Mustafa Uçar

Relation of Neutrophil-to-Lymphocyte Ratio With GRACE Risk Score to In-Hospital Cardiac Events in Patients With ST-Segment Elevated Myocardial Infarction

In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P < .001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P < .001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r = .803, P < .001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.

Type 1 neurofibromatosis complicated by pulmonary arterial hypertension: a case report

Neurofibromatosis type I (NF1) is a rare genetic disease caused by mutations in the NF1 gene, which encodes the tumor suppressor neurofibromin. Precapillary pulmonary hypertension is a severe complication of NF1, initially described in patients with advanced parenchymal lung disease, which may complicate the course of NF1. Presently described is a case of neurofibromatosis complicated by pulmonary hypertension.

Early thrombus formation in patient with HeartWare left ventricular assist device presenting with acute heart failure.

Heart failure is one of the leading causes of mortality and morbidity in the world. Heart transplantation is still the gold standard therapy despite emerging treatment options. Due to the limited number of available donors, the use of ventricular assist devices has increased. However, increasing incidences of complications are observed with using these devices. In this article, surgical treatment of a huge mobile thrombus formation in an inflow cannula due to ineffective anticoagulation in a 59 year-old man who received a HeartWare ventricular assist device because of ischemic cardiomyopathy is presented.

Complete AV block and cardiac syncope in a patient with Duchenne muscular dystrophy

Duchenne muscular dystrophy is an X linked hereditary progressive neuromuscular disease and it is characterized by development of weakness and atrophy in affected muscles. In late phases of disease with involvement of respiratory and cardiac muscles, patients die because of respiratory and cardiac failure. Cardiomyopathy is a common complication and various types of arrhythmia because of conduction system involvement can be seen. Herein we present a case with Duchenne muscular dsytrophy who was admitted to our clinic at an older age because of complete atrioventricular block without cardiomyopathy.

Pulmonary Endarterectomy For Large Vessel Pulmonary Arteritis Mimicking Chronic Thromboembolic Disease

Takayasus arteritis is a chronic, non-specific primary and inflammatory disease of large vessels, especially the aorta and its branches. Although pulmonary artery involvement is common, clinical signs of pulmonary artery involvement as the initial presentation is rare. Considering Takayasus arteritis in the early diagnosis is important. In this article, we report a 23-year-old female patient of Takayasus arteritis who was treated with successful surgery combined with medical therapy.

Left ventricular lateral wall pseudoaneurysm presented with decompensated heart failure.

A 54-year-old woman was admitted to the emergency department with chest pain and orthopnoea for the last 1 month. She had hypertension and type 2 diabetes mellitus. ECG showed ST segment elevation and pathological Q waves in leads I and aVL suggesting previous lateral myocardial infarction (MI). Physical examination revealed blood pressure of 90/60 mm Hg; bibasilar rales and a (2/6)° late systolic murmur along the left sternal edge due to papillary muscle dysfunction was noted. Antianginal, antithrombotic and …