Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Nicola Press is active.

Publication


Featured researches published by Nicola Press.


Bioorganic & Medicinal Chemistry Letters | 2012

Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway

Ian Bruce; Mohammed Akhlaq; Graham Charles Bloomfield; Emma Budd; Brian Cox; Bernard Cuenoud; Peter Finan; Peter Gedeck; Julia Hatto; Judy Hayler; Denise Head; Thomas H. Keller; Louise Kirman; Catherine Leblanc; Darren Le Grand; Clive Mccarthy; Desmond O’Connor; Charles Owen; Mrinalini Sachin Oza; Gaynor Elizabeth Pilgrim; Nicola Press; Lilya Sviridenko; Lewis Whitehead

Using a parallel synthesis approach to target a non-conserved region of the PI3K catalytic domain a pan-PI3K inhibitor 1 was elaborated to provide alpha, delta and gamma isoform selective Class I PI3K inhibitors 21, 24, 26 and 27. The compounds had good cellular activity and were selective against protein kinases and other members of the PI3K superfamily including mTOR and DNA-PK.


Archive | 2004

Inhibitors of phosphatidylinositol 3-kinase

Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd


Archive | 2003

5-phenylthiazole derivatives and use as pi3 kinase inhibitors

Ian Bruce; Peter Finan; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Press; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza; Lena Shukla


Bioorganic & Medicinal Chemistry Letters | 2005

A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential

Neil John Press; Roger John Taylor; Joseph D. Fullerton; Pamela Tranter; Clive Mccarthy; Thomas H. Keller; Lyndon Nigel Brown; Robert Cheung; Julie Christie; Sandra Haberthuer; Julia Hatto; Mark Keenan; Mark Mercer; Nicola Press; Helene Sahri; Andrew R. Tuffnell; Morris Tweed; John R. Fozard


Archive | 2009

5-phenylthiazole derivative, and use as pi3 kinase inhibitor

Graham Charles Bloomfield; Ian Bruce; Peter Finan; Judy Hayler; Louise Kirman; Catherine Leblanc; Clive Mccarthy; Mrinalini Sachin Oza; Nicola Press; Lena Shukla; Lewis Whitehead; イアン・ブルース; カトリーヌ・ルブラン; クライブ・マッカーシー; グレアム・チャールズ・ブルームフィールド; ジュディ・ヘイラー; ニコラ・プレス; ピーター・フィナン; ムリナリニ・サチン・オザ; ルイーズ・カーマン; ルイス・ホワイトヘッド; レナ・シュクラ


Archive | 2004

Derives de thiazole utilises comme inhibiteurs de la phosphatidylinositol-3-kinase

Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd


Archive | 2004

Thiazole derivatives as inhibitors of phosphatidylinositol 3-kinase

Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd


Archive | 2004

Inhibiteurs de phosphatidylinositol 3-kinase

Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd


Archive | 2004

Phosphatidylinositol 3-kinase inhibitoren

Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd


Archive | 2004

Inhibitors phosphatidylinositol 3-kinase.

Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd

Collaboration


Dive into the Nicola Press's collaboration.

Researchain Logo
Decentralizing Knowledge