Minoru Taguchi
Taisho Pharmaceutical Co.
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Publication
Featured researches published by Minoru Taguchi.
Bioorganic & Medicinal Chemistry Letters | 2003
Minoru Taguchi; Kikuo Sugimoto; Kenichi Goda; Tomoko Akama; Kyoko Yamamoto; Taizo Suzuki; Yasumitsu Tomishima; Mariko Nishiguchi; Koshi Arai; Kenzo Takahashi; Takeo Kobori
To search for neutral sphingomyelinase inhibitors we designed and synthesized hydrolytically stable analogues of sphingomyelin. The novel compounds 8 and 9 which were replaced the phosphodiester moiety of sphingomyelin with the carbamate moiety showed inhibitory activity with an IC(50) value of micro M on neutral sphingomyelinase in rat brain microsomes. Compound 8i showed a selective neutral sphingomyelinase inhibitory activity.
Bioorganic & Medicinal Chemistry Letters | 2003
Minoru Taguchi; Kenichi Goda; Kikuo Sugimoto; Tomoko Akama; Kyoko Yamamoto; Taizo Suzuki; Yasumitsu Tomishima; Mariko Nishiguchi; Koshi Arai; Kenzo Takahashi; Takeo Kobori
Chemical & Pharmaceutical Bulletin | 1995
Yutaka Kawashima; Akiyo Horiguchi; Minoru Taguchi; Yoshimi Tuyuki; Yasuko Karasawa; Hiroaki Araki; Katsuo Hatayama
Archive | 1992
Minoru Taguchi; Tomomi Ota; Katsuo Hatayama
Archive | 1998
Tomomi Ota; Misa Taisho Pharmace Nakanishi; Minoru Taguchi; Kazuyuki Tomisawa
Chemical & Pharmaceutical Bulletin | 1990
Morihiro Mitsukuchi; Tomoyuki Ikemoto; Minoru Taguchi; Shohei Higuchi; Satoshi Abe; Hajime Yasui; Katsuo Hatayama
Chemical & Pharmaceutical Bulletin | 1989
Morihiro Mitsukuchi; Tomoyuki Ikemoto; Minoru Taguchi; Shohei Higuchi; Satoshi Abe; Hajime Yasui; Katsuo Hatayama; Kaoru Sota
Archive | 2000
Kenichi Aida; Takeo Kobori; Kikuo Sugimoto; Minoru Taguchi; 賢一 合田; 武夫 小堀; 貴久男 杉本; 稔 田口
Chemical & Pharmaceutical Bulletin | 1989
Morihiro Mitsukuchi; Tomoyuki Ikemoto; Minoru Taguchi; Shohei Higuchi; Satoshi Abe; Hajime Yasui; Katsuo Hatayama; Kaoru Sota
Chemical & Pharmaceutical Bulletin | 1990
Morihiro Mitsukuchi; Tomoyuki Ikemoto; Minoru Taguchi; Shohei Higuchi; Satoshi Abe; Hajime Yasui; Katsuo Hatayama
