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Dive into the research topics where Nicola U. Zitzmann is active.

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Featured researches published by Nicola U. Zitzmann.


Journal of Clinical Periodontology | 2008

Definition and prevalence of peri-implant diseases.

Nicola U. Zitzmann; Tord Berglundh

OBJECTIVES The aim of the current review was to describe the prevalence of peri-implant diseases including peri-implant mucositis and peri-implantitis. MATERIAL AND METHODS A MEDLINE search (PubMed) until December 2007 was conducted and different keywords related to the prevalence of peri-implant diseases were used. Cross-sectional and longitudinal studies including > or =50 implant-treated subjects exhibiting a function time of > or =5 years were considered. RESULTS AND CONCLUSION The current review revealed that only a few studies provided data on the prevalence of peri-implant diseases. Cross-sectional studies on implant-treated subjects are rare and data from only two study samples were available. Peri-implant mucositis occurred in approximately 80% of the subjects and in 50% of the implants. Peri-implantitis was found in 28% and > or =56% of subjects and in 12% and 43% of implant sites.


Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology | 1998

Sinus elevation procedures in the resorbed posterior maxilla. Comparison of the crestal and lateral approaches.

Nicola U. Zitzmann; Peter Schärer

OBJECTIVES The purpose of this study was to compare three different methods for sinus elevation: (1) the lateral antrostomy as a two-step procedure, (2) the lateral antrostomy as a one-step procedure, and (3) the osteotome technique with a crestal approach. Indication criteria were defined, based on the residual bone height measured from computed tomography scans, for the sake of applying the appropriate technique. STUDY In 30 patients designated for implant treatment in the resorbed posterior maxilla, 79 implants were placed in combination with a bone-grafting material for sinus augmentation. The final bone heights were measured from panoramic radiographs or post-operative computed tomography scans. RESULTS The success rate for the osteotome technique was 95% during the 30-month study period; no failures occurred in any site treated with a lateral antrostomy. The gain in bone height was comparable for the one-step (median = 10 mm) and two-step (median = 12.7 mm) lateral antrostomies. These sites exhibited a significantly greater increase in bone height (p < 0.001) than did the sites in which the osteotome technique was applied (mean = 3.5 mm). The histologic sections showed both bone apposition in intimate contact with the bone-grafting material particles and initial signs of its remodeling. CONCLUSIONS The results indicate that the osteotome technique can be recommended when more than 6 mm of residual bone height is present and an increase of about 3 to 4 mm is expected. In cases of more advanced resorption a one-step or two-step lateral antrostomy has to be performed.


Journal of Prosthetic Dentistry | 1999

Treatment plan for restoring the edentulous maxilla with implant-supported restorations: Removable overdenture versus fixed partial denture design

Nicola U. Zitzmann; Carlo P. Marinello

STATEMENT OF PROBLEM Restoring the edentulous maxilla with a fixed complete denture or a removable overdenture is a complex and challenging procedure. PURPOSE This article presents and discusses the crucial factors involved in deciding whether a fixed or removable implant prosthesis should be planned in fulfilling the patients preference for optimal esthetics, phonetics, comfort, and function. METHODS AND MATERIAL A concept for treatment planning is presented that enables the practitioner to check the decisive parameters during the first examination and to make the final decision with the help of the reformatted computerized tomography scan. CONCLUSION If this treatment plan is followed, implants can be placed to comply with the selected prosthetic solution and compromised solutions can be avoided. The fixed design for implant prosthesis is only appropriate for patients with minimal resorption of the alveolar bone and an optimal maxillomandibular relationship. The removable overdenture may be indicated from the outset and is no longer restricted to patients with a compromised situation in which fixed implant prostheses are not feasible.


Journal of Clinical Periodontology | 2015

Primary prevention of peri-implantitis: managing peri-implant mucositis

Søren Jepsen; Tord Berglundh; Robert J. Genco; Anne Merete Aass; Korkud Demirel; Jan Derks; Elena Figuero; Jean Louis Giovannoli; Moshe Goldstein; Alberto Ortiz-Vigón; Ioannis Polyzois; Giovanni Edoardo Salvi; Frank Schwarz; Giovanni Serino; Cristiano Tomasi; Nicola U. Zitzmann

