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Tetrahedron Letters | 2000

An efficient synthesis of N-benzyl-3-sulfonyl glutarimides. Formal synthesis of the aromatase inhibitor AG-1

Meng‐Yang Chang; Bo-Rui Chang; Huo-Mu Tai; Nein-Chen Chang

Abstract A formal [3+3] cycloaddition strategy to substituted glutarimides was studied. N -Benzyl α-sulfonylacetamides and various α,β-unsaturated esters were used as starting materials.


Tetrahedron Letters | 2002

An efficient synthesis of γ-substituted α,β-unsaturated-δ-lactams. Formal synthesis of (±)-protoemetinol

Chang-Gin Huang; Bo-Rui Chang; Nein-Chen Chang

Abstract γ-Substituted α,β-unsaturated δ-lactams 1 was synthesized from α-sulfinyl acetamides 3 in three steps. Formal synthesis of (±)-protoemetinol was also reported.


Journal of Organic Chemistry | 1994

Bicyclo[3.2.1]octenones as building blocks in natural products synthesis. II: Formal synthesis of (±)-verbenalol

Chi-Peng Chang; Lung-Fu Hsu; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1999

Total Synthesis of (±)‐Boschnialactone and (±)‐Tetrahydroanhydrodesoxyaucubigenin

Meng‐Yang Chang; Ching‐Han Lin; An‐Yang Lee; Huo-Mu Tai; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1995

Formal Syntheses of (±)‐Verbenalol and (±)‐Udoteatrial

Huo-Mu Tai; Chau-Chen Yang; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1996

Bicyclo[3.2.1]octenones as Building Blocks in Natural Product Synthesis (V): Formal Synthesis of (±)-Specionin

† Meng-Yang Chang; Chi‐Peng Chang; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1994

Bicyclo[3.2.1]octenones As Building Blocks in Natural Products Synthesis (III). Total Synthesis of (±)-10-Deoxygeniposide Aglucone

Lung‐Fu Hsu; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1994

Bicyclo[3.2.1]octenones as Building Blocks in Natural Product Synthesis (IV): Formal Synthesis of (±)-Hydroxyloganin Aglucone

Chi‐Peng Chang; Wei‐Kung Yin; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1998

Alkoxide-Accelerated [1,3] Sigmatropic Shift of Bicyclo[3.2.1]oct-6-en-2-ols to 8-endo-Hydroxybicyclo[3.3.0]oct-2-en-4-ones

Yeh-Long Chen; Chi-Kang Chang; Nein-Chen Chang


Journal of The Chinese Chemical Society | 1997

Total Synthesis of (±)-Patriscabrol and (±)-Boschnialactone

Jiun‐Yuh Chiu; Chih‐Tsao Chiu; Nein-Chen Chang

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