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Dive into the research topics where Michael J. Postich is active.

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Featured researches published by Michael J. Postich.


Tetrahedron Letters | 1998

Practical synthesis of the anti-HIV drug, PMPA

Lisa M Schultze; Harlan H. Chapman; Nathan J.P. Dubree; Robert J. Jones; Kenneth M. Kent; Thomas T.K Lee; Michael S. Louie; Michael J. Postich; Ernest J. Prisbe; John C. Rohloff; Richard H. Yu

Abstract The anti-HIV nucleotide analogue PMPA can be prepared on a kilogram-scale by a three step sequence: i) condensation of adenine with ( R )-propylene carbonate, ii) alkylation of the resulting ( R )-9-(2-hydroxypropyl)adenine with diethyl p -toluenesulfonyloxymethanephosphonate using lithium tert -butoxide and iii) cleavage of the phosphonate ester functionalities with bromotrimethylsilane.


Journal of Organic Chemistry | 1998

PRACTICAL TOTAL SYNTHESIS OF THE ANTI-INFLUENZA DRUG GS-4104

John C. Rohloff; Kenneth M. Kent; Michael J. Postich; Mark W. Becker; Harlan H. Chapman; Daphne E Kelly; Willard Lew; Michael S. Louie; Lawrence R. McGee; Ernest J. Prisbe; Lisa M. Schultze; Richard H. Yu; Lijun Zhang


Journal of the American Chemical Society | 1992

Generation of 2-azaallyl anions by the transmetalation of N-(trialkylstannyl)methanimines. Pyrrolidine synthesis by [3 + 2] cycloadditions with alkenes

William H. Pearson; Daniel P. Szura; Michael J. Postich


Journal of Organic Chemistry | 1994

Approach to 6a-epipretazettine and 6a-epiprecriwelline via an intramolecular 2-azaallyl anion cycloaddition reaction

William H. Pearson; Michael J. Postich


Archive | 1997

Preparation of cyclohexene carboxylate derivatives

Kenneth M. Kent; Choung U. Kim; Lawrence R. McGee; John D Munger; Ernest J. Prisbe; Michael J. Postich; John C. Rohloff; Daphne E Kelly; Matthew A. Williams; Lijun Zhang


Archive | 1995

Thiepane compounds inhibiting and detecting hiv protease

Norbert Bischofberger; Choung U. Kim; Steven H. Krawczyk; Lawrence R. McGee; Michael J. Postich; Wenjin Yang


Journal of Organic Chemistry | 1992

An improved method for the preparation of pyrrolidines by the cycloaddition of nonstabilized 2-azaallyl anions with alkenes

William H. Pearson; Michael J. Postich


Photochemical Synthesis | 1997

Preparation of carbocyclic compounds

Kenneth M. Kent; Choung U. Kim; Lawrence R. McGee; John D Munger; Ernest J. Prisbe; Michael J. Postich; John C. Rohloff; Daphne E. St. John; Matthew A. Williams; Lijun Zhang


Journal of Organic Chemistry | 1989

Some mercuration reactions of substituted pyrroles

Jane A. Ganske; Ravindra K. Pandey; Michael J. Postich; Kevin M. Snow; Kevin M. Smith


Archive | 1997

Preparation de derives de cyclohexene carboxylate

Daphne E Kelly; Kenneth M. Kent; Choung U. Kim; Lawrence R. McGee; John D Munger; Michael J. Postich; Ernest J. Prisbe; John C. Rohloff; Matthew A. Williams; Lijun Zhang

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William H. Pearson

University of Wisconsin-Madison

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Richard H. Yu

University of Central Florida

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