Megumi Mizuno
Kyoto University
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Publication
Featured researches published by Megumi Mizuno.
Atherosclerosis | 1996
Naoki Matsuoka; Hisato Jingami; Hiroaki Masuzaki; Megumi Mizuno; Shigeo Nakaishi; Junko Suga; Tokuji Tanaka; Tokuo Yamamoto; Kazuwa Nakao
To elucidate the regulation of very low density lipoprotein (VLDL) receptor gene expression, we administered to rabbits for 14 days gemfibrozil, a fabric acid derivative and a lipid lowering drug that is also included among peroxisome proliferators. VLDL receptor mRNA levels were examined by Northern blot analysis. The VLDL receptor mRNA levels in retroperitoneal adipose tissue and in gastrocnemius muscle were increased 6.9-fold and 3.7-fold, respectively, with gemfibrozil treatment, but no marked changes were observed in the heart, the organ in which VLDL receptor is most highly expressed. In the liver, VLDL receptor mRNA was not detected either before or after gemfibrozil administration. Lipoprotein lipase (LPL) and long-chain acyl coenzyme A synthetase (ACS) mRNA levels were also increased in parallel in adipose tissue. The enhanced expression of VLDL receptor mRNA may contribute to the increase of triglyceride-rich lipoprotein catabolism in peripheral tissues such as adipose tissue and muscles.
Applied Physics Letters | 2006
Masahide Takahashi; Masanori Saito; Megumi Mizuno; Hiroshi Kakiuchida; Yomei Tokuda; Toshinobu Yoko
Microstructures were fabricated by a photothermal process in a low-melting organic-inorganic hybrid material of tin silicophosphate doped with Nd3+ ion as a light absorber. The negative refractive index change of the order of 10−3 was photothermally induced inside the low-melting glass with a spatial resolution ranging from 10to100μm using a 514.5nm emission from an Ar+ laser of less than 30mW as the excitation source. The volume expansion due to the photogenerated heat at the laser focus is found to be responsible for the photothermally induced negative photorefractive index change.
Clinical and Experimental Pharmacology and Physiology | 1995
Hisato Jingami; Hiroaki Masuzaki; Naoki Matsuoka; Osamu Nakagawa; Yoshihiro Ogawa; Megumi Mizuno; Tokuo Yamamoto; K. Nakao
1. To elucidate the functional implication of very low density lipoprotein (VLDL) receptor, we studied the gene expression of VLDL receptor in rats. The VLDL receptor mRNA was highly expressed in the cardiac ventricle and skeletal muscle. Intermediate amounts of VLDL receptor mRNA were detected in adipose tissue, adrenal gland, brain and lung. Thus the tissue distribution of VLDL receptor mRNA in rats was similar to that reported previously in rabbits.
Journal of the American Ceramic Society | 2005
Megumi Mizuno; Masahide Takahashi; Taigo Takaishi; Toshinobu Yoko
Chemistry of Materials | 2006
Megumi Mizuno; Masahide Takahashi; Yomei Tokuda; Toshinobu Yoko
Journal of Solid State Chemistry | 2006
Bouzid Menaa; Megumi Mizuno; Masahide Takahashi; Yomei Tokuda; Toshinobu Yoko
Journal of Sol-Gel Science and Technology | 2007
Megumi Mizuno; Masahide Takahashi; Yomei Tokuda; Toshinobu Yoko
Journal of Materials Research | 2006
Megumi Mizuno; Masahide Takahashi; Toshinobu Yoko
Journal of The Japan Society of Powder and Powder Metallurgy | 2005
Megumi Mizuno; Hiroshi Kakiuchida; Masahide Takahashi; Yomei Tokuda; Toshinobu Yoko
Advances in Glass and Optical Materials II: Ceramic Transactions Series, Volume 197 | 2011
Bouzid Menaa; Megumi Mizuno; Masahide Takahashi; Yomei Tokuda; Toshinobu Yoko
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National Institute of Advanced Industrial Science and Technology
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