Mohsin Salih
University of Kentucky
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Publication
Featured researches published by Mohsin Salih.
American Journal of Cardiology | 2018
Aiman Smer; Mohsin Salih; Toufik Mahfood Haddad; Raviteja Guddeti; Abdulghani Saadi; Alok Saurav; Ram Belbase; Mohamed Ayan; Mahmoud Traina; Venkata Alla; Michael Del Core
The optimal management of patients with cryptogenic stroke (CS) and patent foramen ovale (PFO) remains controversial. We conducted a meta-analysis to assess the effect of PFO closure for secondary prevention of stroke on patients with CS. We searched the literature for randomized control trials assessing the recurrence of stroke after PFO closure compared with medical therapy (antiplatelet and/or anticoagulation). Five randomized control trials with a total of 3,440 patients were included. The mean age was 45.2 ± 9.7 years and follow-up duration ranged from 2.0 to 5.9 years. PFO closure significantly reduced the risk of stroke compared with the medical therapy (2.8% vs 5.8%; relative risk [RR] 0.48, confidence interval [CI] 0.27 to 0.87, p = 0.01, I2 = 56%). The number needed to treat for stroke prevention was 10.5. PFO closure was associated with an increased risk of atrial fibrillation compared with medical therapy (4.2% vs 0.7%; RR 4.55, CI 2.16 to 9.6, p = 0.0001, I2 = 25%). There was no significant difference in all-cause mortality (RR 1.33, CI 0.56 to 3.16, p = 0.52, I2 = 0%), as well as no difference in bleeding risk between the 2 groups (RR 0.94, CI 0.49 to 1.83, p = 0.86, I2 = 29%). In conclusion, our meta-analysis demonstrates that PFO closure is associated with significantly lower risk of recurrent stroke in patients with PFO and CS compared with medical therapy. However, atrial fibrillation was more common among closure patients.
Journal of the American College of Cardiology | 2015
Mohsin Salih; Yansoun Elmasry; Pedro Villablanca Spinetto; Hameem Kawsar; John C. Somberg
Antiplatelet agents are used for secondary prevention in patients with ischemic stroke or transient ischemic attack. Emerging studies suggest that early administration of dual antiplatelet therapy (DAPT) may be better than single antiplatelet therapy for the prevention of recurrent ischemic stroke,
Pacing and Clinical Electrophysiology | 2018
Yousef Darrat; Francis Benn; Mohsin Salih; Jignesh Shah; Kevin Parrott; Gustavo Morales; John C. Gurley; Claude-Samy Elayi
Subcutaneous implantable cardioverter defibrillators (S‐ICDs) have gained increasing popularity because of certain advantages over transvenous ICDs. However, while conventional ICDs require a single surgical incision to implant, S‐ICDS need two or three incisions, making them less appealing.
Clinical Cardiology | 2018
Aiman Smer; Mohsin Salih; Yousef Darrat; Abdulghani Saadi; Raviteja Guddeti; Toufik Mahfood Haddad; Amjad Kabach; Mohamed Ayan; Alok Saurav; Hussam Abuissa; Claude S. Elayi
The role of catheter ablation (CA) is increasingly recognized as a reasonable therapeutic option in patients with atrial fibrillation (AF) and heart failure (HF).
Baylor University Medical Center Proceedings | 2018
Mohamed Ayan; Zaid Gheith; Aneesha Ananthula; Mohsin Salih; Srikanth Vallurupalli; Jawahar L. Mehta
ABSTRACT The measurement of cardiac troponin, released from injured cardiomyocytes, is of paramount importance in the diagnosis of acute myocardial infarction. Elevated troponin can be encountered, however, in patients with cardiomyopathy, significant cardiac arrhythmias, vasculitis, right-sided heart strain, critical systemic illnesses, stroke, drug toxicity (such as Adriamycin), poisons (such as snake venoms), renal failure, seizure, and rhabdomyolysis. If the clinical picture is not consistent with any of these causes, a false-positive result should be considered. We herein describe a 94-year-old man with a prior history of coronary artery disease who presented with altered mental status and was found to have a persistently high troponin level resulting in three admissions to the coronary care unit for various noncardiac complaints. Because of discordance between clinical and laboratory data, immunological interference due to heterophile antibodies in the locally used assay (AccuTnI+3, Beckman Coulter) was suspected. The same serum sample tested on a different assay (Elecsys Troponin I Assay, Roche) resulted in an undetectable cardiac troponin I level, thus confirming the diagnosis.
Case Reports in Medicine | 2015
Aiman Smer; Osama Elsallabi; Mohamed Ayan; Haitam Buaisha; Hamza Rayes; Yazeid Alshebani; Hamza Tantoush; Mohsin Salih
Sinus of Valsalva aneurysm (SOVA) is a rare clinical entity. Clinical manifestations can vary from an incidental finding on an imaging study to a life-threatening emergency. We report a case of a 51-year-old female with a large symptomatic left SOVA. Echocardiogram and computed tomography angiography (CTA) of the chest revealed marked dilatation of the left sinus of Valsalva, measuring 7.5 cm. This resulted in superior displacement of the left main coronary artery. Surgical repair of the aneurysm with reimplantation of the right and left coronary arteries was performed in addition to aortic valve replacement (Bentall procedure). The patient had an uneventful postoperative course and remains asymptomatic at the three-month follow-up visit.
International Journal of Cardiology | 2017
Mohsin Salih; Aiman Smer; Richard Charnigo; Mohamed Ayan; Yousef Darrat; Mahmoud Traina; Gustavo Morales; Luigi DiBiase; Andrea Natale; Claude S. Elayi
American Journal of Cardiology | 2017
Aiman Smer; Alok Saurav; Muhammad Soubhi Azzouz; Mohsin Salih; Mohamed Ayan; Ahmed Abuzaid; Abhilash Akinapelli; Arun Kanmanthareddy; Lynda E. Rosenfeld; Faisal M. Merchant; Hussam Abuissa
Case Reports in Medicine | 2015
Mohsin Salih; Tarake Aljarod; Mohamed Ayan; Melnick Jeffrey; Bobby H. Shah
Journal of the American College of Cardiology | 2018
Mohsin Salih; Mohamed Ayan; Gbolahan Ogunbayo; Adnan Elghezewi; Maya Guglin