Nobuo Fujieda

EXPERIMENTAL STUDY OF MICROWAVE COAGULATION OF A VX-2 CARCINOMA IMPLANTED IN RABBIT KIDNEY

This paper describes the results of an experimental study of the microwave coagulation of VX‐2 renal tumors implanted in rabbits. The rabbits undergoing microwave treatment exhibited a satisfactory survival rate and a complete response to treatment, as verified by histological examination. All the rabbits receiving no treatment died within 6 weeks of implantation of the VX‐2 carcinoma. These results indicate that microwave coagulation may be a curative method of treatment for a relatively small renal tumor. Intraoperative real‐time ultrasonic scanning permits the percutaneous microwave coagulation of renal cancer in a clinical situation.

Urinary basic fetoprotein in the diagnosis and follow‐up of patients with urothelial carcinoma

Urothelial carcinoma is one of the most common malignant neoplasms of the urinary tract and is characterized by a high local recurrence rate. However, no specific and reliable tumor marker has been identified for the diagnosis and follow‐up of patients with urothelial carcinoma.

A case of transurethral microwave coagulation therapy for urinary bladder diverticulum

We applied transurethral microwave coagulation therapy to urinary bladder diverticulum. The case is 71-year-old female who had two large diverticulums, 11 × 9 × 7 cm in size on the right lateral wall and 5 × 5 × 4 cm in size on the anterior wall. Electrode resection of diverticular neck was performed, and then all of the inside mucosa was coagulated with a microwave energy of 100 watts. This procedure was able to be performed safely to the end without any complications. After the operation, both diverticulums disappeared. It supposed that the transurethral microwave coagulation therapy was a useful procedure for the endoscopic treatment of urinary bladder diverticulum.

Microwave regional coagulation therapy for outpatients with recurrent, superficial bladder cancer

From April 1988 to June 1995, we performed microwave regional coagulation therapy (MRCT) with suspicious recurrent bladder tumors, immediately after bladder biopsy under epidural anesthesia 24 times in 17 outpatients. Of the 17 cases, both clinical and pathological examinations revealed that 14 cases were of recurrent, superficial bladder cancer. Tumors were completely eradicated both endoscopically and histologically in all patients. Four had a slight hematuria or lower abdominal pain after MRCT. These complications, however, improved in a few days after medication. Furthermore, the cost of outpatient MRCT was one third that of the transurethral resection of bladder tumor in hospital treatment, which required a 3 day admission. Outpatient MRCT could be one of several safe and useful treatments for patients with recurrent bladder cancer.