Mitsuyoshi Matsuo

Biosynthesis of skimmianine

Abstract Skimmianine isolated from Skimmia plants fed with anthranilic acid- 3 H, acetate-2- 14 C and DL-tryptophan-3- 14 C was shown to be radioactive. Degradation of the labeled skimmianine showed that the radioactivity was located in the benzene ring when anthranilic acid- 3 H was administered, while it was located at the position 3 of quinoline nucleus when acetate-2- 14 C or DL-tryptophan-3- 14 C was used as the labeled precursors. On the basis of these results, a scheme of the biosynthesis of skimmianine was proposed in which skimmianine was shown to be derived from anthranilic acid and acetate.

Biosynthesis of Sinigrin. IV. Syntheses of DL-Allylglycine (2-14C, 15N), DL-Homomethionine (2-14C, 15N), DL-Homomethionine (G-3H), 3-Methylthiopropionamide (1-14C) and 4-Methylthiobutyramide (1-14C)

The syntheses of DL-allylglycine (2-14C, 15N), DL-homomethionine (2-14C, 15N), DL-homomethionine (G-3H), 3-methylthiopropionamide (1-14C) and 4-methylthiobutyramide (1-14C) were described.