Patrícia de Freitas

Human herpesvirus 8 (HHV-8) detected by nested polymerase chain reaction (PCR) in HIV patients with or without Kaposi's sarcoma. An analytic cross-sectional study

CONTEXT AND OBJECTIVE Kaposis sarcoma (KS) is a common neoplastic disease in AIDS patients. The aim of this study was to evaluate the frequency of human herpesvirus 8 (HHV-8) infection in human immunodeficiency virus (HIV)-infected patients, with or without KS manifestations and correlate HHV-8 detection with KS staging. DESIGN AND SETTING Analytic cross-sectional study conducted in a public tertiary-level university hospital in Ribeirão Preto, São Paulo, Brazil. METHODS Antibodies against HHV-8 lytic-phase antigens were detected by means of the immunofluorescence assay. HHV-8 DNA was detected in the patient samples through a nested polymerase chain reaction (nested PCR) that amplified a region of open reading frame (ORF)-26 of HHV-8. RESULTS Anti-HHV-8 antibodies were detected in 30% of non-KS patients and 100% of patients with KS. Furthermore, the HHV-8 DNA detection rates observed in HIV-positive patients with KS were 42.8% in serum, 95.4% in blood samples and 100% in skin biopsies; and in patients without KS, the detection rate was 4% in serum. Out of the 16 serum samples from patients with KS-AIDS who were classified as stage II, two were positive (12.5%); and out of the 33 samples from patients in stage IV, 19 (57.6%) were positive. CONCLUSION We observed an association between HHV-8 detection and disease staging, which was higher in the serum of patients in stage IV. This suggests that detection of HHV-8 DNA in serum could be very useful for clinical assessment of patients with KS and for monitoring disease progression.

Changes in physiological and behavioral parameters of preterm infants undergoing body hygiene: a systematic review

Objetivo Verificar o efeito do banho na temperatura corporal de recem-nascidos pre-termo (RNPT). Metodo Revisao sistematica realizada nas fontes eletronicas bibliograficas BVS/Lilacs, Cumulative Index of Nursing and Allied Health (CINAHL), Cochrane Library, Google Scholar, PubMed, SCOPUS e Web of Science, utilizando a combinacao de descritores, palavras-chave e termos livres. A pergunta da revisao foi ajustada ao acronimo PICO (Paciente/populacao, Intervencao, Intervencao controle/comparativa, Desfecho analisado). As publicacoes selecionadas foram avaliadas de acordo com os niveis de evidencia e graus de recomendacao para estudos de eficacia/efetividade estabelecidos pelo Instituto Joanna Briggs. Resultados Foram identificadas 824 publicacoes e quatro estudos atenderam aos criterios de inclusao, dos quais tres analisaram o efeito do banho de esponja e um o efeito do banho de imersao. Conclusao O banho de esponja mostrou queda da temperatura corporal estatisticamente significante, enquanto no banho de imersao a temperatura corporal permaneceu estavel, embora tenham sido estudados RNPT tardios.Objective To verify the effect of bathing on the body temperature of preterm infants (PTI). Method Systematic review conducted in the following bibliographic electronic sources: Biblioteca Virtual em Saúde/Lilacs (BVS), Cumulated Index of Nursing and Allied Health Literature (CINAHL), Cochrane Library, Google Scholar, PubMed, SCOPUS and Web of Science, using a combination of search terms, keywords and free terms. The review question was adjusted to the PICO acronym (Patient/population, Intervention, Control/comparative intervention, Outcome). The selected publications were evaluated according to levels of evidence and grades of recommendation for efficacy/effectiveness studies, as established by the Joanna Briggs Institute. Results Eight hundred and twenty four (824) publications were identified and four studies met the inclusion criteria, of which three analyzed the effect of sponge baths and the effect of immersion baths. Conclusion Sponge baths showed a statistically significant drop in body temperature, while in immersion baths the body temperature remained stable, although they studied late preterm infants.

