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Vitamins and Hormones Series | 1962

Chemistry of Vitamin E

O. Isler; P. Schudel; Hans Mayer; J. Würsch; R. Rüegg

Publisher Summary Vitamin E occurs in vegetable oils and acts as a biological antioxidant. It is distributed throughout the tissues of animals and man, and its deficiency causes a variety of syndromes in the animal organism. This chapter shows the preferred routes to specific labelings of vitamin E and has indicated the chemical research that is necessary for getting a final stereochemical insight into the tocopherol molecules. Similar investigations on related natural chromanols and ohromenols might help to elucidate their mutual biogenetic relationship. Furthermore, the reported chemical interconversions of trimethylphytylbenzoquinone into either α-tocopherol or 3,4-dehydro-α-tocopherol may indicate some biological interrelations, which might also be common to the related natural quinones, chromanols, and chromenols listed in this chapter.


Helvetica Chimica Acta | 1963

Über die Chemie des Vitamins E. 3. Mitteilung. Die Totalsynthese von (2R, 4′R, 8′R)‐ und (2S, 4′R, 8′R)‐α‐Tocopherol

Hans Mayer; P. Schudel; R. Rüegg; O. Isler


Helvetica Chimica Acta | 1963

Über die Chemie des Vitamins E. 2. Mitteilung. Die Struktur des Kaliumferricyanid‐Oxydationsproduktes von α‐Tocopherol

P. Schudel; Hans Mayer; J. Metzger; R. Rüegg; O. Isler


Helvetica Chimica Acta | 1963

Über die Chemie des Vitamins E. 1. Mitteilung. Die Umkehrung der Konfiguration am Kohlenstoffatom 2 von natürlichem (2 R, 4′ R, 8′ R)-α-Tocopherol

P. Schudel; Hans Mayer; J. Metzger; R. Rüegg; O. Isler


Helvetica Chimica Acta | 1963

102. Die absolute Konfiguration des natürlichen ä-Tocopherols: 4. Mitteilung)

Hans Mayer; P. Schudel; R. Rüegg; O. Isler


Helvetica Chimica Acta | 1963

Über die Chemie des Vitamins E. 5. Mitteilung. Die Synthese von rac. all‐trans‐ζ1‐ und‐ϵ‐Tocopherol

P. Schudel; Hans Mayer; J. Metzger; R. Rüegg; O. Isler


Helvetica Chimica Acta | 1961

Synthesen in der Carotinoid‐Reihe. 18. Mitteilung. Synthese von 7′, 8′‐Dihydro‐γ‐carotin (β‐Zeacarotin) und 3′,4′‐Dehydro‐γ‐carotin (Torulin)

R. Rüegg; Ulrich Schwieter; Gottlieb Ryser; P. Schudel; O. Isler


Helvetica Chimica Acta | 1961

Synthesen in der Carotinoid‐Reihe. 17. Mittelung. γ‐Carotin sowie d,l‐α‐ und β‐Carotin aus Dehydro‐β‐apo‐12′‐carotinal(C25)

R. Rüegg; Ulrich Schwieter; Gottlieb Ryser; P. Schudel; O. Isler


Helvetica Chimica Acta | 1964

Über die Chemie des Vitamins E 6. Mitteilung Die Totalsynthese der beiden Enantiomeren des α-Tocopherol-Harnmetaboliten (SIMON- Metaboliten)†‡

Hans Mayer; P. Schudel; R. Rüegg; O. Isler


Archive | 1969

Production of chromanes

Hans Mayer; R. Rüegg; P. Schudel

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