Oene R. Veltman
University of Groningen
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Publication
Featured researches published by Oene R. Veltman.
FEBS Letters | 1993
Florence Hardy; Gert Vriend; Oene R. Veltman; B. van der Vinne; G Venema; Vincent G. H. Eijsink
The thermostability of neutral proteases has been shown to depend on autolysis which presumably occurs in flexible regions of the protein. In an attempt to rigidify such a region in the neutral protease of Bacillus stearothermophilus, residues in the solvent‐exposed 63–69 loop were replaced by proline. The mutations caused large positive (Ser‐65 → Pro, Ala‐69 → Pro) or negative (Thr‐63 → Pro, Tyr‐66 → Pro) changes in thermostability, which were explained on the basis of molecular modelling of the mutant proteins. The data show that the introduction of prolines at carefully selected positions in the protein can be a powerful method for stabilization.
FEBS Letters | 1997
Oene R. Veltman; Gert Vriend; Bertus van den Burg; Florence Hardy; Gerard Venema; Vincent G. H. Eijsink
© 1997 Federation of European Biochemical Societies.
Proceedings of the National Academy of Sciences of the United States of America | 1998
Bertus van den Burg; Gert Vriend; Oene R. Veltman; Gerard Venema; Vincent G. H. Eijsink
Protein Engineering | 1992
Vincent G. H. Eijsink; Bauke W. Dijkstra; Gerrit Vriend; J.Rob van der Zee; Oene R. Veltman; B. van der Vinne; B. van den Burg; S. Kempe; G Venema
Protein Engineering | 1996
Oene R. Veltman; Gert Vriend; Pieter J. Middelhoven; Bertus van den Burg; Gerard Venema; Vincent G. H. Eijsink
FEBS Journal | 1997
Oene R. Veltman; Gert Vriend; Florence Hardy; Johanna Mansfeld; Bertus van den Burg; Gerard Venema; Vincent G. H. Eijsink
FEBS Journal | 2001
Arno de Kreij; Bertus van den Burg; Oene R. Veltman; Gert Vriend; Gerard Venema; Vincent G. H. Eijsink
Protein Engineering | 1992
Vincent G. H. Eijsink; Gerrit Vriend; Bertus van den Burg; J.Rob van der Zee; Oene R. Veltman; Ben K. Stulp; Gerard Venema
Biotechnology and Applied Biochemistry | 1998
B. van den Burg; V.G.H. Eijsink; Gert Vriend; Oene R. Veltman; G Venema
Archive | 1998
Den Burg Lambertus Van; Oene R. Veltman; Gerard Venema
