Melvin Gross

Diagnosis and treatment of neonatal adrenal hemorrhage

Summary Our experience with a small group of infants with adrenal hemorrhage has shown that the clinical course may vary depending upon the extent of the underlying hemorrhage and the presence or absence of adrenal insufficiency or infection. Increased awareness of the factors leading to adrenal hemorrhage and its subsequent complications should lead to early and prompt therapy. Depending upon the extent of the lesion and the ability to exclude neuroblastoma, therapy will range from nonoperative supportive therapy to immediate surgery.

Anuria Following Urography with Meglumine Diatrizoate (Renografin) in Multiple Myeloma

Only 11 cases of multiple myeloma with anuria attributable to urography have been documented. The agents used in the previous cases have been iodopyracet (Diodone and Diodrast), diodondiaethanolaminum (Nycotract), and sodium acetrizoate (Urokon Sodium) (1–10). This is the first reported case of anuria following the use of meglumine diatrizoate (Renografin) as the contrast medium. Case Report A normotensive 59-year-old Caucasian woman was admitted on March 8, 1967, with intermittent, severe lumbosacral pain of three weeks duration, urinary frequency, oral temperature of 101° F, and slight dehydration. Urinalysis revealed 1+ proteinuria, granular casts, and bacteriuria. Abdominal roentgenography demonstrated bilateral calcific densities opposite the lumbar vertebrae. Urography performed on March 9 with 50 cc of Renografin-60 (before the results of the renal function tests were obtained) showed nonvisualization of the collecting system. Laboratory determinations revealed a blood urea nitrogen of 130 mg per 1...