsuhiko Miyamura; Shojiro Kyotani; Yutaka Nishioka
Biological & Pharmaceutical Bulletin | 2002
Yutaka Nishioka; Saburo Yoshioka; Masahiko Kusunose; Tailin Cui; Atuhide Hamada; Masahide Ono; Mituhiko Miyamura; Shojiro Kyotani
Chemical & Pharmaceutical Bulletin | 1992
Yutaka Nishioka; Shojiro Kyotani; Mituhiko Miyamura; Masahiko Kusunose
Biological & Pharmaceutical Bulletin | 2003
Tailin Cui; Masahiko Kusunose; Atsuhide Hamada; Masahide Ono; Mitsuhiko Miyamura; Saburo Yoshioka; Shojiro Kyotani; Yutaka Nishioka
