Meng-Yuan Jiang

Highly Functionalized Daphnane Diterpenoids from Trigonostemon thyrsoideum

Trigonothyrins A-C (1-3), which are highly functionalized daphnane diterpenoids, were isolated from the stems of Trigonostemon thyrsoideum. Compounds 1-3 represent the first examples of daphnanes with an oxygen-bridged four-membered-ring system, and a linkage mode of 12,13,14-orthoester. Compound 3 was observed to inhibit HIV-1 induced cytopathic effects. The EC(50) value was 2.19 microg/mL, and the therapeutic index (TI) was more than 90.

Speciosins A−K, Oxygenated Cyclohexanoids from the Basidiomycete Hexagonia speciosa

Eleven new oxygenated cyclohexanoids, speciosins A-K (1-11), and aporpinone A (12) were isolated from broth cultures of the basidiomycete Hexagonia speciosa. Their structures were elucidated on the basis of extensive spectroscopic analysis, while the structure of 8 was additionally confirmed by analysis of single-crystal X-ray diffraction data.

Purpuracolide: a New Alliacane Sesquiterpene from the Basidiomycete Gomphus purpuraceus

A new alliacane sesquiterpene named purpuracolide (1) was isolated from the fruiting bodies of basidiomycete Gomphus purpuraceus. The structure and stereochemistry have been established on the basis of spectroscopic data.

A new isoprenyl phenyl ether riboside from the culture of basidiomycete Laccaria amethystea.

A new isoprenyl phenyl ether riboside, 3-(3-methylbut-2-enyloxy)-4-O-α-d-ribofuranose benzoic acid methyl ester (1), was isolated from the culture of basidiomycete Laccaria amethystea. The structure of 1 was elucidated on the basis of extensive spectroscopic analysis.

Two New Metabolites from Basidiomycete Sparassis crispa

Two new metabolites, named crispacolide (1) and 3-acetyl-4-hydroxymethyl-tetrahydrofuran (2), were isolated from the fruiting bodies of basidiomycete Sparassis crispa (Wulf.) Fr. The structures and stereochemistry were established on the basis of spectroscopic means Graphical Abstract Two New Metabolites from Basidiomycete Sparassis crispa