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Featured researches published by Nicola Press.
Bioorganic & Medicinal Chemistry Letters | 2012
Ian Bruce; Mohammed Akhlaq; Graham Charles Bloomfield; Emma Budd; Brian Cox; Bernard Cuenoud; Peter Finan; Peter Gedeck; Julia Hatto; Judy Hayler; Denise Head; Thomas H. Keller; Louise Kirman; Catherine Leblanc; Darren Le Grand; Clive Mccarthy; Desmond O’Connor; Charles Owen; Mrinalini Sachin Oza; Gaynor Elizabeth Pilgrim; Nicola Press; Lilya Sviridenko; Lewis Whitehead
Using a parallel synthesis approach to target a non-conserved region of the PI3K catalytic domain a pan-PI3K inhibitor 1 was elaborated to provide alpha, delta and gamma isoform selective Class I PI3K inhibitors 21, 24, 26 and 27. The compounds had good cellular activity and were selective against protein kinases and other members of the PI3K superfamily including mTOR and DNA-PK.
Archive | 2004
Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd
Archive | 2003
Ian Bruce; Peter Finan; Catherine Leblanc; Clive Mccarthy; Lewis Whitehead; Nicola Press; Graham Charles Bloomfield; Judy Hayler; Louise Kirman; Mrinalini Sachin Oza; Lena Shukla
Bioorganic & Medicinal Chemistry Letters | 2005
Neil John Press; Roger John Taylor; Joseph D. Fullerton; Pamela Tranter; Clive Mccarthy; Thomas H. Keller; Lyndon Nigel Brown; Robert Cheung; Julie Christie; Sandra Haberthuer; Julia Hatto; Mark Keenan; Mark Mercer; Nicola Press; Helene Sahri; Andrew R. Tuffnell; Morris Tweed; John R. Fozard
Archive | 2009
Graham Charles Bloomfield; Ian Bruce; Peter Finan; Judy Hayler; Louise Kirman; Catherine Leblanc; Clive Mccarthy; Mrinalini Sachin Oza; Nicola Press; Lena Shukla; Lewis Whitehead; イアン・ブルース; カトリーヌ・ルブラン; クライブ・マッカーシー; グレアム・チャールズ・ブルームフィールド; ジュディ・ヘイラー; ニコラ・プレス; ピーター・フィナン; ムリナリニ・サチン・オザ; ルイーズ・カーマン; ルイス・ホワイトヘッド; レナ・シュクラ
Archive | 2004
Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd
Archive | 2004
Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd
Archive | 2004
Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd
Archive | 2004
Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd
Archive | 2004
Ian Bruce; Bernard Cuenoud; Thomas H. Keller; Gaynor Elizabeth Pilgrim; Nicola Press; Grand Darren Mark Le; Cathy Ritchie; Barbara Valade; Judy Hayler; Emma Budd