Munar Lubis

Contribution of Plasmodium knowlesi to multi-species human malaria infections in North Sumatera, Indonesia

Summary Indonesia is aiming for malaria elimination by 2030. A parasitological survey of 3731 individuals in North Sumatera province used polymerase chain reaction to identify 1169 with parasitemia and highly specific amplification of sicavar genes to identify Plasmodium knowlesi infection in 377.

Relationship between Enuresis and Childrenrs Quality of Life

Enuresis had been reported affecting children in many aspects of life such as physosocial, emotion and school performance which leads to Quality of Life (QoL) impairment. This study aims to assess the relationship between enuresis and children’s quality of life. A cross-sectional study was performed in children between the age 5 to 18 years at Muara Batang Gadis, North Sumatera in April 2016. Enuresis was examined using questionnaire International Association for Child and Adolescent Psychiatry and Allied Professions (IACAPAP) and the measurement quality of life using Pediatric Quality of Life Inventory (PedsQL) Generic Core Scales 4.0 version. Data was considered significant if p < 0.05. There was a significant difference in emotion segment of QoL in 13-18 yo enuretic children compared to healthy children and significant differences in PedsQL total score and emotion segment by age group in enuresis children. Keywords—Enuresis, quality of life, children

Abstract P-296: INCREASED URINARY ALBUMIN-CREATININE RATIO IN SEPTIC CHILDREN ADMITTED TO PEDIATRIC INTENSIVE CARE UNIT

Twenty-one pediatric patients (from 1.0 year to 15.5 years) were recruited and 69 treatments were recorded. The basic CI was 3.4 (2.4, 6.1) L/min/m2, basic SVI was 43 (26, 75) ml/m2/beat. During the beginning of therapy, mean arterial pressure, CI and SVI all dropped from the baseline (P=0.000), whereas heart rate increased. During the course of CRRT, CI and SVI kept on dropping and stayed at a relatively lower level. Course CI was 3.0 (2.4, 4.6) L/min/m2 and course SVI was 28 (21, 57) ml/m2/beat. At the end of therapy, CI was 3.4 (2.5, 5.3) L/min/ m2, with no significant difference from the baseline (P=0.073). However, the SVI at the end of therapy was 35 (25, 67) ml/m2/beat, higher than the course SVI but still lower than the basic SVI, the differences were statistically significant (P<0.05).

Abstract P-200: THE ASSOCIATION BETWEEN THE LEVEL OF ANTITHROMBIN III AND PELOD SCORE WITH MORTALITY IN CHILDREN WITH SEPSIS IN PEDIATRIC INTENSIVE CARE UNIT

From the 41 children, the low antithrombin III was found in 13 children (31.7%). From all the death case, we found antithrombin III level is low in 8 of 13 children (61.5%) (p=0.184; PR = 1.57, 95% Cl 0.83 to 2.94). From 22 children with high PELOD score, 18 was died (p=<0.001; PR = 1.57, 95% Cl 2.28–105.81). Of the 10 children with low level antithrombin III and high PELOD score, there were 8 children died (p=0.026; PR = 2.26, 95% Cl 1.28–3.97).

Habitual snoring and primary enuresis in children

Background Obstructive sleep-disordered breathing is assumed to be associated with primary enuresis in children. Prolonged enuresis may cause developmental and emotional disorders, as well as poor school performance. Objective To determine the relationship between habitual snoring and primary enuresis in children. Methods A cross-sectional study was conducted in Muara Batang Gadis District, North Sumatera in April 2016. Subjects were children aged 5-14 years. The Sleep Disturbance Scale for Children (SDSC) Questionnaire was used to measure the symptoms of sleep disordered breathing; the International Association Child and Adolescent Psychiatry and Allied Professions (IACAPAP) Questionnaire was used to assess for the presence of primary enuresis. The questionnaires were answered by the children’s parents. Data were analyzed using Chi-square and logistic regression tests. A P value of <0.05 was considered to be statistically significant. Results The mean age of 110 participants was 9.23 (SD 2.16) years. Twenty-seven (24.5%) subjects snored more than three nights per week (habitual snorers) and 18 (16.4%) subjects had primary enuresis. There was a significantly higher percentage of habitual snorers with enuresis than that of snorers without enuresis (55.5% vs. 18.4%, respectively) (P<0.05). Conclusion There is a significant relationship between habitual snoring and primary enuresis. [Paediatr Indones. 2018;58:11622; doi: http://dx.doi.org/10.14238/pi58.3.2018.116-22].

