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Dive into the research topics where Milada Jankovska is active.

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Featured researches published by Milada Jankovska.


Leukemia & Lymphoma | 2014

Retrospective analysis of 235 unselected patients with mantle cell lymphoma confirms prognostic relevance of Mantle Cell Lymphoma International Prognostic Index and Ki-67 in the era of rituximab: long-term data from the Czech Lymphoma Project Database

David Šálek; Pavla Vesela; Ludmila Boudova; Andrea Janíková; Pavel Klener; Samuel Vokurka; Milada Jankovska; Robert Pytlik; David Belada; Jan Pirnos; Mojmír Moulis; Roman Kodet; Michal Michal; Eva Janoušová; Jan Muzik; Jiri Mayer; Marek Trněný

Abstract Although a prognostic model (MIPI, Mantle Cell Lymphoma International Prognostic Index) for patients with mantle cell lymphoma (MCL) has been established, its clinical significance for daily practice in the rituximab era remains controversial. Data of 235 unselected patients with MCL from the Czech Lymphoma Project Database were analyzed. MIPI, simplified MIPI (s-MIPI) and Ki-67 proliferation index were assessed for all patients and for a subgroup of 155 rituximab-treated (RT) patients. MIPI divided all patients into subgroups of low-risk (22%), intermediate-risk (29%) and high-risk (49%), with median overall survival 105.8 vs. 54.1 vs. 24.6 months, respectively (p < 0.001). s-MIPI revealed similar results. The validity of both indexes was confirmed in RT patients. We confirmed the Ki-67 index to be a powerful single prognostic factor for overall survival (64.4 vs. 20.1 months, p < 0.001) for all patients and for the RT subset. Our results confirm the clinical relevance of MIPI, s-MIPI and Ki-67 for risk stratification in MCL also in the rituximab era.


Blood | 2012

First Interim Efficacy and Safety Analysis of an International Phase III Randomized Trial in Newly Diagnosed Systemic Peripheral T-Cell Lymphoma Treated with Chemotherapy with or without Alemtuzumab and Consolidated by High Dose Therapy

Francesco d'Amore; Sirpa Leppä; Maria Comes da Silva; Thomas Relander; Peter Brown; Eckhart Weidmann; Grete F. Lauritzsen; Antonio Pezzutto; Achiel Van Hoof; Michel van Gelder; Jeanette K. Doorduijn; Ka Lung Wu; Johanna Kluin-Nelemans; Pieternella J. Lugtenburg; Milada Jankovska; Mats Merup; Unn-Merete Fagerli; Jan Walewski; Hans Hagberg; Jose Mario Mariz; Per Boye Hansen; Thomas Noesslinger; Ann Janssens; Lena Brandefors; Hilde Demuynck; Martyn Ronald Schaafsma; Ilse Christiansen; David Šálek; Sirkku Jyrkkiö; Vit Prochazka


Blood | 2011

First Interim Safety Analysis of a Phase III Randomized Trial in Newly Diagnosed Systemic Peripheral T-Cell Lymphoma Treated with CHOP Chemotherapy with or without Alemtuzumab and Consolidated by Autologous Hematopoietic Stem Cell Transplant

Francesco d'Amore; Maria Gomes da Silva; Sirpa Leppä; Thomas Relander; Antonio Pezzutto; Grete F. Lauritzsen; Eckhart Weidmann; Michel van Gelder; Mats Merup; Hans Hagberg; Unn-Merete Fagerli; Peter Brown; Per Boye Hansen; Jose Mario Mariz; Milada Jankovska; Jan Walewski; Jeanette K. Doorduijn; Achiel Van Hoof; Ilse Christiansen; Sirkku Jyrkkiö; Johanna Kluin-Nelemans; Marinus van Marwijk Kooy; Rob Fijnheer; W.B.C. Stevens; Josée M. Zijlstra; L. Bohmer; Pieternella J. Lugtenburg; Matthias Grube; Vit Prochazka; David Šálek


Blood | 2011

MicroRNA Analysis in the Cerebrospinal Fluid and Blood Serum of Lymphoma Patients At Diagnosis and in Response to Therapy

Vit Pospisil; Heidi Mocikova; Milada Jankovska; Jana Markova; Lubica Gaherova; Tomas Kozak; Tomas Stopka


Blood | 2010

Median Absolute Lymphocyte Count Independently Predicts Survival of Elderly Patients with Diffuse Large B-Cell Lymphoma Treated with R-Chemotherapy:Analysis of 651 Patients Included In the Czech Lymphoma Project

Vit Prochazka; Marek Trneny; David Šálek; David Belada; Tomas Kozak; Tomáš Papajík; Robert Pytlik; Ingrid Vášová; Alice Sykorova; Milada Jankovska; Katerina Kubackova; Martin Brejcha; Milan Matuska; Katarína Petráková; Jan Pirnos; J. Nepomucka; David Starostka; Milan Lysy; Vit Campr; Ludmila Boudova; Marie Trnkova; Marketa Petrova


Blood | 2006

Intensive Induction Is Beneficial for High Risk Younger Patients with Aggressive B-Cell Lymphoma, While Frontline ASCT Brings No Benefit: Final Analysis of MegaCHOP-BEAM and MegaCHOP-ESHAP-BEAM Studies.

Robert Pytlik; David Belada; Katerina Kubackova; Tomas Kozak; Milada Jankovska; Jan Pirnos; Ingrid Bolomska; Ingrid Vášová; Tomáš Papajík; Alena Sykorova; Hana Siffnerova; Michaela Hamouzova; Pavel Klener; Marek Trneny


Blood | 2004

Favorable Outcome of High-Risk Mediastinal Diffuse Large B-Cell Lymphoma (DLBCL) after Dose-Intensive Chemotherapy, Rituximab and Autologous Transplant (ASCT).

Robert Pytlik; Katerina Kubackova; Tomas Kozak; David Belada; Jan Pirnos; Milada Jankovska; J. Pukyova; Tomáš Papajík; Hana Siffnerova; P. Zak; Ingrid Vášová; Michaela Hamouzova; Marek Trneny


Blood | 2013

Frontline Intensive Chemotherapy Brings Survival Benefit In Young, Risky Patients With Follicular Lymphoma: Pair-Matched Analysis From The Czech Lymphoma Study Group (CLSG) Database

Marek Trneny; Andrea Janíková; David Belada; Tomas Kozak; Tomáš Papajík; Vit Campr; David Šálek; Robert Pytlik; Alice Sykorova; Milada Jankovska; Jitka Dlouha


Archive | 2010

Diagnostic and therapeutic approach to small lymphocyticlymphoma (SLL): experience of Czech lymphoma study group

Lukas Smolej; Ingrid Vášová; David Šálek; Jana Salkova; J. Karban; David Belada; Alice Sykorova; M. Spacek; Milada Jankovska; Vit Campr; Hana Krejcova; Marek Trneny


Archive | 2010

Diagnostika a léčba systémové mastocytózy.

Tomas Kozak; Michael Doubek; Jindřich Polívka; Milada Jankovska; Soňa Peková

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David Belada

Charles University in Prague

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Robert Pytlik

Charles University in Prague

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Tomas Kozak

Charles University in Prague

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Jan Pirnos

Charles University in Prague

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Marek Trneny

Charles University in Prague

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Vit Campr

Charles University in Prague

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Katerina Kubackova

Charles University in Prague

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Alice Sykorova

Charles University in Prague

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