Messaoud Hachemi

Applications of Microwave in Organic Synthesis: An Improved One-step Synthesis of Metallophthalocyanines and a New Modified Microwave Oven for Dry Reactions

Metallophthalocyanine complexes are obtained quickly and efficiently by the reaction of phthalodinitrile with hydrated metallic salts without solvent and under microwave irradiation. The use of a modified commercial microwave oven to perform this type of reactions under dry conditions is described. Metallophthalocyanines and metallododecachlorophthalocyanines of some divalent metals can be also obtained from phthalic or tetrachlorophthalic anhydrides with hydrated metallic salt and urea under microwave irradiation and without solvent.

Supported metalated phthalocyanine as catalyst for oxidation by molecular oxygen. Synthesis of quinones and carbonyl compounds

ABSTRACT Supported metalated phthalocyanine on K10 or on lamellar zirconium phosphate catalyses the oxidation of hydroquinones (and phenols) into quinones. Some interesting natural napthoquinones were also prepared (Juglone, Menadione, Lawsone, Phthiocol). Supported metalated phthalocyanine was also used in re-oxidation by oxygen of palladium and ruthenium, in the Wacker oxidation of olefins into ketones, in the oxidation of cyclohexadiene and in oxidation of benzylic alcohols in aldehydes.

Cesium Fluoride on Calcium Oxide as a Strongly Basic Catalyst. Synthesis of Flavones and Tobacco Alkaloids

CsF on CaO was used as a catalyst in the synthesis of flavones and their derivatives from esters of 2-hydroxyacetophenones and in the synthesis of tobacco alkaloids from aromatic amides.

An abnormal reaction of esters of 3-hydroxy-3-methylbutan-2-one. A rapid synthesis of bullatenone and geiparvarin

Abstract A new rapid and facile synthesis of two natural products with the structure of 3(2H)furanone is described by a cyclisation catalysed by cesium fluoride.

Potassium Fluoride on Alumina: A Convenient Synthesis of O-Alkyl Methyldithiocarbonates. Pyrolysis of O-Benzyl-S-Methyldithiocarbonates

Abstract Xanthates were easily prepared by adsorption of alcohol on KF-Al2O3 followed by treatment of carbon disulfide and iodomethane at room temperature. Pyrolysis of benzyl xanthate affords to a complex mixture of products. A radical process was proposed to explain the nature of products obtained.

Potassium Fluoride on Alumina: One-Pot Synthesis of N-Allyl Trichloroacetamides by Cascade Condensation-Sigmatropic Rearrangement

Abstract Allyl alcohols adsorbed on Al2O3-KF at room temperature reacted with trichloroacetonitrile and gave rearranged trichloroacetamides at room temperature, in one pot reaction.

Potassium Fluoride on Alumina: One-Pot Synthesis of S-Allyl-S-Methyldithiocarbonates by Tandem Condensation-Alkylation-Sigmatropic Rearrangement

Abstract Allyl alcohols adsorbed on Al2O3-KF at room temperature reacted with carbon disulfide and iodomethane and gave S-allyl-S-methyldithiocarbonate. Linalool did not give a rearrangement product. With chrysanthemyl alcohol, opening of the cyclopropane ring was observed.

A CONVENIENT SYNTHESIS OF CYCLOPROPANES FROM OLEFIN AND CARBON ACID COMPOUNDS. SYNTHESIS OF TETRAETHYL CYCLOPROPANEDIYLDIPHOSPHONATES

Abstract Cyclopropane were obtained from electron deficient olefins and acid carbon compounds by oxidation by iodine in the presence of KF on alumina. The reaction allows the synthesis of cyclopropanediyldiphosphonates.

Potassium Fluoride on Alumina: One-Pot Synthesis of Allyl Dithioesters by Tandem Condensation- Alkylation-Sigmatropic Rearrangement

Abstract Methylene ketones adsorbed on KF-alumina at room temperature react quickly with carbon disulfide and two equivalents of allyl chloride. The products undergo sigmatropic rearrangement, to give the corresponding allyl ketodithioesters.

DRY REACTION OF DIETHYL CYANOMETHYLPHOSPHONATE AND TETRAETHYL METHYLENEDIPHOSPHONATE WITH BENZALDEHYDE ON SOLID BASES

Abstract Competitive Horner and Knoevenagel reactions of benzaldehyde with diethyl cyanomethylphosphonate and tetraethyl methylenediphosphonate successively on different solid bases (oxide, fluoride and mixtures) without the use of solvent were investigated. Tetraethyl methylenediphosphonate with benzaldehyde with similar conditions gave only the product of Horners reaction. Basicity of the solid and nature of the cation (mono or divalent) of the base seemed important to explain the ratio of products formed in the Horner/Knoevenagel reactions.