Nobuko Hashiguchi

Cutaneous Warm and Cool Sensation Thresholds and the Inter-threshold Zone in Malaysian and Japanese Males

The purpose of this study was to investigate ethnic differences in cutaneous thermal sensation thresholds and the inter-threshold sensory zone between tropical (Malaysians) and temperate natives (Japanese). The results showed that (1) Malaysian males perceived warmth on the forehead at a higher skin temperature (Tsk) than Japanese males (p<0.05), whereas cool sensations on the hand and foot were perceived at a lower Tsk in Malaysians (p<0.05); (2) Overall, the sensitivity to detect warmth was greater in Japanese than in Malaysian males; (3) The most thermally sensitive body region of Japanese was the forehead for both warming and cooling, while the regional thermal sensitivity of Malaysians had a smaller differential than that of Japanese; (4) The ethnic difference in the inter-threshold sensory zone was particularly noticeable on the forehead (1.9±1.2C for Japanese, 3.2±1.6°C for Malaysians, p<0.05). In conclusion, tropical natives had a tendency to perceive warmth at a higher Tsk and slower at an identical speed of warming, and had a wider range of the inter-threshold sensory zone than temperate natives.

Gender differences in thermal comfort and mental performance at different vertical air temperatures

The purpose of this study was to investigate the effects of a thermal environment where air temperature closer to the ground was lower compared to that above on thermal comfort and mental performance in both sexes. Temperatures at the upper and lower parts of the body were controlled independently using a climatic box placed in a climatic chamber. Sixteen healthy subjects (8 males and 8 females) were exposed to the four conditions with various temperature differences between the upper (25°C) and lower part of the body (16, 19, 22, or 25°C). Skin temperature and subjective votes were measured, and two kinds of task using a computer were performed during exposure. Skin temperature on the back for females was higher than that for males during exposure, and the decrease in thigh skin temperature for females under lower air temperature conditions was significantly larger than that for males. A significant difference in thermal comfort at the beginning of the exposure was indicated between genders, especially in the 16 and 19°C conditions, so females became aware of thermal discomfort before males. Although the score of mental performance based on perceptual speed for females was higher than that for males, there was no significant effect from the different vertical air temperatures. The effect of the unequal thermal environment, where air temperature closer to the ground was lower than above, on skin temperature and thermal discomfort for females was significantly higher compared to males.

Ethnic differences in thermoregulatory responses during resting, passive and active heating: application of Werner’s adaptation model

For the coherent understanding of heat acclimatization in tropical natives, we compared ethnic differences between tropical and temperate natives during resting, passive and active heating conditions. Experimental protocols included: (1) a resting condition (an air temperature of 28°C with 50% RH), (2) a passive heating condition (28°C with 50% RH; leg immersion in a hot tub at a water temperature of 42°C), and (3) an active heating condition (32°C with 70% RH; a bicycle exercise). Morphologically and physically matched tropical natives (ten Malaysian males, MY) and temperate natives (ten Japanese males, JP) participated in all three trials. The results saw that: tropical natives had a higher resting rectal temperature and lower hand and foot temperatures at rest, smaller rise of rectal temperature and greater temperature rise in bodily extremities, and a lower sensation of thirst during passive and active heating than the matched temperate natives. It is suggested that tropical natives’ homeostasis during heating is effectively controlled with the improved stability in internal body temperature and the increased capability of vascular circulation in extremities, with a lower thirst sensation. The enhanced stability of internal body temperature and the extended thermoregulatory capability of vascular circulation in the extremities of tropical natives can be interpreted as an interactive change to accomplish a thermal dynamic equilibrium in hot environments. These heat adaptive traits were explained by Wilder’s law of initial value and Werner’s process and controller adaptation model.

