Nupur Agarwal

Recurrent bimaxillary radiopacities: A rare case report

Cemento-ossifying fibroma (COF) is considered a benign osseous tumor. Herewith, we present a case of multiple central ossifying fibroma in a 35-yeaold woman. Intraorally, there was swelling in the left upper posterior teeth region and another diffused swelling in the fourth quadrant. Radiographs revealed the presence of well-defined mixed radiolucent-radiopaque area having thin radiolucent rim followed by thick sclerotic margin. No genetic correlation could be established. As bilateral COF is a rare entity, we present such a case with different radiographic appearance, using various radiographic techniques.

Sjogren's syndrome: A review

Sjogrens syndrome (SS) is a chronic autoimmune disease characterized by the lymphocytic infiltration of salivary and lacrimal glands leading to xerostomia and keratoconjunctivitis sicca. Prevalence of primary SS in the general population has been estimated to be around 1-3%. SS is an under-recognized disease in which most of the significant progress has been made in the past 25 years. The herald of newer diagnostic tools could help clinicians and thereby provide significant relief to patients through earlier treatments. The treatment of SS is limited to symptomatic management, and involves the use of solutions to replace salivary secretion and afford a measure of hydration. The purpose of present paper is to highlight the difficulties and complexities that are inherent in the diagnosis of SS and the important role that dental practitioners can play in the management of its oral manifestations.

Hypohidrotic Ectodermal Dysplasia (ED): A Case Series.

ECTODERMAL DYSPLASIA (ED) IS A RARE DISORDER WITH DEFECTS IN TWO OR MORE OF THE FOLLOWING STRUCTURES: the teeth and the skin and its appendages including hair, nails, eccrine, and sebaceous glands. Dental manifestations include hypodontia, complete anodontia or malformed teeth. The most common form of the ED syndrome is hypohidrotic ED and is usually inherited as an X-linked recessive trait. Female carriers may have a variable degree of clinical manifestations. The condition is thought to occur in approximately 1 in every 100,000 live births. Dental treatment for these patients varies on an individual basis. Children with ED are often treated dentally with conventional adult appearing prosthesis which are focused only on the oral manifestations of the syndrome. We are here reporting two classical cases of hypohidrotic ED with a review of the literature.

Estimation of serum lipids in patients with Oral Submucous Fibrosis in India.

Objectives: Oral submucous fibrosis (OSMF) is the most prevalent precancerous condition in India. Low levels of lipids serves as a marker and prognostic indicator in the early detection of oral precancerous and cancerous states. In spite of the high prevalence and its potential to undergo malignant transformation, this condition has not widely been investigated with respect to the serum lipid levels. In the present study, an attempt was made to analyze the complete serum lipid profile, total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol and very low density lipoprotein (VLDL) cholesterol in OSMF and controls. Material and Methods: The study was conducted in 45 clinically and histopathologically diagnosed cases of OSMF and 45 age and sex matched controls. The complete lipid profile including TC, TG, HDL cholesterol, LDL cholesterol and VLDL cholesterol was analyzed. Results: The serum lipid levels were significantly lower in the patients with OSMF than in the controls. When the values were compared between different disease stages, the maximum reduction of lipids was evident for stage 3 OSMF. From the present results, it is evident that the level of serum lipids decreases with progression of the disease. Conclusions: From these findings, it appears that the decrease in the lipid levels may be considered as a useful marker in the early diagnosis of oral premalignant condition like OSMF. Key words:Oral submucous fibrosis, lipids, premalignant condition.

Ameloblastic Carcinoma: A Case Report

Ameloblastic carcinoma is a rare malignant lesion with characteristic histologic features and behavior that dictates more aggressive surgical approach than that of a simple ameloblastoma. Here we present a case of ameloblastic carcinoma of the mandible in a 30-year-old male patient with a clinical course of typical aggressiveness and extensive local destruction.

Prevalence of Zygomatic Air Cell Defect using Orthopantomogram.

AIM To determine the prevalence, radiographic appearance, variations, characteristics and establishing dominant location and type of zygomatic air cell defect (ZACD) among the North Indian population. MATERIALS AND METHODS The panoramic radiographs of 2500 dental clinic outpatients were examined for the presence of ZACD for estimating the prevalence and characteristics of the ZACD. RESULTS ZACD was found in 63 patients with a prevalence of 2.5% with male predominance. Unilateral (70%) and unilocular appearance (78%) of ZACD were the dominant patterns. Patients with ZACD had a mean age of 37.4 years and a range of 19-78 years. CONCLUSION The prevalence of ZACD among the Indian population is in accordance with the other studies carried out in other populations of the world. So it is important for surgeons to assess location of ZACD before planning any surgical procedure in order to avoid intraoperative complications.

Oral Soft Tissue Metastasize Ovarian Malignancy, Way to Other Hidden Malignancies: A Rare Case Report

The metastasis of malignant tumors within the oral cavity always remains a rare clinical entity. Most metastatic tumors have the propensity for involving the mandible rather than the other oral soft tissues structures. Within, we describe an unusual case of ovarian malignancy that metastasized to the mandibular and involved the mandibular gingiva as an initial manifestation, and as per our best knowledge this is the second reported case until now. There is limited erudition regarding ovarian cancer metastatic and involving the oral cavity.

Oral diagnostics: an integral component to geriatric health care.

Abstract Aging is inevitable, every day we live we age. The mouth is referred to as a mirror of overall health, reinforcing that oral health is an integral part of general health. Oral health reflects overall well being for the elderly population. Compromised oral health may be a risk factor for systemic diseases commonly occurring in age. Diagnosis and proper treatment is essential for healthy aging. Timely diagnosis, appropriate treatment and regular follow-up of both oral and systemic diseases are a prerequisite for active aging. Oral diagnostics is a revolutionary development with high potential to replace other investigative modalities. Changing demographics, including the increase in life expectancy and the growing numbers of elderly, has focused attention on the need for dental research activities to be expanded for geriatric dentistry. This paper is aimed to shed light on the growing elderly population and their ailments. It also aims to create awareness among health care providers about oral diagnostics and their application in geriatrics.

Nanotechnology: A boon in oral cancer diagnosis and therapeutics

Nanotechnology is rapidly developing subdivision of technology that effects on many fields. Medicine is also influenced by nanotechnology. Nanotechnology modified methods can be used in cancer treatment. Nanotechnology can assist to have better diagnosis with less harmful substance. The use of optical nanoparticles provides efficient drug delivery to tumor cells with liposomes and functionalized micelles. Nanotechnology can be also used in molecular imaging with tomography and photoacoustic imaging of tumors and therapy of cancer as photothermal and radiotherapy. Nanotechnology a next generation techniques have many advantages to treat cancer patients from diagnosis to treatment.