Mei-Xin Zhao

The Chemistry of the Morita-Baylis-Hillman Reaction

Morita-Baylis-Hillman Reaction Catalytic System for the Morita-Baylis-Hillman Reaction Transformations of Functional Groups in Morita-Baylis-Hillman Adducts Morita-Baylis-Hillman Adducts or Derivatives for the Construction of Cyclic Frameworks The application of Morita-Baylis-Hillman Reaction for the Synthesis of Natural Products

Synthesis of axially chiral oxazoline–carbene ligands with an N-naphthyl framework and a study of their coordination with AuCl·SMe2

Summary Axially chiral oxazoline–carbene ligands with an N-naphthyl framework were successfully prepared, and their coordination behavior with AuCl·SMe2 was also investigated, affording the corresponding Au(I) complexes in moderate to high yields.

Chapter 3:Transformations of Functional Groups in Morita–Baylis–Hillman Adducts

This chapter will mainly describe the transformations of hydroxyl group in MBH adducts and the MBH adducts related Friedel-Crafts reaction, isomerization, Heck reaction, hydrogenation, Diels-Alder reaction as well as a variety of nucleophilic additions such as carbon nucleophiles, nitrogen nucleophiles and so on. Moreover, radical reaction and metathesis reaction of MBH adducts will also be discussed.

Chapter 2:Catalytic Systems for the Morita–Baylis–Hillman Reaction

A remarkable number of effective catalysts have been identified and developed for Morita-Baylis-Hillman reaction and its asymmetric version. This Chapter will discuss achiral or chiral catalytic systems for the Morita-Baylis-Hillman reaction, which include amine-catalyzed system, phosphine-catalyzed system, Lewis acids-catalyzed system, co-catalyzed system, as well as polymer supported catalysts.

Chapter 1:Morita–Baylis–Hillman Reaction

This Chapter will describe the origin and growth of Morita-Baylis-Hillman reaction, the reactant classes and reaction conditions, and also discuss the general catalytic mechanisms.