Nara Rejane Cruz de Oliveira

Investigação da ansiedade, depressão e qualidade de vida em pacientes portadores de osteoartrite no joelho: um estudo comparativo

INTRODUCTION Osteoarthritis (OA) affects the articular cartilage and subchondral bone, compromising the joint as a whole. The knee joint is characterized as one of the main sites of involvement of OA and the most significant risk factors for developing the disease are aging, overweight and female gender. OA is considered one of the most frequent causes of disability, which may affect the quality of life of the patients, favoring the onset of mental disorders. OBJECTIVE To investigate whether anxiety and depression symptoms are more significant in women with OA, when compared with women without this diagnosis, and to what extent this rheumatic disease affects the quality of life of these patients. METHODS The study included 75 women, mean age 67 years; 40 were diagnosed with knee OA and 35 without this diagnosis. The following instruments were used: State-Trait Anxiety Inventory (STAI), Beck Depression Inventory (BDI) and SF-36, a quality of life questionnaire. RESULTS Women with knee OA have higher rates of depression and anxiety when compared to controls; in addition, they have a lower quality of life. CONCLUSION We believe that the treatment of patients with OA should consider the combination of pharmacotherapy, psychotherapy, counseling and family support, in order to achieve a better quality of life.

Cytogenetic biomonitoring of oral mucosa cells of crack cocaine users

The aim of the present study was to comparatively evaluate genomic damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated oral mucosa cells from crack cocaine users by micronucleus test. A total of 30 crack cocaine users and 30 health controls (non-exposed individuals) were included in this setting. Individuals had epithelial cells from cheek mechanically exfoliated, placed in fixative, and dropped in clean slides, which were checked for the above nuclear phenotypes. The results pointed out significant statistical differences (p < 0.05) of micronucleated oral mucosa cells from crack cocaine users. Exposure to crack cocaine caused an increase of other nuclear alterations closely related to cytotoxicity such as karyolysis in oral cells as well. In summary, these data indicate that crack cocaine is able to induce chromosomal breakage and cellular death in oral mucosa cells of users.

Dependência de internet: manual e guia de avaliação e tratamento

”. Ao longo da obra, fundamentam a importância da inclusao da Dependencia de Internet como categoria nosologica dos transtornos mentais e apresentam propostas de avaliacao e tratamento. O livro possui quinze capitulos, divididos em duas partes. A primeira parte, intitulada “Compreendendo o comportamento do uso de internet e de-pendencia”, e composta por sete capitulos. O primeiro, “estimativas de prevalencia e modelos etiologicos de dependencia de internet”, descreve como diferentes modelos teoricos explicam o comportamento dependente, apontando a esquiva emocional e o papel da cultura na deter-minacao desse fenomeno. O segundo, “Avaliacao clinica de clientes dependentes de internet”, apresenta o processo de conceitualizacao e formas de avaliacao. O terceiro, “Interacao social na internet, bem-estar psicossocial e uso problematico da internet”, aborda as interacoes sociais virtuais associando as idiossincrasias do usuario. O quarto, “Usos e gratificacoes da dependencia de internet”, explica os padroes de uso problematico, suas propriedades reforcadoras e meca-nismos autorreguladores. O quinto e sexto capitulos, respectivamente, “Dependencia virtual de

The chemopreventive activity of apple against carcinogenesis: antioxidant activity and cell cycle control

Apples and their derivatives are rich in phytochemicals, including flavonoids (catechins, flavonols, quercetin) and phenolic acids (quercetin glycosides, catechin, epicatechin, procyanidins), vitamins, and fibers, that confer an important antioxidant property. Chemoprevention is defined by the use of natural or synthetic agents to interfere with the progression, reverse, or inhibit carcinogenesis, thereby reducing the risk of developing clinically invasive disease. The aim of this article is to present data generated from the use of apples as a chemopreventive agent in carcinogenesis using in-vivo and in-vitro test systems. Apple and its bioactive compounds can exert chemopreventive properties as a result of antioxidant activity and cell cycle control. However, future focus of research on apple such as identifying the specific phytochemical responsible for the anticarcinogenic effect, timing of consumption, and adequate amount of apples to achieve the best preventive effect using human large randomized-controlled trials is needed. Furthermore, animal studies are also relevant for better understanding the role of this fruit in human health as well as modulation of degenerative diseases such as cancer. Therefore, this area warrants further investigation as a new way of thinking, which would apply not only to apples but also to other fruit used as promising therapeutic agents against human diseases.

Saúde do estudante universitário: uma questão para reflexão

traz indicadores rele-vantes para a reflexao sobre esta populacao edemanda por novas reflexoes e pesquisas naarea. Historicamente elitizado, o ensino superi-or, especialmente o de natureza publica, tem semodificado consideravelmente nos ultimos anosvia politicas publicas de expansao, principal-mente no que se refere ao perfil dos estudan-tes

The BRICS Council for Exercise and Sport Science (BRICSCESS) - a new era has dawned

Highlights • BRICS is the acronym for an international association of 5 major emerging national economies: Brazil, Russia, India, China, and South Africa.• The BRICS Council of Exercise and Sports Science was founded to address the specific concerns of these countries in respect to the health and wellness of the people in BRICS countries.• One recognized overwhelming need is the development of future leaders/volunteers.• BRICSCESS in conjunction with the FLV program are in part assembled to foster the development and evolution of junior professionals in respect to the health and wellness of people.

Leisure practices in Brazil: a national survey on education, income, and social class

ABSTRACT This study is part of an extensive research project entitled “The Brazilian’s Leisure”. The aim of this paper is to identify in a broad manner how Brazilians’ use their leisure time based on their education, income and social class. The work was accomplished through empirical research and, whilst using broad reasoning procedures, comparisons were drawn between the representation of leisure and its actual activities. This paper specifically discusses the variables relating to education, income and social classes present from the data collected. It was identified that such variables have a distinct influence on the manner in which Brazilians spend their leisure time, and that it contributes to the rise of inequality when it comes to leisure.