Profile of mothers of newborns with blood glucose control in the first hours of life

Alguns fatores maternos associados ao quadro de hipoglicemia neonatal indicam a monitoracao dos niveis glicemicos nas primeiras 24 horas de vida. O estudo objetivou descrever as caracteristicas socio-demograficas e obstetricas de maes de neonatos com controle de glicemia capilar nas primeiras 24 horas de vida, internadas em Alojamento Conjunto de um Hospital Amigo da Crianca. Estudo descritivo-exploratorio que analisou dados de 380 prontuarios medicos de maes internadas entre julho e dezembro de 2006, na unidade de Alojamento Conjunto do Hospital Universitario da Universidade de Sao Paulo. Diabetes gestacional foi verificado em 18 (5,6%) maes; nenhuma tratou com hipoglicemiante oral; 53 (16,2%) tiveram hipertensao arterial na gestacao, e 17 (32,1%) fizeram uso de anti-hipertensivo; 215 (56,6%) receberam soro glicosado, 5% no trabalho de parto e parto. Estudos correlacionais analisando variaveis maternas e ocorrencia de hipoglicemia neonatal devem ser realizados, objetivando identificar os fatores preditores desta morbidade neonatal.Some maternal factors associated with neonatal hypoglycemia justify monitoring blood glucose levels in the first 24 hours of life. The objective of this study was to describe the socio-demographic and obstetric characteristics of mothers to newborns undergoing capillary blood glucose control in the first 24 hours of life, hospitalized in a rooming-in maternity ward of a Baby Friendly Hospital. This is a descriptive exploratory study which involved the analysis of data from 380 medical records of mothers hospitalized from July to December, 2006 at the maternity ward of the University of São Paulo Teaching Hospital. It was found that 18 (5.6%) mothers developed gestational diabetes, none of them were treated with oral hypoglycemic agents, 53 (16.2%) had hypertension during pregnancy and 17 (32.1%) used anti-hypertensive medication, 215 (56.6%) received glucose 5% continuous infusion during labor and delivery. Correlation studies linking maternal variables and neonatal hypoglycemia are needed to identify the predicting factors of this neonatal morbidity.

Perfil das mães de neonatos com controle glicêmico nas primeiras horas de vida

Alguns fatores maternos associados ao quadro de hipoglicemia neonatal indicam a monitoracao dos niveis glicemicos nas primeiras 24 horas de vida. O estudo objetivou descrever as caracteristicas socio-demograficas e obstetricas de maes de neonatos com controle de glicemia capilar nas primeiras 24 horas de vida, internadas em Alojamento Conjunto de um Hospital Amigo da Crianca. Estudo descritivo-exploratorio que analisou dados de 380 prontuarios medicos de maes internadas entre julho e dezembro de 2006, na unidade de Alojamento Conjunto do Hospital Universitario da Universidade de Sao Paulo. Diabetes gestacional foi verificado em 18 (5,6%) maes; nenhuma tratou com hipoglicemiante oral; 53 (16,2%) tiveram hipertensao arterial na gestacao, e 17 (32,1%) fizeram uso de anti-hipertensivo; 215 (56,6%) receberam soro glicosado, 5% no trabalho de parto e parto. Estudos correlacionais analisando variaveis maternas e ocorrencia de hipoglicemia neonatal devem ser realizados, objetivando identificar os fatores preditores desta morbidade neonatal.Some maternal factors associated with neonatal hypoglycemia justify monitoring blood glucose levels in the first 24 hours of life. The objective of this study was to describe the socio-demographic and obstetric characteristics of mothers to newborns undergoing capillary blood glucose control in the first 24 hours of life, hospitalized in a rooming-in maternity ward of a Baby Friendly Hospital. This is a descriptive exploratory study which involved the analysis of data from 380 medical records of mothers hospitalized from July to December, 2006 at the maternity ward of the University of São Paulo Teaching Hospital. It was found that 18 (5.6%) mothers developed gestational diabetes, none of them were treated with oral hypoglycemic agents, 53 (16.2%) had hypertension during pregnancy and 17 (32.1%) used anti-hypertensive medication, 215 (56.6%) received glucose 5% continuous infusion during labor and delivery. Correlation studies linking maternal variables and neonatal hypoglycemia are needed to identify the predicting factors of this neonatal morbidity.

A saúde neonatal na perspectiva de atenção contínua à saúde da mulher e da criança

The study is a literature review of theses and dissertations concluded from 2000 to 2009 developed by the Obstetric and Neonatal Nursing Research Group and Breastfeeding Center for Studies and Research of Nursing School, University of São Paulo, which focused on the maternal and perinatal impact on neonatal health. The scientific production shows agreement with the guidelines to promote neonatal and infant health established by national and international health agencies.The study is a literature review of theses and dissertations concluded from 2000 to 2009 developed by the Obstetric and Neonatal Nursing Research Group and Breastfeeding Center for Studies and Research of Nursing School, University of Sao Paulo, which focused on the maternal and perinatal impact on neonatal health. The scientific production shows agreement with the guidelines to promote neonatal and infant health established by national and international health agencies.

