Milton Louis Hoefle | Researchain

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Archive | 1984

Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis

Milton Louis Hoefle; Bruce D. Roth; Charlotte D. Stratton

Archive | 1981

Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids

Milton Louis Hoefle; Sylvester Klutchko

Journal of Medicinal Chemistry | 1986

Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types

Sylvester R. Klutchko; C. John Blankley; Robert W. Fleming; Jack M. Hinkley; Ann E. Werner; Ivan Nordin; Ann Holmes; Milton Louis Hoefle; David Cohen

Journal of Medicinal Chemistry | 1990

Inhibitors of cholesterol biosynthesis. 2. 1,3,5-trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles.

Drago R. Sliskovic; Bruce David Roth; Michael W. Wilson; Milton Louis Hoefle; Roger S. Newton

Journal of Medicinal Chemistry | 1975

Cardioselective beta-adrenergic blocking agents. 1. 1-((3,4-Dimethoxyphenethyl)amino)-3-aryloxy-2-propanols.

Milton Louis Hoefle; S. Hastings; Robert F. Meyer; Ruth M. Corey; Ann Holmes; Charlotte D. Stratton

Journal of Medicinal Chemistry | 1990

Inhibitors of cholesterol biosynthesis. 1. trans-6-(2-pyrrol-1-ylethyl)-4-hydroxypyran-2-ones, a novel series of HMG-CoA reductase inhibitors. 1. Effects of structural modifications at the 2- and 5-positions of the pyrrole nucleus.

Bruce David Roth; Daniel F. Ortwine; Milton Louis Hoefle; Charlotte D. Stratton; Drago R. Sliskovic; Michael William Wilson; Roger S. Newton

Journal of the American Chemical Society | 1960

Pyrimido [4,5-d]pyrimidines. Part I

Edward C. Taylor; Robert J. Knopf; Robert F. Meyer; Ann Holmes; Milton Louis Hoefle

Journal of Medicinal Chemistry | 1987

Synthesis and structure-activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids.

C. J. Blankley; James Stanley Kaltenbronn; D. E. Dejohn; A. Werner; Lawrence Ray Bennett; G. Bobowski; U. Krolls; Don Johnson; W. M. Pearlman; Milton Louis Hoefle; Arnold D. Essenburg; David Cohen; Harvey R. Kaplan

Journal of Medicinal Chemistry | 1981

Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors.

Robert F. Meyer; Ernest. Nicolaides; Francis G. Tinney; Elizabeth A. Lunney; Ann Holmes; Milton Louis Hoefle; Ronald D. Smith; Arnold D. Essenburg; Harvey R. Kaplan; Ronald G. Almquist

Journal of Medicinal Chemistry | 1982