Mean Blood Pressure Difference among Adolescents Based on Dyssomnia Types

BACKGROUND: Dyssomnia is the most frequent sleep disturbance and associated with increased blood pressure. There has been no study determining the difference in mean blood pressure based on dyssomnia types among adolescents. OBJECTIVE: To determine the difference in mean blood pressure among adolescents based on dyssomnia types. METHODS: Cross-sectional study was conducted in SMP Negeri 1 Muara Batang Gadis in April 2016. Samples were students having sleep disturbance based on Sleep Disturbance Scale for Children (SDSC) questionnaire. Stature and blood pressure data were collected along with demographic data and sleep disorder questionnaire. Analyses were done with Kruskal-Wallis test and logistic regression. P - value < 0.05 was considered significant. RESULTS: Seventy-six samples were obtained with mean age 13.9 (SD 1.14) years - old. Dyssomnia proportion and hypertension were 72/76 and 20/76 respectively. Mean systolic (SBP) and diastolic blood pressure (DBP) was 111.1 (SD 16.46) mmHg and 70.3 (SD 11.98) mmHg respectively. Mean SDSC score was 49.7 (SD 8.96), and the most frequent dyssomnia type was disorders of initiating and maintaining sleep. Age and sex were not the risk factors of hypertension in dyssomnia. There was a significant difference in mean SBP (P = 0.006) and DBP (P = 0.022) based on dyssomnia types. Combination dyssomnia type had the highest mean blood pressure among dyssomnia types. CONCLUSION: There is a significant difference in mean blood pressure among adolescents based on dyssomnia types.

Hemolytic anemia in falciparum and vivax malarial patients based on serum bilirubin examination

Objective To examine hemolysis in falciparum and vivax malarial patients based on serum bilirubin examination. Methods A cross sectional study was conducted on children younger than 15 years of age who visited public health center in the district of Mandailing Natal with complaints of fever, shivering, pale, jaundice, diarrhea, or headache between April 9 th and April 19 th 2001. Variables recorded were age, gender, body weight, body height, symptoms and signs, anti malarial drugs, and laboratory test results. Thin and thick blood smears were done as diagnostic tools of malaria. Thin blood smear was also performed to deter- mine the level of malaria parasites in blood (parasitemia) and to examine the morphology of red blood cells. Hemolysis was deter- mined by bilirubin examination. Results In P. falciparum malaria, there was a moderate correlation (r=0.68, p<0.0001) between parasitemia and indirect bilirubin con- centration. While in P. vivax malaria, there was only a weak corre- lation (r=0.46, p=0.007) between parasitemia and indirect bilirubin concentration. It was also found that in falciparum malaria, para- sitemia, total and indirect bilirubin concentrations were significantly higher than that in vivax malaria, with p values of 0.009, 0.015 and 0.003, respectively. Conclusion Hemolysis in falciparum malaria is more severe than that in P. vivax malaria, with marked elevation of indirect bilirubin. The elevation of serum bilirubin correlated with parasitemia

Parental knowledge, attitude and practice on malaria in Mandailing Natal district

Background Malaria is still considered to be an important health problem in Indonesia. Malaria has been found in islands with different degree of endemicity. Behavior of the community is one of the factors affecting the incidence of malaria in Mandailing Natal district. Objective To know the parental knowledge, attitude, and practice among parents whose children suffered from malaria or not. Methods A cross sectional study was conducted in six primary schools and one health centre in October 2004. Subjects were parents whose children were malaria positive and malaria negative based on laboratory examination. Sample size was 85 parents for each group. Selected respondents were interviewed using structured questionnaire. Degree of knowledge, attitude, and practice on malaria were established using scoring system within three categories: good, less, and poor. Data were collected and presented using chi-square and P<0.05 was considered as a level of significant. Results The mean age of 85 parents whose children were positive malaria, was 38.47 years (SD 6.67) and the mean age of those whose children were negative malaria was 40.41 years (SD 8.05). Parent’s education level was 62.9% primary school and 90% of their children were school-aged. There were significant differences on parental knowledge, attitude and practice in each group (P<0.05). There was also a significant correlation between occupation and knowledge, but not between parental education level and parental age. Parental knowledge and attitude on the incidence of malaria in Mandailing Natal district were good, though their practice were poor. Conclusion There are significant differences on parental knowledge, attitude and practice, between parents whose children were positive and negative for malaria.