Murat Akkocaoglu

Implant stability and bone density: assessment of correlation in fresh cadavers using conventional and osteotome implant sockets

OBJECTIVE To compare the primary stability of implants placed in conventional and osteotome sites and to evaluate the level of correlation between cutting torque measurements, resonance frequency analysis (RFA), and bone density. MATERIALS AND METHODS Eight human femoral heads were scanned with computed tomography for bone density measurements as Hounsfield units (HU), and individualized computed tomography-based surgical stents were prepared for placement of implants. Five implant sockets were prepared in each collum (CoF), caput (CaF), and trochanter (Tr-MM) section of the femoral heads using the conventional drilling technique or by a combination of drilling and use of an osteotome. Cutting-torque values (CTV) of the implants were measured by a manual torque wrench, followed by determination of implant stability quotients (ISQ) by RFA. RESULTS The CTVs of implants were similar in the conventional group, but different in the osteotome group (P<0.05). There was a general tendency toward achieving higher CTV and ISQ values in CoF than CaF and Tr-MM (P<0.05), and measurements in CaF and Tr-MM were comparable (P>0.05). The mean HU of sites were similar, although CoF had higher HU values (P>0.05). CTV of implants in CaF and Tr-MM and ISQ values in CoF in the conventional groups were higher than those in the osteotome groups (P<0.05). The correlation between CTV and HU in Tr-MM was significant in the osteotome group, although no other correlations between CTV, ISQ, and HU could be detected (P>0.025). CONCLUSIONS Conventional placement led to higher implant stability than the drilling and osteotome technique used in the study. No correlation could be found between CTV, RFA, and bone density.

Torque-fitting and resonance frequency analyses of implants in conventional sockets versus controlled bone defects in vitro

The primary stability of implants should be high on insertion into fresh extraction sockets. Torque-fitting and resonance frequency analyses (RFA) are used to assess primary implant anchorage and stability. The torque-fitting and RFA of implants placed in conventional surgical sockets and sockets with controlled coronal bone defects was compared. The possible relation between torque-fitting and RFA was explored. Ø 3.3 mm x 12 mm implants were placed in 16 sockets finalized with Ø 2.8mm surgical pilot drills in the right iliac crests of two fresh cadavers (control). In the test group, implants were placed into sockets prepared by Ø 2.8mm drill followed by Ø 4.2mm twist drills to a depth of 6mm to create circumferential controlled coronal bone defects (50% bone loss). Primary implant stability was assessed using insertion torque values (ITV) followed by RFA. Mean ITV and RFA measurements for test groups (7.83+/-0.91 N cm and 40.88+/-3.57) were significantly lower than controls (14.80+/-1 N cm and 66.31+/-0.9) (P<0.05). Reductions of ITV and RFA measurements in relation to bone defect were 47% and 38%. The existence of controlled bone defects eliminating contact coronally leads to decrease in torque-fitting and primary stability of implants. No relationship was observed between torque-fitting and RFA.

Fresh-frozen vs. embalmed bone: is it possible to use formalin-fixed human bone for biomechanical experiments on implants?

PURPOSE As formalin is an extremely reactive electrophilic chemical that reacts with tissues, the purpose of this study was to explore whether formalin fixation could potentially alter the mechanical properties of bone tissue and have an effect on the primary stability measurements of implants. MATERIAL AND METHODS Ø 3.3 x 8 mm, Ø 4.1 x 8 mm, and Ø 4.8 x 8 mm implants were placed on sockets prepared into the anterior surface of the radius of two fresh-frozen human cadavers. The insertion torque of each implant was quantified using a strain-gauged torque-wrench connected to a data acquisition system at a sample rate of 10 KHz, and resonance frequency analysis measurements were also undertaken for each implant. The cadavers were then subjected to embalment with 10% formalin for 3 months, and the same experiments were undertaken on the contra lateral radius of the cadavers. RESULTS The insertion torques before and after chemical fixation were similar for Ø 3.3 mm (P>0.05), and higher values were obtained for Ø 4.1 mm and Ø 4.8 mm implants after chemical fixation (P<0.05). The resonance frequency analysis values before and after chemical fixation were similar for all implants (P>0.05). CONCLUSIONS Implants have higher insertion torque values in formalin-fixed bone than fresh-frozen human bone, but similar implant stability quotients in both cases. The insertion torque technique can detect the difference between formalin-fixed and fresh-frozen human bone, but resonance frequency analysis cannot.

