Michael John Martinelli

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Featured researches published by Michael John Martinelli.

Tetrahedron Letters | 1988

Enynones in organic synthesis. I. Spiroannulation by tandem oxy-cope rearrangement-electrocyclic ring closure

Peter A. Jacobi; Lisa M. Armacost; Joseph I. Kravitz; Michael John Martinelli; Harold G. Selnick

Abstract Bis-acetylenic alcohols of proper design undergo a facile oxy-Cope rearrangement to afford mixtures of E- and Z-enynones. These latter compounds afford methylenecyclopentenones upon enolization and electrocyclic ring closure.

Tetrahedron Letters | 1988

Enynones in organic synthesis. II. An electron transfer mediated synthesis of methylenecyclopentenones

Peter A. Jacobi; Lisa M. Armacost; Joseph I. Kravitz; Michael John Martinelli

Abstract The electrocyclizaton of enynones to methylenecyclopentenones is markedly accelerated by phenols and catechols having a low oxidation potential.

Archive | 2002

Piperazine- and piperidine-derivatives as melanocortin receptor agonists

Karin Briner; Christopher William Doecke; Vincent Mancuso; Michael John Martinelli; Timothy I. Richardson; Roger Ryan Rothhaar; Qing Shi; Chaoyu Xie

Journal of the American Chemical Society | 1984

Total synthesis of (.+-.)-saxitoxin

Peter A. Jacobi; Michael John Martinelli; Slovenko Polanc

Journal of Organic Chemistry | 1998

An Enantioselective Synthesis of Cis Perhydroisoquinoline LY235959

Marvin M. Hansen; Carl Franklin Indianapolis Bertsch; Allen R. Harkness; Bret E. Huff; Darrell R. Hutchison; Vien V. Khau; Michael E. LeTourneau; Michael John Martinelli; Jerry W. Misner; Barry C. Peterson; John A. Rieck; Kevin A. Sullivan; Ian G. Wright

Archive | 2001

Triazole derivatives and their use as peroxisome proliferator activated receptor alpha agonists

David Scott Fishers Coffey; Cano Ivan Collado; Samuel J. Dominianni; Garret J. Etgen; Cristina Garcia-Paredes; Richard Duane Johnston; Michael E. LeTourneau; Nathan Bryan Mantlo; Michael John Martinelli; Daniel Ray Mayhugh; Ashraf Saeed; Christopher R. Schmid; Richard Craig Thompson; Jeffrey T. Vicenzi; Xiadong Wang; Yanping Xu

Journal of the American Chemical Society | 1981

A mild procedure for the generation of azomethine imines. Stereochemical factors in the intramolecular 1,3-dipolar addition of azomethine imines and a synthetic approach to saxitoxin

Peter A. Jacobi; Allen Brownstein; Michael John Martinelli; Karl Grozinger

Organic Process Research & Development | 2005

Nucleosidic phosphoramidite synthesis via phosphitylation : Activator selection and process development

Chaoyu Xie; Michael A. Staszak; John Thomas Indianapolis Quatroche; Christa D. Sturgill; Vien V. Khau; Michael John Martinelli

Journal of Organic Chemistry | 1994

Enynones in Organic Synthesis. 6. Synthesis of Spirocyclic Methylenecyclopentenones and Analogs of the Methylenomycin Class of Antibiotics. Mechanism of Phenol Catalysis

Peter A. Jacobi; Lisa M. Armacost; Harry L. Brielmann; Reginald O. Cann; Joseph I. Kravitz; Michael John Martinelli

Journal of Medicinal Chemistry | 1999

Fused bicyclic Gly-Asp β-turn mimics with specific affinity for GPIIb-IIIa

Matthew Fisher; Ann E. Arfstan; Ulrich Giese; Bruce P. Gunn; Cathy S. Harms; Vien V. Khau; Michael Dean Kinnick; Terry D. Lindstrom; Michael John Martinelli; Hans-Jürgen Mest; Michael Mohr; John Michael Morin; Jeffrey Thomas Mullaney; Anne Nunes; Michael Paal; Achim Rapp; Gerd Ruhter; Ken J. Ruterbories; Daniel Jon Sall; Robert M. Scarborough; Theo Schotten; Birgit Sommer; Wolfgang Stenzel; Richard D. Towner; Suzane L. Um; Barbara G. Utterback; Silke Vöelkers; Virginia L. Wyss; Joseph A. Jakubowski

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