Michihiro Sugano

(+)-Curcuphenol and dehydrocurcuphenol, novel sesquiterpenes which inhibit H,K-ATPase, from a marine sponge Epipolasis sp.

Two H, K-ATPase inhibitors and an inactive related compound have been isolated from a marine spongeEpipolasis sp. They are aromatic sesquiterpene α-curcumenes

H,K-ATPase inhibitors from the marine sponge siphonochalina truncata: Absolute configuration of siphonodiol and two related metabolites☆

Abstract Siphonodiol and two related metabolites were isolated from the marine sponge Siphonochalina truncata as H,K-ATPase inhibitors, and their structures including absolute configuration were determined by spectroscopic methods.

Sinulamide : an H, K-ATPase inhibitor from a soft coral Sinularia sp.

Sinulamide (1), a new tetraprenylated spermine derivative, has been isolated from a soft coral Sinularia sp. as an H,K-ATPase inhibitor. The structure was assigned on the basis of spectroscopic data and confirmed by a total synthesis.

Isolation of a hexaprenylhydroquinone sulfate from the marine sponge Dysidea sp. as an H,K-ATPase inhibitor

A hexaprenylhydroquinone sulfate has been isolated as an H, K-ATPase inhibitor from a marine spongeDysidea sp. It also inhibited phospholipase A2 as well as secretion of gastric acid in rats.

Aldose reductase inhibitors from the red alga, asparagopsis taxiformis.

Separation of an extract of the red alga Asparagopsis taxiformis guided by the inhibition of bovine lens aldose reductase gave pentabromopropen-2-yl tribromo-(1a) and dibromoacetate (1b), whose structures were determined by spectral data and chemical synthesis.