Numerical simulation of in vivo intraosseous torsional failure of a hollow-screw oral implant

BackgroundOwing to the complexity and magnitude of functional forces transferred to the bone-implant interface, the mechanical strength of the interface is of great importance. The purpose of this study was to determine the intraosseous torsional shear strength of an osseointegrated oral implant using 3-D finite element (FE) stress analysis implemented by in vivo failure torque data of an implant.MethodsA Ø 3.5 mm × 12 mm ITI® hollow screw dental implant in a patient was subjected to torque failure test using a custom-made strain-gauged manual torque wrench connected to a data acquisition system. The 3-D FE model of the implant and peri-implant circumstances was constructed. The in vivo strain data was converted to torque units (N.cm) to involve in loading definition of FE analysis. Upon processing of the FE analysis, the shear stress of peri-implant bone was evaluated to assume torsional shear stress strength of the bone-implant interface.ResultsThe in vivo torque failure test yielded 5952 μstrains at custom-made manual torque wrench level and conversion of the strain data resulted in 750 N.cm. FE revealed that highest shear stress value in the trabecular bone, 121 MPa, was located at the first intimate contact with implant. Trabecular bone in contact with external surface of hollow implant body participated shear stress distribution, but not the bone resting inside of the hollow.ConclusionThe torsional strength of hollow-screw implants is basically provided by the marginal bone and the hollow part has negligible effect on interfacial shear strength.

Human ex vivo bone tissue strains around immediately-loaded implants supporting mandibular fixed prostheses.

Purpose:The purpose of this study was to qualify and quantify bone strains around immediately-loaded implants supporting mandibular fixed prostheses with regard to number of implant support. Materials:Linear strain gauges were bonded on the labial bone of 5 Straumann dental implants placed in the mandibular symphysis region of 2 completely edentulous mandibles of fresh human cadavers. Installation torque value of each implant was measured by a custom-made torque wrench and resonance frequency analyses were undertaken. A one-piece full-arch fixed prosthesis was fabricated for each cadaver and 2 miniature load cells were integrated in the cantilever region of the prostheses for controlled loading experiments. 5-, 4-, and 3-implant support designs were consecutively tested. Strain measurements were performed at a sample rate of 10 KHz and under a maximum load of 100 N, simultaneously monitored from a computer connected to data acquisition system. Results:The installation torque values and implant stability quotient values of the implants ranged between 42.12 to 145.67 N cm and 61 to 80, respectively. Between-group comparisons revealed that the highest strain magnitudes were recorded for the 3-implant design followed by the 4- and 5-implant designs, although there was a tendency toward similar load partitioning between 4- and 5-implant designs (P < 0.05). Conclusions:Bone strains around 3-implant supported mandibular fixed prostheses is significantly higher than those around 4- and 5-implant designs, and this may lead to failure of supporting implants. Four- and 5-implant designs might have similar clinical outcome.

Comparison between peri-implant bone level changes of implants placed during and 3 months after iliac bone grafting

OBJECTIVE The aim of this study was to compare the peri-implant bone level changes of implants placed during and 3 months after bone grafting from the iliac crest. STUDY DESIGN A total of 103 implants were placed: 42 during the grafting and 61 at 3 months after the grafting procedure. All patients were grafted with iliac bone from the anterosuperior iliac crest. Bone resorption was evaluated with cone beam computed tomography in all patients at their last control visit. Periodontal health was assessed via the gingival and plaque indices and pocket depths around the dental implants. RESULTS Mean bone resorption values at the buccal, lingual, mesial, and distal sides of the implants were 1.08 mm, 0.36 mm, 0.30 mm, and 0.25 mm, respectively, in the delayed group, and 1.87 mm, 1.25 mm, 0.92 mm, and 1.23 mm, respectively, in the simultaneous group; the differences between the groups were significant. There were no significant between-group differences in the gingival or plaque indices or pocket depths. The mean follow-up period was 29 months. CONCLUSIONS For reconstructing atrophic jaws, bone grafting from the iliac crest and implant placement after 3 months is a reliable technique with a high success rate and less bone resorption.