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Dive into the research topics where Melinda S. Fraiser is active.

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Featured researches published by Melinda S. Fraiser.


Archive | 1992

Enhanced Signal Generation by Target Amplification

Rüdiger Rüger; David Segev; Michael C. Little; James G. Nadeau; G. Terrance Walker; James L. Schram; Melinda S. Fraiser; Amy Alexander; Douglas P. Malinowski; George H. Shimer; Keith C. Backman; E. James; Erko Stackebrandt; Werner Liesack

The polymerase chain reaction (PCR) represents the most common and widespread method for the direct amplification of specific sequences of nucleic acid target molecules. The basic reaction is comprised of three steps: 1. Denaturation of the target DNA 2. Annealing of sequence specific primers 3. Template-specific elongation of these primers with a DNA polymerase and desoxynucleotides


Archive | 1995

Strand displacement amplification using thermophilic enzymes

Melinda S. Fraiser; Catherine A. Spargo; George Terrance Walker; Mark Van Cleve; David James Wright; Michael C. Little


Archive | 1994

Decontamination of nucleic acid amplification reactions using uracil-N-glycosylase (UDG)

Melinda S. Fraiser; George Terrance Walker; James L. Schram


Archive | 1994

Decontamination of nucleic acid amplification reactions

Melinda S. Fraiser; George Terrance Walker; James L. Schram


Archive | 1993

Exonuclease decontamination method

Melinda S. Fraiser; James L. Schram; George Terrance Walker


Archive | 1996

Nicking of DNA using boronated nucleotides

Melinda S. Fraiser; George Terrance Walker


Archive | 1992

Probes to chlamydia trachomatis

Douglas P. Malinowski; Melinda S. Fraiser; Stewart Russell Jurgensen


Archive | 1998

Replication of nucleic acids using single-strand DNA binding proteins

Melinda S. Fraiser


Archive | 1997

Strand displacement amplification using boronated nucleotides

Melinda S. Fraiser; George Terrance Walker


Biologicals | 1996

DETECTION OF MYCOBACTERIUM TUBERCULOSIS BY THERMOPHILIC STRAND DISPLACEMENT AMPLIFICATION

Melinda S. Fraiser; C.M. Nycz; Catherine A. Spargo; Patricia Anne Spears; M. Van Cleve; T. Walker; David James Wright

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