Mihai G. Netea
The Catholic University of America
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Publication
Featured researches published by Mihai G. Netea.
The Journal of Infectious Diseases | 1998
Bart Jan Kullberg; Mihai G. Netea; Jo H. A. J. Curfs; Monique Keuter; Jacques F. Meis; Jos W. M. van der Meer
The effect of recombinant granulocyte colony-stimulating factor (rG-CSF) on acute disseminated Candida albicans infection in nonneutropenic mice was investigated. Mice treated with a single dose of rG-CSF showed a significantly reduced mortality (28% vs. 90%; P < .001). The outgrowth of C. albicans from the kidneys, spleens, and livers of rG-CSF-treated mice was significantly reduced (log cfu/g of kidney, 5.54 vs. 7.13; P < .001), as were circulating tumor necrosis factor-alpha and interleukin-1beta. After rG-CSF, the kidneys showed fewer infectious infiltrates, enhanced granulocyte influx, and almost complete absence of hyphal outgrowth. During peritoneal C. albicans infection, rG-CSF enhanced influx of granulocytes to the site of infection, and exudate granulocytes showed increased oxygen radical production. These results indicate that rG-CSF enhances host resistance to disseminated candidiasis in nonneutropenic mice through activation of granulocytes and their recruitment to the site of infection.
Fems Immunology and Medical Microbiology | 1999
Bart Jan Kullberg; Mihai G. Netea; Alieke G Vonk; Jos W. M. van der Meer
The Journal of Infectious Diseases | 1999
Mihai G. Netea; Jos W. M. van der Meer; Jacques F. Meis; Bart Jan Kullberg
Virulence | 2010
W.J.F.M. van der Velden; Theo S. Plantinga; J.P. Donnelly; Bart-Jan Kullberg; N.M.A. Blijlevens; Mihai G. Netea
Archive | 2012
Theo S. Plantinga; M ontserrat Hervella; R osa Fregel; Jos W. M. van der Meer; Mihai G. Netea; Concepción de la Rúa
Archive | 2018
Rob J.W. Arts; Mihai G. Netea
18th European Congress of Endocrinology | 2016
Rob J.W. Arts; Theo S. Plantinga; Bas Heinhuis; Sander Tuit; Mirela Sanda Petrulea; Marika Tesselaar; Yvette Sloot; Benno Küsters; Leo A. B. Joosten; Carmen Emanuela Georgescu; Johannes W. A. Smit; Mihai G. Netea; Joakim Schulze; Romana T. Netea-Maier
Archive | 2012
Mihai G. Netea; Shih-Chin Cheng; Leo A. B. Joosten; Bart-Jan Kullberg
Archive | 2010
Walter J.F.M. van der Velden; Theo S. Plantinga; J. Peter Donnelly; Bart-Jan Kullberg; Mihai G. Netea
Archive | 2009
Robert J. Mason; Bart Jan Kullberg; Anna Rubartelli; Jos W. M. van der Meer; Frank L. van de Veerdonk; Gerben Ferwerda; Bas Heinhuis; Isabel Devesa; C. Joel Funk; Mihai G. Netea; Claudia A. Nold-Petry; Marcel F. Nold; Bastian Opitz