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Nobuo Nagashima

Kaneka Corporation

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Publication

Featured researches published by Nobuo Nagashima.

Tetrahedron Letters | 1998

A HIGHLY EFFICIENT ASYMMETRIC SYNTHESIS OF METHOXYHOMOPHENYLALANINE USING MICHAEL ADDITION OF PHENETHYLAMINE

Masahiko Yamada; Nobuo Nagashima; Junzo Hasegawa; Satomi Takahashi

Abstract A practical method for (S)-p -methoxyhomophenylalanine ( S )- 1 by using diastereoselective Michael addition as a key step was reported. Thus, the Michael addition of ( S )- 1 -phenethylamine ( S )- 3 to p -methoxy- trans -benzoylacrylic acid 2 was performed in a highly stereoselective (up to 98% d.e. and up to 90% yield) fashion and, subsequently, the resultant adduct 4a was catalytically hydrogenated to afford ( S )- 1 almost quantitatively. The most likely mechanism of the addition reaction was dynamic resolution.

Journal of Molecular Catalysis B-enzymatic | 2008

Characterization of novel alcohol dehydrogenase of Devosia riboflavina involved in stereoselective reduction of 3-pyrrolidinone derivatives

Noriyuki Kizaki; Yoshihiko Yasohara; Nobuo Nagashima; Junzo Hasegawa

Archive | 2007

Process for production of optically active 3-amino-2 -hydroxypropionic cyclopropylamide derivatives and salts thereof

Kohei Mori; Akira Nishiyama; Naoaki Taoka; Daisuke Moriyama; Nobuo Nagashima

Archive | 2000

Process for producing optically active azetidine-2-carboxylic acids

Tatsuya Honda; Nobuo Nagashima

Tetrahedron Letters | 2007

Enantioselective synthesis of D-and L-α-methylcysteine with hydantoinase

Takahiro Ohishi; Hirokazu Nanba; Masanobu Sugawara; Masashi Izumida; Tatsuya Honda; Kohei Mori; Satohiro Yanagisawa; Makoto Ueda; Nobuo Nagashima; Kenji Inoue

Archive | 2005

Processes for Producing Optically Active 1-Substituted 2-Methylpyrrolidine and Intermediate Therefor

Akira Nishiyama; Naoaki Taoka; Narumi Kishimoto; Nobuo Nagashima

Archive | 2000

Process for the preparation of 3-hydroxytetrahydrofuran

Koichi Kinoshita; Tadashi Moroshima; Yoshifumi Yanagida; Nobuo Nagashima; Yasuhiro Saka; Tatsuya Honda; Yoshihide Fuse; Yasuyoshi Ueda

Archive | 2005

Process for producing optically active beta-amino alcohol

Akira Nishiyama; Narumi Kishimoto; Nobuo Nagashima

Archive | 2003

PROCESS FOR PRODUCING OPTICALLY ACTIVE s-AMINO ALCOHOL

Akira Nishiyama; Narumi Kishimoto; Nobuo Nagashima

Archive | 2004

Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative

Tatsuyoshi Tanaka; Masanobu Sugawara; Hirofumi Maeda; Akira Nishiyama; Yoshihiko Yoshohara; Nobuo Nagashima

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Akira Nishiyama

Kaneka Corporation

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Narumi Kishimoto

Kaneka Corporation

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Junzo Hasegawa

Kaneka Corporation

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Masanobu Sugawara

Kaneka Corporation

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Tatsuya Honda

Kaneka Corporation

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Kenji Inoue

Kaneka Corporation

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Kohei Mori

Kaneka Corporation

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Masahiko Yamada

Kaneka Corporation

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Naoaki Taoka

Kaneka Corporation

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Hirokazu Nanba

Kaneka Corporation

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