AIMS Over the past decades, the placement of dental implants has become a routine procedure in the oral rehabilitation of fully and partially edentulous patients. However, the number of patients/implants affected by peri-implant diseases is increasing. As there are--in contrast to periodontitis--at present no established and predictable concepts for the treatment of peri-implantitis, primary prevention is of key importance. The management of peri-implant mucositis is considered as a preventive measure for the onset of peri-implantitis. Therefore, the remit of this working group was to assess the prevalence of peri-implant diseases, as well as risks for peri-implant mucositis and to evaluate measures for the management of peri-implant mucositis. METHODS Discussions were informed by four systematic reviews on the current epidemiology of peri-implant diseases, on potential risks contributing to the development of peri-implant mucositis, and on the effect of patient and of professionally administered measures to manage peri-implant mucositis. This consensus report is based on the outcomes of these systematic reviews and on the expert opinion of the participants. RESULTS Key findings included: (i) meta-analysis estimated a weighted mean prevalence for peri-implant mucositis of 43% (CI: 32-54%) and for peri-implantitis of 22% (CI: 14-30%); (ii) bleeding on probing is considered as key clinical measure to distinguish between peri-implant health and disease; (iii) lack of regular supportive therapy in patients with peri-implant mucositis was associated with increased risk for onset of peri-implantitis; (iv) whereas plaque accumulation has been established as aetiological factor, smoking was identified as modifiable patient-related and excess cement as local risk indicator for the development of peri-implant mucositis; (v) patient-administered mechanical plaque control (with manual or powered toothbrushes) has been shown to be an effective preventive measure; (vi) professional intervention comprising oral hygiene instructions and mechanical debridement revealed a reduction in clinical signs of inflammation; (vii) adjunctive measures (antiseptics, local and systemic antibiotics, air-abrasive devices) were not found to improve the efficacy of professionally administered plaque removal in reducing clinical signs of inflammation. CONCLUSIONS Consensus was reached on recommendations for patients with dental implants and oral health care professionals with regard to the efficacy of measures to manage peri-implant mucositis. It was particularly emphasized that implant placement and prosthetic reconstructions need to allow proper personal cleaning, diagnosis by probing and professional plaque removal.


Journal of Prosthetic Dentistry | 2010

Strategic considerations in treatment planning: Deciding when to treat, extract, or replace a questionable tooth

Nicola U. Zitzmann; Gabriel Krastl; Hanjo Hecker; Clemens Walter; Tuomas Waltimo; Roland Weiger

Prosthodontists face the difficult task of judging the influence and significance of multiple risk factors of periodontal, endodontic, or prosthetic origin that can affect the prognosis of an abutment tooth. The purpose of this review is to summarize the critical factors involved in deciding whether a questionable tooth should be treated and maintained, or extracted and possibly replaced by dental implants. A MEDLINE (PubMed) search of the English, peer-reviewed literature published from 1966 to August 2009 was conducted using different keyword combinations including treatment planning, in addition to decision making, periodontics, endodontics, dental implants, or prosthodontics. Further, bibliographies of all relevant papers and previous review articles were hand searched. Tooth maintenance and the acceptance of risks are suitable when: the tooth is not extensively diseased; the tooth has a high strategic value, particularly in patients with implant contraindications; the tooth is located in an intact arch; and the preservation of gingival structures is paramount. When complete-mouth restorations are planned, the strategic use of dental implants and smaller units (short-span fixed dental prostheses), either tooth- or implant-supported, as well as natural tooth abutments with good prognoses for long-span FDPs, is recommended to minimize the risk of failure of the entire restoration.


Journal of Clinical Periodontology | 2009

Three‐dimensional imaging as a pre‐operative tool in decision making for furcation surgery

Clemens Walter; Doğan Kaner; Dorothea C. Berndt; Roland Weiger; Nicola U. Zitzmann

AIM To investigate the use of cone beam computed tomography (CBCT) in assessing furcation involvement (FI) and concomitant treatment decisions in maxillary molars. MATERIAL AND METHODS Twelve patients with generalized chronic periodontitis were consecutively recruited and CBCT was performed in maxillary molars (n=22) with clinical FI and increased probing pocket depths. CBCT images were analysed and FI, root length supported by bone and anatomical features were evaluated. FI and treatment recommendations based on clinical examinations and periapical radiographs were compared with data derived from CBCT images. RESULTS The estimated degree of FI based on clinical findings was confirmed in 27% of the sites, while 29% were overestimated and 44% revealed an underestimation according to CBCT analyses. Among degree I FI, 25% were underestimated, among degree II and II-III, the underestimation was as high as 75%, while all sites with degree III FI were confirmed in the CBCT. Discrepancies between clinically and CBCT-based therapeutic treatment approaches were found in 59-82% of the teeth, depending on whether the less invasive or the most invasive treatment recommendation was selected for comparison. CONCLUSIONS CBCT images of maxillary molars may provide detailed information of FI and a reliable basis for treatment decision.


