Tuanli Yao

Synthesis of isocoumarins and α-pyrones via iodocyclization

Abstract A variety of 3-substituted 4-iodoisocoumarins and 6-substituted 5-iodo-2(2 H )-pyranones are readily prepared in excellent yields under mild reaction conditions by the reaction of o -(1-alkynyl)benzoates and ( Z )-2-alken-4-ynoates with ICl.

Regio- and Stereoselective Synthesis of Cyclic Imidates via Electrophilic Cyclization of 2-(1-Alkynyl)benzamides. A Correction

The electrophilic cyclization of 2-(1-alkynyl)benzamides affords high yields of cyclic imidates, instead of the previously reported isoindolin-1-ones, where cyclization proceeds on the oxygen of the carbonyl group rather than the nitrogen of the amide functionality. X-ray crystallography and spectroscopic techniques have been used to characterize the products. A correction is hereby provided in order to rectify the previous misassignment of structure.