Nancy-Ellen Haynes
Hoffmann-La Roche
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Publication
Featured researches published by Nancy-Ellen Haynes.
Bioorganic & Medicinal Chemistry Letters | 2014
Paul Gillespie; Sherrie Lynn Pietranico-Cole; Michael Paul Myers; Joseph Anthony Bilotta; Karin Conde-Knape; Nader Fotouhi; Robert A. Goodnow; Kevin Richard Guertin; Matthew Michael Hamilton; Nancy-Ellen Haynes; Baolian Liu; Lida Qi; Yonglin Ren; Nathan Robert Scott; Sung-Sau So; Cheryl Spence; Rebecca Taub; Kshitij Chhabilbhai Thakkar; Jefferson Wright Tilley; Catherine Zwingelstein
Starting from screening hit, (4S,7R)-1,7,8,8-tetramethyl-2-phenyl-1,2,4,5,6,7-hexahydro-4,7-methano-indazol-3-one (7), we optimized the potency and pharmacokinetic properties. This led to the identification of compounds with good in vivo activity in a mouse pharmacodynamic model of inhibition of 11βHSD1.
Archive | 2003
Shaoqing Chen; Wendy Lea Corbett; Kevin Richard Guertin; Nancy-Ellen Haynes; Robert Francis Kester; Francis A. Mennona; Steven Gregory Mischke; Yimin Qian; Ramakanth Sarabu; Nathan Robert Scott; Kshitij Chhabilbhai Thakkar
Archive | 2001
Fred T. Bizzarro; Nancy-Ellen Haynes; Ramakanth Sarabu
Archive | 2007
Kevin William Anderson; Nader Fotouhi; Paul Gillespie; Robert Alan Goodnow; Kevin Richard Guertin; Nancy-Ellen Haynes; Michael Paul Myers; Sherrie Lynn Pietranico-Cole; Lida Qi; Pamela Loreen Rossman; Nathan Robert Scott; Kshitij Chhabilbhai Thakkar; Jefferson Wright Tilley; Qiang Zhang
Archive | 2006
Nancy-Ellen Haynes; Denis John Kertesz; Sherrie Lynn Pietranico-Cole; Yimin Qian; Nathan Robert Scott; Sung-Sau So; Kshitij Chhabilbhai Thakkar; Jefferson Wright Tilley
Archive | 2007
Kevin William Anderson; Nader Fotouhi; Paul Gillespie; Robert Alan Goodnow; Kevin Richard Guertin; Nancy-Ellen Haynes; Michael Paul Myers; Sherrie Lynn Pietranico-Cole; Lida Qi; Pamela Loreen Rossman; Nathan Robert Scott; Kshitij Chhabilbhai Thakkar; Jefferson Wright Tilley; Qiang Zhang
Archive | 2009
Steven Joseph Berthel; John A. Brinkman; Stuart Hayden; Nancy-Ellen Haynes; Robert Francis Kester; Lee Apostle Mcdermott; Yimin Qian; Ramakanth Sarabu; Nathan Robert Scott; Jefferson Wright Tilley
Archive | 2006
Wendy Lea Corbett; Joseph Grimsby; Nancy-Ellen Haynes; Robert Francis Kester; Paige E. Mahaney; Jagdish Kumar Racha; Ramakanth Sarabu; Ka Wang
Archive | 2006
Bruce L. Banner; Joseph Anthony Bilotta; Nader Fotouhi; Paul Gillespie; Jr. Robert Alan Goodnow; Matthew Michael Hamilton; Nancy-Ellen Haynes; Agnieszka Kowalczyk; Alexander V. Mayweg; Michael Paul Myers; Sherrie Lynn Pietranico-Cole; Nathan Robert Scott; Kshitij Chhabilbhai Thakkar; Jefferson Wright Tilley; Kevin Richard Guertin
Archive | 2008
Nancy-Ellen Haynes; Nathan Robert Scott; Jefferson Wright Tilley
