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Melissa R. Miller

Johns Hopkins University School of Medicine

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Featured researches published by Melissa R. Miller.

British Journal of Pharmacology | 2015

Identification and optimization of 2‐aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels

Yingmin Zhu; Yungang Lu; Chunrong Qu; Melissa R. Miller; Jinbin Tian; Dhananjay P. Thakur; Jinmei Zhu; Zixin Deng; Xianming Hu; Meng Wu; Owen B. McManus; Min Li; Xuechuan Hong; Michael X. Zhu; Huai-Rong Luo

Transient receptor potential canonical (TRPC) channels play important roles in a broad array of physiological functions and are involved in various diseases. However, due to a lack of potent subtype‐specific inhibitors the exact roles of TRPC channels in physiological and pathophysiological conditions have not been elucidated.

Biophysical Journal | 2018

Human Sperm Rotation is Regulated by Asymmetrically Positioned Flagellar Control Units

Nadja Mannowetz; Melissa R. Miller; Samuel J. Kenny; Steven A. Mansell; Michal Wojcik; Robert S. Zucker; Ke Xu; Polina V. Lishko

Author(s): Mannowetz, Nadja; Miller, Melissa R; Kenny, Samuel J; Mansell, Steven A; Wojcik, Michal; Zucker, Robert S; Xu, Ke; Lishko, Polina V

Archive | 2013

ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel

Beiyan Zou; Daniel P. Flaherty; Denise S. Simpson; Brooks E. Maki; Melissa R. Miller; Jie Shi; Meng Wu; Owen B. McManus; Jennifer E. Golden; Jeffrey Aubé; Min Li

Archive | 2013

Development of a Selective Chemical Inhibitor for the Two-Pore Potassium Channel, KCNK9

Melissa R. Miller; Beiyan Zou; Jie Shi; Daniel P. Flaherty; Denise S. Simpson; Tuanli Yao; Brooks E. Maki; Victor W. Day; Justin T. Douglas; Meng Wu; Owen B. McManus; Jennifer E. Golden; Jeffrey Aubé; Min Li

Archive | 2011

Novel Chemical Inhibitor of TRPC4 Channels

Melissa R. Miller; Jie Shi; Meng Wu; Julie L. Engers; Corey R. Hopkins; Craig W. Lindsley; James M. Salovich; Yingmin Zhu; Jinbin Tian; Michael X. Zhu; Owen B. McManus; Min Li

Biochimica et Biophysica Acta | 2012

Autonomous transmembrane segment S4 of the voltage sensor domain partitions into the lipid membrane

Venkataswarup Tiriveedhi; Melissa R. Miller; Peter Butko; Min Li

Archive | 2013

Table 2, Targets from Ricerca profiling that showed > 50% inhibition

Archive | 2013

Figure 8, Structure and literature and MLPCN determined potency and selectivity data for C23

Beiyan Zou; Daniel P. Flaherty; Denise S. Simpson; Brooks E. Maki; Melissa R. Miller; Jie Shi; Meng Wu; Owen B. McManus; Jennifer E. Golden; Jeffrey Aubé; Min Li

Archive | 2013