Patrice C. Belanger | Researchain

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Journal of The Chemical Society-perkin Transactions 1 | 1986

Synthesis of 2,3,4,4a,9,9a-hexahydro-3,9-methano-1H-indeno[2,1-c]pyridine and some N-substituted derivatives

Patrice C. Belanger; Haydn W. R. Williams

The construction of the very rigid 2,3,4,4a,9,9a-hexahydro-3,9-methano-1H-indeno[2,1-c]pyridine system by three different routes is presented. One of the routes led also to another novel azabenzotricyclodecane system, viz. to the compound 2-(p-tolylsulphonyl)-1,2,3,3a,8,8a-hexahydro-3,8-ethanoindeno[1,2-c]pyrrole, which was the result of a skeletal rearrangement. The last of the routes gives easy access to the title compound and its derivatives.

Journal of Organic Chemistry | 1986

Reductive deoxygenation of aryl aldehydes and ketones and benzylic, allylic, and tertiary alcohols by zinc iodide-sodium cyanoborohydride

C. K. Lau; Claude Dufresne; Patrice C. Belanger; Sylvie Pietre; John Scheigetz

Journal of Organic Chemistry | 1983

Synthesis, chemistry, and photochemical substitutions of 6,11-dihydro-5H-pyrrolo[2,1-b][3]benzazepin-11-ones

Yves Girard; Joseph G. Atkinson; Patrice C. Belanger; José J. Fuentes; Joshua Rokach; C. Stanley Rooney; David C. Remy; Cecilia A. Hunt

Canadian Journal of Chemistry | 1986

Preparation of exo-6-benzyl-exo-2-(m-hydroxyphenyl)-1-dimethylaminomethylbicyclo[2.2.2]octane. A non-peptide mimic of enkephalins

Patrice C. Belanger; Claude Dufresne

Archive | 1983

Leukotriene antagonists, their production, and compositions containing them

Patrice C. Belanger; Rejean Fortin; Yvan Guindon; Joshua Rokach; Christiane Yoakim

Archive | 1985

BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES, THEIR USE IN INHIBITING MAMMALIAN LEUKOTRIENE BIOSYNTHESIS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES

Patrice C. Belanger; John Scheigetz; Joshua Rokach

Journal of Medicinal Chemistry | 1992

Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase.

Cheuk-Kun Lau; Patrice C. Belanger; Claude Dufresne; John Scheigetz; Michel Therien; Fitzsimmons B; Robert N. Young; Ford-Hutchinson Aw; Denis Riendeau; Danielle Denis

Advances in prostaglandin, thromboxane, and leukotriene research | 1987

L-651,392: a novel, potent and selective 5-lipoxygenase inhibitor.

Yvan Guindon; Yves Girard; Maycock Al; A. W. Ford-Hutchinson; Joseph G. Atkinson; Patrice C. Belanger; Aimee Dallob; DeSousa D; Dougherty H; Egan R

Canadian Journal of Physiology and Pharmacology | 1987

L-656,224 (7-chloro-2-[(4-methoxyphenyl)methyl]-3-methyl-5-propyl-4-benzofuranol): a novel, selective, orally active 5-lipoxygenase inhibitor

Patrice C. Belanger; Maycock Al; Yvan Guindon; T. Bach; A. L. Dollob; C. Dufresne; A. W. Ford-Hutchinson; P. H. Gale; S. Hopple; Cheuk-Kun Lau; L. G. Letts; S. Luell; C. S. McFarlane; E. MacIntyre; R. Meurer; D. K. Miller; H. Piechuta; D. Riendeau; Joshua Rokach; C. Rouzer; J. Scheigetz

Canadian Journal of Chemistry | 1982