Las variaciones de los parámetros fisiológicos y de comportamiento de los recién nacidos pretérminos sometidos a baño de inmersión: una revisión sistemática

Objetivo Verificar o efeito do banho na temperatura corporal de recem-nascidos pre-termo (RNPT). Metodo Revisao sistematica realizada nas fontes eletronicas bibliograficas BVS/Lilacs, Cumulative Index of Nursing and Allied Health (CINAHL), Cochrane Library, Google Scholar, PubMed, SCOPUS e Web of Science, utilizando a combinacao de descritores, palavras-chave e termos livres. A pergunta da revisao foi ajustada ao acronimo PICO (Paciente/populacao, Intervencao, Intervencao controle/comparativa, Desfecho analisado). As publicacoes selecionadas foram avaliadas de acordo com os niveis de evidencia e graus de recomendacao para estudos de eficacia/efetividade estabelecidos pelo Instituto Joanna Briggs. Resultados Foram identificadas 824 publicacoes e quatro estudos atenderam aos criterios de inclusao, dos quais tres analisaram o efeito do banho de esponja e um o efeito do banho de imersao. Conclusao O banho de esponja mostrou queda da temperatura corporal estatisticamente significante, enquanto no banho de imersao a temperatura corporal permaneceu estavel, embora tenham sido estudados RNPT tardios.Objective To verify the effect of bathing on the body temperature of preterm infants (PTI). Method Systematic review conducted in the following bibliographic electronic sources: Biblioteca Virtual em Saúde/Lilacs (BVS), Cumulated Index of Nursing and Allied Health Literature (CINAHL), Cochrane Library, Google Scholar, PubMed, SCOPUS and Web of Science, using a combination of search terms, keywords and free terms. The review question was adjusted to the PICO acronym (Patient/population, Intervention, Control/comparative intervention, Outcome). The selected publications were evaluated according to levels of evidence and grades of recommendation for efficacy/effectiveness studies, as established by the Joanna Briggs Institute. Results Eight hundred and twenty four (824) publications were identified and four studies met the inclusion criteria, of which three analyzed the effect of sponge baths and the effect of immersion baths. Conclusion Sponge baths showed a statistically significant drop in body temperature, while in immersion baths the body temperature remained stable, although they studied late preterm infants.

Variações nos parâmetros fisiológicos e comportamentais de recém-nascidos pré-termo submetidos à higienização corporal: revisão sistemática

Objetivo Verificar o efeito do banho na temperatura corporal de recem-nascidos pre-termo (RNPT). Metodo Revisao sistematica realizada nas fontes eletronicas bibliograficas BVS/Lilacs, Cumulative Index of Nursing and Allied Health (CINAHL), Cochrane Library, Google Scholar, PubMed, SCOPUS e Web of Science, utilizando a combinacao de descritores, palavras-chave e termos livres. A pergunta da revisao foi ajustada ao acronimo PICO (Paciente/populacao, Intervencao, Intervencao controle/comparativa, Desfecho analisado). As publicacoes selecionadas foram avaliadas de acordo com os niveis de evidencia e graus de recomendacao para estudos de eficacia/efetividade estabelecidos pelo Instituto Joanna Briggs. Resultados Foram identificadas 824 publicacoes e quatro estudos atenderam aos criterios de inclusao, dos quais tres analisaram o efeito do banho de esponja e um o efeito do banho de imersao. Conclusao O banho de esponja mostrou queda da temperatura corporal estatisticamente significante, enquanto no banho de imersao a temperatura corporal permaneceu estavel, embora tenham sido estudados RNPT tardios.Objective To verify the effect of bathing on the body temperature of preterm infants (PTI). Method Systematic review conducted in the following bibliographic electronic sources: Biblioteca Virtual em Saúde/Lilacs (BVS), Cumulated Index of Nursing and Allied Health Literature (CINAHL), Cochrane Library, Google Scholar, PubMed, SCOPUS and Web of Science, using a combination of search terms, keywords and free terms. The review question was adjusted to the PICO acronym (Patient/population, Intervention, Control/comparative intervention, Outcome). The selected publications were evaluated according to levels of evidence and grades of recommendation for efficacy/effectiveness studies, as established by the Joanna Briggs Institute. Results Eight hundred and twenty four (824) publications were identified and four studies met the inclusion criteria, of which three analyzed the effect of sponge baths and the effect of immersion baths. Conclusion Sponge baths showed a statistically significant drop in body temperature, while in immersion baths the body temperature remained stable, although they studied late preterm infants.

