Nikolaos G. Argyropoulos

Synthesis of unsymmetrical 1,1'-disubstituted ferrocenes. Formation of ferrocenophanes via intramolecular cycloaddition

Abstract Unsymmetrical 1,1′-disubstituted ferrocenes bearing appropriate substituents for intramolecular cycloadditions were synthesized conveniently starting from 1,1′-ferrocenedicarbaldehyde. Ferrocenenitrone derivatives reacted in an intramolecular regioselective manner affording ferrocenophanes.

Application of Chiral Cyclic Nitrones to the Diastereoselective Synthesis of Bicyclic Isoxazolidine Nucleoside Analogues

New bicyclic isoxazolidine nucleoside analogues are synthesized through 1,3-dipolar cycloaddition of enantiopure cyclic nitrones to appropriate vinyl nucleobases. The reactions are diastereoselective, giving as the main or the sole product the exo-Re cycloadducts. The diastereoselectivity depends on both the kind of the base and the substitution pattern of the nitrone.

1,3‐DIPOLAR CYCLOADDITION REACTIONS OF NITRILE OXIDES WITH 2‐METHYLTHIOVINYL PHENYL KETONE

Les reactions du titre conduisent regioselectivement a des benzoyl-4 oxazolines-2; ceci est en accord avec des predictions theoriques a partir de la theorie FMO