Journal of Clinical Periodontology | 2010

Accuracy of three-dimensional imaging in assessing maxillary molar furcation involvement

Clemens Walter; Roland Weiger; Nicola U. Zitzmann

AIM To assess the accuracy of cone beam computed tomography (CBCT) in detecting furcation involvement (FI) in maxillary molars. MATERIAL AND METHODS Fourteen patients with generalized advanced chronic periodontitis were consecutively recruited and treated non-surgically. In maxillary molars considered for furcation surgery due to increased FI and/or increased probing pocket depths during re-evaluation, CBCT was performed and the degree of FI was evaluated from the CBCT images. Furcation surgery was performed in 25 maxillary molars. Intra-surgical FI assessments were compared with data derived from CBCT images. RESULTS Overall, 84% of the CBCT data were confirmed by the intra-surgical findings (weighted kappa=0.926, 95% confidence interval: 0.681-1.0). While 14.7% (11 sites) were underestimated (CBCT less than intra-surgical value), in only 1.3% (one site) did the CBCT data lead to an overestimation compared with the intra-surgical analysis. The agreement between both assessments was the highest in distopalatal furcation entrances, followed by buccal and mesiopalatal. CONCLUSIONS CBCT images demonstrate a high accuracy in assessing the loss of periodontal tissue and classifying the degree of FI in maxillary molars.


International Endodontic Journal | 2009

Influence of post fit and post length on fracture resistance

Leonard Büttel; Gabriel Krastl; H. Lorch; M. Naumann; Nicola U. Zitzmann; Roland Weiger

AIM To investigate (i) the impact of post fit (form-congruence) and (ii) the influence of post length on the fracture resistance of severely damaged root filled extracted teeth. METHODOLOGY Ninety-six single-rooted human teeth were root filled and divided into four groups (n = 24 per group). Post spaces were prepared with a depth of 6 mm (group 1, 3) and 3 mm (group 2, 4). Form-congruence with a maximal fit of the post within the root canal space was obtained in groups 1 and 2, whereas there was no form-congruence in groups 3 and 4. In all groups, glass fibre reinforced composite (FRC) posts were adhesively cemented and direct composite crown build-ups were fabricated without a ferrule. After thermo-mechanical loading (1200000x, 5-50 degrees C), static load was applied until failure. Loads-to-failure [in N] were compared amongst the groups. RESULTS Post fit did not have a significant influence on fracture resistance, irrespective of the post length. Both groups with post insertion depths of 6 mm resulted in significantly higher mean failure loads (group 1, 394 N; group 3, 408 N) than the groups with post space preparation of 3 mm (group 2, 275 N; group 4, 237 N). CONCLUSIONS Within the limitations of this study, the fracture resistance of teeth restored with FRC posts and direct resin composite crowns without ferrules was not influenced by post fit within the root canal. These results imply that excessive post space preparation aimed at producing an optimal circumferential post fit is not required to improve fracture resistance of roots.


Journal of Clinical Periodontology | 2012

Clinical research in implant dentistry: evaluation of implant-supported restorations, aesthetic and patient-reported outcomes.

Niklaus P. Lang; Nicola U. Zitzmann

The articles discussed in working group 3 dealt with specific aspects of clinical research. In this context, the literature reporting on survival and complication rates of implant-supported or implant-tooth supported restorations in longitudinal studies of at least 5 years were discussed. The second aspect dealt with the evaluation of aesthetic outcomes in clinical studies and the related index systems available. Finally, the third aspect discussed dealt with patient-reported outcome measures (PROMs). A detailed appraisal of the available methodology was presented.


European Journal of Oral Sciences | 2008

Changes in oral health over a 10-yr period in Switzerland.

Nicola U. Zitzmann; Katharina Staehelin; A.W.G. Walls; Giorgio Menghini; Roland Weiger; Elisabeth Zemp Stutz

The Swiss Health Surveys are conducted every 5 yr, and alternate surveys contain information on oral health. Worldwide the population is ageing and oral health is improving. The aim of this study was to identify if these trends are continuing in a relatively affluent society with low levels of edentulousness. Participants in the 1992 and 2002 surveys completed a written questionnaire including items on oral health (response rates 75% and 86% respectively). Data were weighted and bivariate analyses were performed to calculate the average number of missing teeth and the prevalence of different prosthetic dental restorations for each cohort. Over the 10-yr period the proportion of subjects retaining all natural teeth increased, and the mean number of teeth increased, on average, by 1.3. Among those who required prosthetic dental restorations, fixed restorations increased and complete denture use was reduced. Strikingly, 4.4% of this sample reported having oral implants in 2002. Greater numbers of missing teeth and a higher prevalence of use of removable prostheses were still seen in women, in those who had only completed compulsory education, in subjects from families with low income, in those who smoke, and in those who were overweight, in 2002.

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Tord Berglundh

University of Gothenburg

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