Effects of low humidity and high air velocity in a heated room on physiological responses and thermal comfort after bathing : An experimental study

OBJECTIVE In the present study we investigated the effects of low relative humidity (RH) and high air velocity (VA) on physiological and subjective responses after bathing in order to present the evidence for required nursing intervention after bathing. METHODS Eight healthy male subjects participated in this experiment. There were four thermal conditions which combined RH (20% of 60%) and VA (low: less than 0.2 m/s or high: from 0.5 to 0.7 m/s). After taking a tub bath, subjects sat for 80 min in the test room under each condition. In addition, one condition under which the subjects were exposed to 20% RH and high VA condition for 80 min without bathing condition was conducted. RESULTS A decrease in mean skin temperature (T sk), dryness of the skin and eyes were observed, though thermal comfort and warmth retained, due to spending time after bathing in a low RH and high VA environment, compared to the condition without bathing. Moreover, dryness of the skin, a decrease in hydration of the skin and an increase in transepidermal water loss (TEWL) after bathing were significantly affected by RH levels, on the other hand subjective coolness, discomfort and perception of dryness in the eye were significantly affected by VA levels. The decrease in T sk after bathing was significantly affected by both RH and VA. CONCLUSION From our findings we concluded that low RH and high VA have negative effects on humans after bathing, for example a decrease in body temperature and dryness of the skin and eyes. Moreover, it was indicated that the negative effects could be kept to a minimum and thermal comfort remain higher, if RH and VA levels were controlled within the optimum ranges.

Influence of primary and secondary prevention indications on anxiety about the implantable cardioverter-defibrillator

Implantable cardioverter‐defibrillators (ICDs) have been established for primary and secondary prevention of fatal arrhythmias. However, little is known about the influence of ICD indications on quality of life (QOL) and psychological disturbances. This study aimed to examine whether there were differences in QOL and psychological distress in patients that have an ICD for primary or secondary prevention of fatal arrhythmias.

Different Physiological and Subjective Responses to the Hyperthermia Between Young and Older Adults: Basic Study for Thermal Therapy in Cardiovascular Diseases

BACKGROUND Thermal therapy has been used as adjuvant therapy in patients with cardiovascular disease. However, little is known about responses to thermal stress in older adults. We examined the effects of thermal stress in younger and older healthy Japanese individuals. METHODS The study included 12 young (mean age, 22 years) and 12 older (mean age, 68 years) healthy adults and was performed under strict temperature and humidity control to minimize confounding. Participants lay supine throughout three consecutive 30-minute phases: Phase I (heating at 70°C in a dome-shaped sauna), Phase II (insulation in the sauna), and Phase III (cool down). Physiological parameters and subjective thermal sensations were compared within and between two age groups. RESULTS Mean skin temperature increased significantly in both age groups (Phase I) and after the first 10 minutes was higher among older adults (by 6.8°C vs 6.0°C among younger; p < .01). Mean rectal temperature increased by 0.6°C in both groups (Phase II). Mean heart rate increased significantly in both age groups (Phase II) and was higher among younger adults (by 21.4 vs 11.3 beats/min among older adults; p < .05). Both systolic (by 15.1 mmHg) and diastolic (by 10.5 mmHg) blood pressure dropped significantly among older adults (Phase I), returning to baseline in Phase III; no changes were noted among those younger. There was no between-group difference in fluid loss or thermal sensations. CONCLUSIONS Compared with younger adults, older adults are more likely to drop blood pressure in response to thermal stress but had similar fluid loss and subjective responses.

Cardiac and respiratory effects of deep regional hyperthermia using an 8 MHz radiofrequency-capacitive device on patients with cancer

Abstract Purpose: Hyperthermia (HT), an adjuvant therapy for variable cancers, may cause physiological changes in the patients, which may lead to cardiovascular problems. Among various HT treatments, the physiological effects of deep regional HT are still unclear. We examined the physiological alterations throughout deep regional HT to improve the HT safety. Materials and methods: Thirty-one patients (age: 61 ± 12 years) with cancer received HT in the thoracic or upper abdominal regions using an 8-MHz radiofrequency-capacitive-device for 50 min. Rectal temperature (Trec), systolic and diastolic blood pressures (SBP and DBP), pulse rate (PR), respiratory rate (RR), percutaneous oxygen saturation (SpO2) and sweating volume were evaluated throughout HT. Results: At 50 min after starting HT, Trec, PR and RR were significantly increased compared with the baseline values (Trec: 38.2 ± 1.4 vs. 36.3 ± 0.8 °C, p < 0.001, PR: 104 ± 15 vs. 85 ± 16 bpm, p < 0.05, RR: 23 ± 3 vs. 21 ± 3/min, p < 0.05). Although the average SBP and DBP were both stable during HT in a recumbent position, these values dropped significantly in a standing position (SBP: 113 ± 16 vs. 127 ± 18 mmHg, p < 0.001, DBP: 70 ± 12 vs. 75 ± 13 mmHg, p < 0.01). The total amount of sweating was 356 ± 173 g/m2 on average. Conclusions: Deep regional HT increased the deep body temperature and resulted in an increase of sweating with peripheral vasodilatation. Consequently, a significant reduction in BP would be induced on standing after HT. Careful attention is needed for patients receiving HT, especially when standing after HT.