Knowledge about HIV/AIDS on women’s health: a descriptive study with undergraduates

Aim: to verify the information and knowledge about HIV/AIDS on womens health of students enrolled in the nursing undergraduate course at a public university of Sao Paulo state, Brazil. Method: This is a descriptive study, initially assessing 56 nursing students studying Women’s Health during the academic year of 1998/99. A further 51 students were assessed during 2010. The data was collected via a questionnaire, filled in by the students before a class regarding HIV/AIDS and women. This project was approved by the Ethics in Research Committee and by the Research Commission of the institution. Results: A decrease in the degree of the student’s knowledge was observed in 2010 in comparison to 1998/9. On the other hand, the 2010 respondents answered more questions regarding vertical transmission of the virus/disease correctly. Conclusions: This study suggests that changing teaching strategies to include activities in the field, allowing early contact between students and clientele may be beneficial.

Perfil de las madres de neonatos con control glucémico en las primeras horas de vida

Alguns fatores maternos associados ao quadro de hipoglicemia neonatal indicam a monitoracao dos niveis glicemicos nas primeiras 24 horas de vida. O estudo objetivou descrever as caracteristicas socio-demograficas e obstetricas de maes de neonatos com controle de glicemia capilar nas primeiras 24 horas de vida, internadas em Alojamento Conjunto de um Hospital Amigo da Crianca. Estudo descritivo-exploratorio que analisou dados de 380 prontuarios medicos de maes internadas entre julho e dezembro de 2006, na unidade de Alojamento Conjunto do Hospital Universitario da Universidade de Sao Paulo. Diabetes gestacional foi verificado em 18 (5,6%) maes; nenhuma tratou com hipoglicemiante oral; 53 (16,2%) tiveram hipertensao arterial na gestacao, e 17 (32,1%) fizeram uso de anti-hipertensivo; 215 (56,6%) receberam soro glicosado, 5% no trabalho de parto e parto. Estudos correlacionais analisando variaveis maternas e ocorrencia de hipoglicemia neonatal devem ser realizados, objetivando identificar os fatores preditores desta morbidade neonatal.Some maternal factors associated with neonatal hypoglycemia justify monitoring blood glucose levels in the first 24 hours of life. The objective of this study was to describe the socio-demographic and obstetric characteristics of mothers to newborns undergoing capillary blood glucose control in the first 24 hours of life, hospitalized in a rooming-in maternity ward of a Baby Friendly Hospital. This is a descriptive exploratory study which involved the analysis of data from 380 medical records of mothers hospitalized from July to December, 2006 at the maternity ward of the University of São Paulo Teaching Hospital. It was found that 18 (5.6%) mothers developed gestational diabetes, none of them were treated with oral hypoglycemic agents, 53 (16.2%) had hypertension during pregnancy and 17 (32.1%) used anti-hypertensive medication, 215 (56.6%) received glucose 5% continuous infusion during labor and delivery. Correlation studies linking maternal variables and neonatal hypoglycemia are needed to identify the predicting factors of this neonatal morbidity.

La atención neonatal en la perspectiva de la atención continua a la salud de las mujeres y niños

The study is a literature review of theses and dissertations concluded from 2000 to 2009 developed by the Obstetric and Neonatal Nursing Research Group and Breastfeeding Center for Studies and Research of Nursing School, University of São Paulo, which focused on the maternal and perinatal impact on neonatal health. The scientific production shows agreement with the guidelines to promote neonatal and infant health established by national and international health agencies.The study is a literature review of theses and dissertations concluded from 2000 to 2009 developed by the Obstetric and Neonatal Nursing Research Group and Breastfeeding Center for Studies and Research of Nursing School, University of Sao Paulo, which focused on the maternal and perinatal impact on neonatal health. The scientific production shows agreement with the guidelines to promote neonatal and infant health established by national and international health agencies.