Mrinalini Sachin Oza | Researchain

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Featured researches published by Mrinalini Sachin Oza.

Bioorganic & Medicinal Chemistry Letters | 2012

Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway

Ian Bruce; Mohammed Akhlaq; Graham Charles Bloomfield; Emma Budd; Brian Cox; Bernard Cuenoud; Peter Finan; Peter Gedeck; Julia Hatto; Judy Hayler; Denise Head; Thomas H. Keller; Louise Kirman; Catherine Leblanc; Darren Le Grand; Clive Mccarthy; Desmond O’Connor; Charles Owen; Mrinalini Sachin Oza; Gaynor Elizabeth Pilgrim; Nicola Press; Lilya Sviridenko; Lewis Whitehead

Using a parallel synthesis approach to target a non-conserved region of the PI3K catalytic domain a pan-PI3K inhibitor 1 was elaborated to provide alpha, delta and gamma isoform selective Class I PI3K inhibitors 21, 24, 26 and 27. The compounds had good cellular activity and were selective against protein kinases and other members of the PI3K superfamily including mTOR and DNA-PK.

Archive | 2003

5-phenylthiazole derivatives and use as pi3 kinase inhibitors

Ian Bruce; Peter Finan; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Press; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza; Lena Shukla

Archive | 2004

5-Phenylthiazole derivatives and their use as p13 kinase inhibitors

Graham Charles Bloomfield; Ian Bruce; Catherine Leblanc; Mrinalini Sachin Oza; Lewis Whithead; Bernard Cuenoud; Thomas H. Keller; Louise Kirman; Clive Mccarthy; Gaynor Elizabeth Woodward

Archive | 2009

5-phenylthiazole derivative, and use as pi3 kinase inhibitor

Graham Charles Bloomfield; Ian Bruce; Peter Finan; Judy Hayler; Louise Kirman; Catherine Leblanc; Clive Mccarthy; Mrinalini Sachin Oza; Nicola Press; Lena Shukla; Lewis Whitehead; イアン・ブルース; カトリーヌ・ルブラン; クライブ・マッカーシー; グレアム・チャールズ・ブルームフィールド; ジュディ・ヘイラー; ニコラ・プレス; ピーター・フィナン; ムリナリニ・サチン・オザ; ルイーズ・カーマン; ルイス・ホワイトヘッド; レナ・シュクラ

Archive | 2004

5-phenylthiazolderivate und deren verwendung als p13-kinase-inhibitoren 5-phenylthiazolderivate and their use as p13 kinase inhibitors

Graham Charles Bloomfield; Ian Bruce; Catherine Leblanc; Mrinalini Sachin Oza; Lewis Whitehead

Archive | 2004

5-phenylthiazolderivate and their use as p13 kinase inhibitors

Graham Charles Bloomfield; Ian Bruce; Catherine Leblanc; Mrinalini Sachin Oza; Lewis Whitehead

Archive | 2003

Derives du 5-phenylthiazol et leurs utilisations comme inhibiteurs de la pi3 kinase

Ian Bruce; Peter Finan; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Elaine Blair; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza

Archive | 2003

A combination of a 5-phenylthiazolforbindelse as PI3 kinase inhibitor with an anti-inflammatory, bronchodilatory or antihistamine drug

Ian Bruce; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Press; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza; Lena Shukla; Peter Finan

Archive | 2003

Combination of a 5-phenylthiazole compound as PI3 kinase inhibitor with an antiinflammatory, bronchodilatory or antihistamine drug

Ian Bruce; Peter Finan; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Press; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza; Lena Shukla

Archive | 2003

Kombination aus einem 5-phenylthiazolderivat als PI3-Kinasehemmer und eine entzündungshemmender, bronchodilatatorische oder antihistaminischen Verbindung

Ian Bruce; Peter Finan; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Press; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza; Lena Shukla

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