Masayuki Takamoto

A novel amino acid antibiotic tan-950

Abstract A novel antifungal antibiotic, TAN-950 A, was isolated from the culture filtrate of Streptomyces platensis A-136. Its structure was determined to be (S)-2-amino-3-(isoxazolin-5-on-4-yl)-propanoic acid. Minor components, TAN-950 B, C, D and E, were found to be present in an equilibrium mixture containing TAN-950 A. Their structures were determined from spectral analyses. X-ray crystallographic analysis and synthesis from L-glutamic acid.

Molecular conformation of thyrotropin-releasing hormone from the X-ray structural analysis of its tartrate

An X-ray crystal study of thyrotropin-releasing hormone tartrate has revealed that its molecular structure, in contrast with predictions based on energy calculations and n.m.r. spectroscopic studies, contains an extended peptide bond stabilized by a hydrogen bond between the π-NH unit of histidine and the carbonyl oxygen of the proline amide.

X ray crystallography of (+)-(R)p methyl phenyl phosphoramidate of ethyl L-phenylalaninate

Abstract The absolute configuration of (+)-(R) p methyl phenyl phosphoramidate of ethyl L-phenylalaninate 1 was determined by X ray crystallography.

A general synthesis of dibenz[C,F]-1-aza-bicyclo[3.3.1]-nonane and its related compounds

Aus den N,N-Dibenzyl-aminoacetaldehydacetalen (I) erhalt man mit ′ Perchlorsaure die Cyclisierungsprodukte (II).

X-Ray crystal structure of (E,E)-[2.4]paracyclophane-1,17-diene

The molecular structure of (E,E)-[2.4] paracyclophane-1,17-diene, a unique paracyclophane analogue, was established by an X-ray crystal structure analysis, and found to be of 2/m molecular symmetry with all benzene rings and vinylene groups perpendicular to molecular ring.