Left Ventricular Ejection Fraction Predicts Severity of Posttraumatic Stress Disorder in Patients With Implantable Cardioverter-Defibrillators.

Implantable cardioverter‐defibrillators (ICD) have provided effective therapy for fatal arrhythmia. However, ICD patients are known to develop psychological problems, such as posttraumatic stress disorder (PTSD), if they have experienced potentially fatal arrhythmia and ICD shocks. Little is known about the factors influencing PTSD in ICD patients.

A Nationwide Cross-sectional Study on Congenital Heart Diseases and Symptoms of Sleep-disordered Breathing among Japanese Down's Syndrome People

OBJECTIVE It is well known that people with Downs syndrome (DS) frequently complicate with congenital heart diseases (CHDs). Patients with heart diseases often have sleep-disordered breathing as a co-morbidity (SDB) which worsens the heart diseases. However, the relationship between SDB and CHDs in DS people has not yet been fully elucidated. The aim of this study was to establish the association between SDB and CHDs in DS people using data from a large nationwide questionnaire survey in Japan. METHODS We conducted a cross-sectional questionnaire survey of a randomly selected sample of 2,000 DS people and their caregivers throughout Japan to examine the associations between observed signs of SDB and CHDs in DS people. The questionnaire included the presence of SDB symptoms (snoring, apnea, arousal, nocturia, and napping) and CHDs (the presence and types of CHDs). RESULTS Of the 1,222 replies received from the caregivers, 650 reported complications of some type of CHDs. The observed apnea tended to be higher among DS people with CHDs than those without CHDs (OR=1.28, 95% CI=0.97-1.70, p=0.09). DS people with tetralogy of Fallot reported significantly more frequent apnea than those without CHDs (OR=3.10, 95% CI=1.36-7.05, p<0.01). CONCLUSION SDB prevailed among DS people with severe CHDs, such as tetralogy of Fallot. Careful attention to the signs of SDB in such patients may lead to earlier clinical intervention removing the vicious cycle between SDB and CHDs.

Effects of bathroom temperature on thermal responses during whole-body bathing, half-body bathing and showering

Abstract This study examined the effect of bathroom thermal conditions on physiological and subjective responses before, during and after three kinds of bathing. Bathing methods were as follows: whole-body bath (W-bath), half-body bath (H-bath) and showering. The air temperature of the dressing room and bathroom was kept at 10, 17.5 and 25°C. Eight healthy males bathed for 10 min under nine conditions on separate days. Water temperature of the bathtub and shower was kept at 40 or 41°C, respectively. Rectal temperature ( T re ), skin temperature ( T sk ), blood pressure (BP), heart rate (HR), body weight loss and blood characteristics (hematcrit: Hct) were measured. Thermal sensation (TS) and thermal comfort (TC) were also recorded. During bathing, BP decreased rapidly during W-bath and H-bath, and HR during a W-bath was significantly higher than during a H-bath or showering. The double products (systolic blood pressure × heart rate) due to W-bath during bathing were also greater than for a H-bath and showering. There was no distinct difference in Ht among the nine conditions. However, significant differences in body weight loss were observed among the bathing methods: W-bath > H-bath > showering. The changes in T re after a H-bath at 25°C were similar to those of W-bath at 17.5 and 10°C. The large differences in T re were due to the room temperature for the H-bath. TS and TC after bathing significantly differed with the three kinds bathing at 17.5 and 10°C. Especially with showering, TS and TC were significantly cooler and more uncomfortable than W-bath and H-bath. These results suggest that the physiological strains of a H-bath and showering were less than a W-bath. However, it is particularly important with a H-bath and showering to maintain an acceptable temperature in the dressing room and bathroom, in order to bathe comfortably and keep the body warm.