Muzaffer Öztürk

High cholesterol diet supplemented with sunflower seed oil but not olive oil stimulates lipid peroxidation in plasma, liver, and aorta of rats

Abstract To determine the effect of a high cholesterol diet supplemented with sunflower seed oil or olive oil on plasma, liver, and aorta lipid peroxidation, rats were fed a basal diet, a high cholesterol diet (basal diet containing 2% cholesterol and 0.5% cholic acid), or a high cholesterol diet supplemented with 10% ( wt wt ) sunflower seed oil or 10% ( wt wt ) olive oil for 4 months. In rats fed the high cholesterol diet supplemented with sunflower seed oil, plasma, liver, and aorta lipid peroxide levels and the aorta cholesterol to phospholipid ratio were greater than in rats fed the high cholesterol diet. In contrast, no change was observed in plasma, liver, and aorta lipid peroxidation and the cholesterol to phospholipid ratio in rats fed the high cholesterol diet containing olive oil as compared with the high cholesterol diet. In addition, atherosclerotic lesions were not detected in the aorta of all groups. We concluded that a high cholesterol diet supplemented with polyunsaturated fats, but not with monounsaturated fats, seems to have a tendency to exaggerate lipid peroxidation.

Long-Term Prognosis after a First Myocardial Infarction in Turkey: Determinants of Mortality and Reinfarction

Long-term prognosis of a first myocardial infarction and factors associated with late cardiac mortality and reinfarction were studied in 718 survivors. Patients have been followed up for 1-10 years (mean 57.6 +/- 39.6 months). None of the patients underwent coronary bypass surgery in the follow-up period. Cumulative mortality rates were 8.6% in the first year, 17.9% in 3 years, 26.4% in 5 years and 36.5% in 10 years. The type and site of myocardial infarction (Q-wave versus non-Q-wave and anterior versus infero-posterior) were found to have no independent prognostic importance. The cardiac mortality was best predicted by the occurrence of congestive heart failure in the coronary care unit. Other determinants of late outcome were the presence of ventricular arrhythmias, left bundle branch block, and the occurrence of stable or unstable angina pectoris or reinfarction during the follow-up period. Usage of antiplatelet or anticoagulant drugs was not found to affect mortality. Reinfarction rates were 4, 9.9, 15.5 and 28% in 1, 3, 5 and 10 years, respectively, and no relation was found between the type and location of myocardial infarction and reinfarction rate. Reinfarction was higher in patients receiving anticoagulants and in patients with postmyocardial infarction angina. Our findings suggest that the prognosis of patients with a first acute myocardial infarction in Turkey is not different from that in Western populations and factors influencing prognosis are similar to those previously reported.

Electrophysiologic Characteristics of Wide QRS Complexes during Pharmacologic Termination of Sustained Supraventricular Tachycardias with Verapamil and Adenosine: Observations from Electrophysiologic Study

Background: In this study we evaluate wide QRS complexes observed during pharmacologic termination of supraventricular tachycardias.

Asymptomatic Pericardial Hydatid Cyst.

Cardiac involvement is rare in hydatid disease, but it carries a significant risk of potentially lethal complications. Cardiac hydatid cysts are mostly intramyocardial. Pericardial hydatid cysts without myocardial involvement are much less frequent. Cardiac imaging techniques, particularly two-dimensional echocardiography, are more useful in the detection of cardiac cysts. We present an incidentally detected, asymptomatic, pericardial hydatid cyst.

Ein chronisches Koronarpseudoaneurysma nach Stentimplantation

Um die Rate akuter und subakuter Stentthrombosen zu vermindern, werden Stents nach der neuen Technik mit hohem Druck und/oder mit Enddilatation durch größere Ballons in Koronarstenosen implantiert. In dieser Arbeit wird über ein chronisches Koronarpseudoaneurysma berichtet, das nach einer erfolgreichen Stentimplantation im Ramus interventricularis anterior wahrscheinlich wegen Enddilatation mit sehr hohem Druck aufgetreten ist. Recently, as a part of new stent implantation strategy in order to decrease stent thrombosis, final dilatations with high pressure and/or higher sized balloons were applied after the initial deployment of the stent. In this paper, we presented a case of chronic coronary pseudoaneurysm which occured after an initially successful stent implantation in the left anterior descending artery, probably due to high pressure final dilatation.