O. P. Tandon

Role of uterine artery velocimetry using color-flow Doppler and electromyography of uterus in prediction of preterm labor

Aim:  To evaluate the role of Doppler waveforms of uterine vessels and electromyography (EMG) of the uterus in predicting preterm labor.

Study of central gray nmda receptors in nociceptive behaviour in rats

Abstract 1. 1. Cannulae were implanted stereotaxically in the PAG area in rats. 2. 2. Nociceptive thresholds were assessed in these rats, by measuring the tail flick latencies after post - operative recovery. 3. 3. Micro-injections of NMDA, L — aspartic acid and L — glutamic acid were made in the central gray and the effects on tail flick latencies studied. 4. 4. Low dose of NMDA in the PAG did not significantly alter the tail flick latencies, higher doses produced hyperalgesia. 5. 5. L — glutamic acid, aspartic acid, and Mk 801 induced hyperalgesia in the doses used. Ketamine did not significantly affect the tail flick latencies.

P36.5 Assessment of cognitive function by P300 event-related potentials in chronic kidney disease

visible stimulation when the figure in the COS stimulation was identical to the target visible stimulus, but more so for the face than flower stimulus. The ERF component modulated by the COS stimulation was estimated to be located in the ventral temporal cortex. Conclusion: We speculated that the enhancement was caused by an interaction of the responses following sub-threshold stimulation by the COS stimulation and the supra-threshold stimulation following target stimulation, such as in the processing for categorization or discrimination. We also speculated that the face was processed with priority at the level of the ventral temporal cortex during visual processing outside of consciousness.

P36.6 Effect of hemodialysis on event-related potentials in ESRD patients

Background: Uremia is associated with impairment of different cognitive functions. However the pathogenesis of this cognitive dysfunction is unknown. Objective: In this study, long-latency event-related potentials (ERPs) were used to assess changes in cortical function due to hemodialysis treatment. Methods: In this cross-sectional study, we measured event-related potentials in 15 end-stage renal disease (ESRD) patients maintained on hemodialysis, two hours before and two hours after they underwent hemodialysis and compared their data with a strictly age and sex matched healthy control group. The P3 was elicited by using standard auditory ‘‘odd-ball’’ paradigm and the data obtained was statistically analyzed (Wilcoxon signed ranks, Mann Whitney). Results: Before hemodialysis, the patients’ P3 latency (47.73 ± 39.47 ms) was significantly increased as compared with that of healthy control group (308.4 ± 13.73 ms) (p = 0.001). After hemodialysis, P3 latency of the patients showed a significant decrease (347.73 ± 39.47–325.20 ± 37.15 ms, p = 0.001). P3 latency after dialysis was not significantly different from controls. No significant correlation was noted between various biochemical parameters (hemoglobin, blood urea, creatinine, uric acid and calcium) and P3 latency or amplitude. Conclusions: Removal of uremic toxins by hemodialysis leads to an improvement in cognitive processing.