P.G. Reddy

Effects of bovine respiratory disease viruses and isoprinosine on bovine leukocyte function in vitro

Peripheral blood mononuclear cells obtained from 4- to 6-month-old-calves were inoculated in vitro with bovine herpesvirus-1, parainfluenza-3, or bovine virus diarrhea viruses. No increase in infectious virus progeny was observed; however, the viruses were detected in the cells for at least 96 h post-infection without any significant reduction in cell viability. The three viruses, either alone or in combination, suppressed phytohemagglutinin-induced proliferation of the mononuclear cells. The greatest suppression was observed in cultures inoculated with bovine virus diarrhea virus. Addition of isoprinosine partially restored this viral-induced suppression of proliferative response, and the efficiency of reversal was greater in bovine virus diarrhea virus-infected cells. Interleukin-2 activity was higher in cultures of virus-infected mononuclear cells than in cultures of non-infected cells.

Effect of serum from Vitamin E-supplemented calves on Infectious Bovine Rhinotracheitis Virus replication

This report is brought to you for free and open access by New Prairie Press. It has been accepted for inclusion in Kansas Agricultural Experiment Station Research Reports by an authorized administrator of New Prairie Press. Copyright 1985 Kansas State University Agricultural Experiment Station and Cooperative Extension Service.

Interrelationship between hypersensitivity to soybean proteins and growth performance in early-weaned pigs.

The objective of this growth trial was to determine the interrelationship between immunological criteria, gut morphology, and performance of starter pigs fed soybean proteins processed by different methods. One hundred twenty-five pigs were orally infused with 6 g/d of either dried skim milk, soybean meal (48% CP), soy protein concentrate, extruded soy protein concentrate, or experimental soy protein concentrate from 7 to 11 d of age and then fed a diet containing the same protein sources from weaning (d 21) to 35 d of age. All pigs were fed a corn-soybean meal diet containing 10% dried whey, 1.25% lysine, and 3% soybean oil for the remaining 21 d of the experiment. Xylose absorption and anti-soy immunoglobulin G (IgG) titers were measured on d 6 postweaning, and skin-fold thickness after intradermal injection of protein extracts was measured on d 7 postweaning. A total of 25 pigs (five pigs/treatment) was euthanatized on d 7 postweaning. Villus height and crypt depth from duodenum samples were measured. These measurements were obtained to elucidate a relationship between the hypersensitivity responses to soybean products and growth performance of baby pigs. Pigs fed diets containing soybean meal had a lower (P less than .05) rate of gain (d 0 to 14) and villus height, higher (P less than .01) serum anti-soy IgG titers, and increased skin-fold thickness (d 6 and 7 postweaning) after intradermal injection compared with those fed dried skim milk. Pigs fed other soy proteins also had lower ADG from d 0 to 14 postweaning; however, pigs fed moist extruded soy protein concentrate tended (P less than .09) to have higher ADG and improved feed utilization when compared with pigs fed soybean meal (d 0 to 14).(ABSTRACT TRUNCATED AT 250 WORDS)

Soybean products as a protein source in milk replacers for calves

This report is brought to you for free and open access by New Prairie Press. It has been accepted for inclusion in Kansas Agricultural Experiment Station Research Reports by an authorized administrator of New Prairie Press. Copyright 1986 Kansas State University Agricultural Experiment Station and Cooperative Extension Service.

Effect of supplemental Vitamin E on the performance, metabolic profiles, and immune responses of dairy calves.

Forty-six Holstein heifer calves were used from birth to 3 rno to study the effect of supplemental vitamin E at 1400 or 2800 mg dl-a.-tocopherol acetate given orally at weekly intervals or 1400 mg dl-a-tocopherol by intramuscular injection. Weekly starter consumption was 10 to 27 % more (P=.12) and weekly weight gains were 9 to 25% more (P=.13) in supplemented calves. Creatine phosphokinase activity was negatively correlated with serurn tocopherol concentrations, indicating a subclinical muscular dystrophy in unsupplemented calves. Lymphocyte stimulation indices were positively correlated with serum tocopherol concentration. Calves given high level of oral supplementation had higher IgM antibody concentration. It was concluded that supplemental vitamin E is beneficial for calves reared on conventional complete starters to increase disease resistance and to obtain optimum performance.; Dairy Day, 1984, Kansas State University, Manhattan, KS, 1984;